Mukherjee Cardiovascular Innovations Lab

The Mukherjee Cardiovascular Innovations Lab harnesses multimodality imaging techniques to refine risk prediction of adverse clinical outcomes in autoimmune and rheumatologic diseases.

ResearchCardiovascular Imaging

Multimodality imaging techniques can enhance diagnostic precision for disease screening and monitoring of cardiopulmonary involvement in systemic inflammatory, autoimmune, and rheumatologic diseases.

The Mukherjee Cardiovascular Innovations Lab harnesses cutting-edge imaging techniques to explore cardiovascular manifestations and enhance the screening, early detection, and prediction of adverse clinical events across a broad range of autoimmune diseases.

Principal InvestigatorDr. Monica Mukherjee, M.D., M.P.H., FAHA, FACC, FASE

Monica Mukherjee, M.D., M.P.H., is an associate professor of medicine in the Johns Hopkins University Division of Cardiology. She is also associate director of the Johns Hopkins echocardiography program and medical director at the echocardiography laboratory at Johns Hopkins Bayview Medical Center. She has extensive clinical and research expertise in multimodality cardiovascular imaging and advanced echocardiography.

Dr. Mukherjee graduated summa cum laude with dual degrees in behavioral neuroscience and psychology from the University of Florida. She received her doctorate of medicine from the George Washington University (GW), and completed internal medicine training at Drexel University and a fellowship in cardiovascular disease at GW. Dr. Mukherjee is also a graduate of the Johns Hopkins Bloomberg School of Public Health and received her M.P.H. focusing on epidemiological and biostatistical methods.

Dr. Mukherjee is funded by the National Scleroderma Foundation, the National Institutes of Health/National Heart, Lung and Blood Institute, and the Department of Defense.

Meet Dr. Mukherjee

Research Team

Garrett Goldin, B.S./M.S.

Senior Research Program Coordinator, Echocardiography

Garrett Goldin graduated with honors from The Johns Hopkins University, earning both a Bachelor and Master of Science degree in neuroscience. During his university education, Garrett conducted research at the Dynamic Perception Lab under the mentorship of Dr. Jason Fischer, mainly investigating the link between neural circuits underlying intuitive physical processing and action planning in the human brain. Now working on several echocardiographic projects, Garrett aims to leverage his passions for both research and clinical medicine to one day become a physician himself. Outside of his academic interests, Garrett likes to ski, surf, hike, and play electric guitar, bass, and drums.

Ryan Osgueritchian, M.D.

Postdoctoral Fellow

Ryan Osgueritchian is a postdoctoral fellow with a keen interest in pursuing a career as a physician-researcher in cardiology. He graduated from the American University of Beirut Faculty of Medicine in June 2023, where he developed a foundation in medical knowledge and clinical skills. His academic and research interests focus on advancing our understanding of cardiovascular diseases, mainly through research and clinical applications. He also enjoys playing soccer and hiking in his leisure time, which helps him to maintain a balanced and active lifestyle.

Hoda Mombeini, M.D.

Postdoctoral Fellow

Hoda Mombeini is a postdoctoral research fellow with a robust background in both clinical practice and research in cardiology. Following medical school, she specialized in cardiovascular disease and completed an echocardiography fellowship at Rajaie Heart Center in Iran. Hoda has held positions as an attending cardiologist at Ahvaz University and Tehran University of Medical Sciences in Iran, where she has actively led and contributed to numerous cardiology research projects. Her primary research interest is the role of advanced echocardiography in the early management of cardiovascular diseases, with a particular focus on left and right ventricular dysfunction and valvular heart disease. Outside of her professional life, she enjoys gym workouts, hiking, baking and singing.

Abhi Gami, M.D.

Medical Resident

Abhi Gami is a PGY-3 internal medicine resident in the Osler Internal Medicine Residency. He is interested in preventive cardiology, cardiovascular epidemiology and advanced echocardiography. His research in the Mukherjee Lab has focused on investigation of right ventricle to pulmonary artery coupling assessed using echocardiography and cardiac MRI. He is interested in investigation of right ventricle function in well-characterized cardiac imaging and cardiovascular cohort studies. In his free time, he enjoys walking along the harbor in Baltimore, reading, photography and travel.

Katherine Lang, M.D.

Medical Resident

Kate grew up in Denver prior to moving to Ohio to attend Kenyon College, where she studied biology and played varsity lacrosse. After graduating, she became a Certified Nurse Assistant, attended nursing school and worked as an RN in a procedural cardiology unit. She was inspired by the many wonderful physicians she worked with and decided to attend Case Western Reserve University for medical school. In the Mukherjee lab, Kate’s research focuses on the impact of mitral and aortic valve disease on left atrial remodeling. Outside of medicine, she enjoys running, fly fishing, being outdoors and exploring the food scene and running routes in Baltimore.

Vivek Jani, B.S./M.S.

Medical Student

Vivek Jani is an M.D./Ph.D. candidate at the Johns Hopkins University School of Medicine, where he is primarily advised by Dr. David Kass. He has extensive expertise in translational research, harnessing advanced imaging techniques and machine learning methods in patients with heart failure with preserved ejection fraction (HFpEF). Vivek completed his B.S./M.S. in biomedical engineering at the University of California, San Diego, working in the Functional Cardiovascular Engineering Lab under Dr. Pedro Cabrales. In 2022, Vivek received the prestigious Melvin L. Marcus Early Career Investigator Award in Basic Cardiovascular Sciences from the American Heart Association. He is also the recipient of the NIH/NHLBI F30 grant and the AHA Pre-Doctoral Fellowship. At the Mukherjee Research Lab, Vivek’s research focuses on multiparametric clinical phenotyping of systemic sclerosis patients with HFpEF, a project that earned him the National Scleroderma Foundation Dr. Arnold Postlethwaite Pre-Doctoral Summer Fellowship in 2022. Outside of his academic pursuits, Vivek enjoys exercising, traveling and hiking.

Ethan Knight, B.S.

Medical Student

Ethan Knight is a fourth-year medical student at the Johns Hopkins School of Medicine. He previously graduated from the University of Washington in Seattle, where he worked in the Dichek Lab developing gene therapy strategies for atherosclerosis. His current work in the Mukherjee Lab focuses on pulmonary artery distensibility and predictive modeling for HFpEF in patients with scleroderma. Outside of school and research, he enjoys playing soccer (and rooting for the Seattle Sounders), tending to his garden, and discovering new places to eat in Baltimore.

Lab Alumni

Jim Lu, M.D.

Was: Medical Student at Johns Hopkins University
Now: Medical Resident at Brigham and Women’s Hospital, Harvard University

Brigitte Kazzi, M.D.

Was: Medical Resident at Johns Hopkins University
Now: Clinical Fellow at Brigham and Women’s Hospital, Harvard University

Selected Publications

Unique Abnormalities in Right Ventricular Longitudinal Strain in Systemic Sclerosis Patients
Mukherjee M, Chung SE, Ton VK, Hummers LK, Wigley FM, Abraham TP, Shah AA. Unique Abnormalities in Right Ventricular Longitudinal Strain in Systemic Sclerosis Patients. Circ Cardiovasc Imaging. 2016;Jun;9(6):e003792. PMID: 27266598 PMCID: PMC4902176

Defining minimal detectable difference in echocardiographic measures of right ventricular function in systemic sclerosis
Mukherjee M, Mercurio V, Balasubramanian A, Shah AA, Hsu S, Simpson CE, Damico R, Kolb TM, Hassoun PM, Mathai SC. Reliability, Repeatability, and Reproducibility of Echocardiographic Measures of Right Ventricular Function in Systemic Sclerosis. Arthritis Res Ther. 2022 Jun 18;24(1):146. doi: 10.1186/s13075-022-02835-5. PMID: 35717399

Normative Values of Echocardiographic Chamber Size and Function in Older Healthy Adults: The Multi-Ethnic Study of Atherosclerosis
Mukherjee M, Strom JB, Afilalo J, Hu M, Beussink-Nelson L, Kim J, Addetia K, Bertoni AG, Gottdiener JS, Michos ED, Gardin JM, Shah SJ, Freed BH. Normative Values of Echocardiographic Chamber Size and Function in Older Healthy Adults: The Multi-Ethnic Study of Atherosclerosis. Circ

Novel Imaging Approaches to Cardiac Manifestations of Systemic Inflammatory Diseases: JACC Scientific Statement
Weber BN, Paik JJ, Aghayev A, Klein AL, Mavrogeni SI, Yu PB, Mukherjee M. Novel Imaging Approaches to Cardiac Manifestations of Systemic Inflammatory Diseases: JACC Scientific Statement. J Am Coll Cardiol. 2023 Nov 28;82(22):2128-2151. doi: 10.1016/j.jacc.2023.09.819. PMID: 37993205; PMCID: PMC11238243.

Right ventricular longitudinal strain is diminished in systemic sclerosis compared with idiopathic pulmonary arterial hypertension
Mukherjee M, Mercurio V, Tedford RJ, Shah AA, Hsu S, Mullin CJ, Sato T, Damico R, Kolb TM, Mathai SC, Hassoun PM. Right Ventricular Longitudinal Strain is Diminished in Systemic Sclerosis Compared to Idiopathic Pulmonary Arterial Hypertension. Eur Respir J. 2017;Nov 22;50(5):1701436. PMID: 29167303. PMID: 27266598 PMCID: PMC5843490

Assessment of right ventricular reserve utilizing exercise provocation in systemic sclerosis
Mukherjee M, Mercurio V, Hsu S, Mayer SA, Mathai SC, Hummers LK, Kass DA, Hassoun PM, Wigley FM, Shah AA. Assessment of right ventricular reserve using exercise provocation in systemic sclerosis. Int J Cardiovasc Imaging. 2021 April 16. doi: 10.1007/s10554-021-02237-9. PMID: 33860914

Optimal Method for Assessing Right Ventricular to Pulmonary Arterial Coupling in Older Healthy Adults: The Multi-Ethnic Study of Atherosclerosis
Jani VP, Strom JB, Gami A, Beussink-Nelson L, Patel R, Michos ED, Shah SJ, Freed BH, Mukherjee M. Optimal Method for Assessing Right Ventricular to Pulmonary Arterial Coupling in Older Healthy Adults: The Multi-Ethnic Study of Atherosclerosis. Am J Cardiol. 2024 Jul 1;222:11-19. doi: 10.1016/j.amjcard.2024.03.043. Epub 2024 Apr 19. PMID: 38643925; PMCID: PMC11175998.

Characteristics of Right Ventricular to Pulmonary Arterial Coupling and Association With Functional Status Among Older Aged Adults from the Multi-Ethnic Study of Atherosclerosis
Mukherjee M*, Ogunmoroti O, Kapoor K, Beussink-Nelson L, Min K, Freed BH, Hays AG, Shah SJ, Michos ED. Characteristics of Right Ventricular to Pulmonary Arterial Coupling and Association with Functional Status Among Older Aged Adults in the Multi-Ethnic Study of Atherosclerosis. Am J Cardiol. 2023 Apr 15;196:41-51. doi: 10.1016/j.amjcard.2023.03.016. PMID:

Full list of publications on PubMed

Contact Information

General Lab: 301 Mason Lord Drive, Suite 2438 | Baltimore, MD 21224
Email: [email protected]

Dr. Mukherjee: 301 Mason Lord Drive, Suite 2400 | Baltimore, MD 21224
Phone: 410-550-1120 | Fax: 410-550-1183
Email: [email protected]

Research Funding

The Mukherjee Cardiovascular Innovations Lab receives funding from the NIH/NHLBI, the Department of Defense and the National Scleroderma Foundation.

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Cardiovascular Research