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Paulus Lab

Publications

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  1. Sauvage F, Nguyen VP, Li Y, Harizaj A, Sebag J, Van Havere V, Fraire JC, Remaut K, Paulus YM, Braeckmans K, De Smedt SC. Laser-induced nanobubbles safely ablate vitreous opacities in vivo. Nature Nanotechnology 2022 May;17(5):552-559. https://doi.org/10.1038/s41565-022-01086-4.

  2. Park W, Nguyen VP, Jeon Y, Kim B, Li Y, Yi J, Kim H, Leem JW, Kim YL, Kim DR, Paulus YM, Lee CH. Biodegradable silicon nanoneedles for ocular drug delivery. Science Advances 2022, 8(13):eabn1772. http://dx.doi.org/10.1126/sciadv.abn1772

  3. Xu G, Khan N, Almazroa A, Pawar M, Besirli C, Paulus YM, Wang X, Demirci H. Safety Evaluation of Photoacoustic Tomography System for Intraocular Tumors. Trans Vis Sci Technol 2022;11(3):30. https://doi.org/10.1167/tvst.11.3.30

  4. Karthikesh MS, Wu S, Singh R, Paulus YM, Wang X, Yang X. Effect of Photo-Mediated Ultrasound Therapy on Nitric Oxide and Prostacyclin from endothelial cells. Applied Sciences 2022;12, 2617. https://doi.org/10.3390/app12052617

  5. Nguyen VP, Zhu T, Henry J, Zhang W, Wang X, Paulus YM. Multimodal in vivo Imaging of Retinal and Choroidal Vascular Occlusion. Photonics 2022, 9(3), 201. https://doi.org/10.3390/photonics9030201

  6. Qin Y, Yu Y, Fu J, Wang M, Yang X, Wang X, Paulus YM. Photo-mediated ultrasound therapy for the treatment of retinal neovascularization in rabbit eyes. Lasers in Surgery & Medicine 2022; 54: 747–757. https://doi.org/10.1002/lsm.23539

  7. Zeng Y, Nguyen VP, Li Y, Kang DH, Paulus YM, Kim J. Chorioretinal Hypoxia Detection Using Lipid-Polymer Hybrid Organic Room-Temperature Phosphorescent Nanoparticles. ACS Appl. Mater. Interfaces 2022 14(16):18182-93. http://doi.org/10.1021/acsami.2c02767

  8. Li X, Zhang X, Li Y, Wu X, Wang M, Tan X, Paulus YM, Fan X, Xueding Wang X. In vivo tracking of individual stem cells labeled with nanowire lasers using multimodality imaging. Biomedical Optics Express 1 Sep 2022;13 (9): 4706-4717. https://doi.org/10.1364/BOE.454558

  9. Jairath NK, Paulus YM, Yim A, Zhou Y, Parekh BJ, Jairath R, Musch DC, Rosenthal JM. Intra- and post-operative risk of retinal breaks during vitrectomy for macular hole and vitreomacular traction. PLOS ONE 2022;17(8):e0272333. http://doi.org/10.1371/journal.pone.0272333

  10. Bogaert B, Sauvage F, Guagliardo R, Muntean C, Nguyen VP, Pottie E, Wels M, Minnaert A-K, De Rycke R, Yang Q, Peer D, Sanders N, Remaut K, Paulus YM, Stove C, De Smedt SC, Raemdonck K. A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs. Journal of Controlled Release 2022 Aug 10; S0168-3659(22)00514-4. doi: 10.1016/j.jconrel.2022.08.009.

  11. Nguyen VP, Henry J, Zhe J, Kieu Q, Qian W, Fu Y, Wang X, Paulus YM. Age Differential Response to Bevacizumab Therapy in Choroidal Neovascularization in Rabbits. Experimental Eye Research. 13 August 2022 [Epub ahead of print]:109215. https://doi.org/10.1016/j.exer.2022.109215

  12. Qiu A, Yu Y, Huang J, Liu Q, Paulus YM, Fan W. A PRPH2 Gene Variant Detected in Retinitis Punctata Albescens with Congenital Hypertrophy of the Retinal Pigment Epithelium. European Journal of Ophthalmology 2022, 32(1), NP 134–138. https://doi.org/10.1177/1120672120962027

  13. Wu AM, Zhao PY, Wubben TJ, Hyde RA, Paulus YM, Johnson MW. Serology negative Bartonella neuroretinitis in an immunocompromised patient. Retinal Cases & Brief Reports 2022 Jan 1;16(1):36-39. doi: 10.1097/ICB.0000000000000995.

  14. Nguyen VP, Li Y, Henry J, Zhang W, Aaberg M, Jones S, Qian T, Wang X, Paulus YM. Plasmonic gold nanostar-enhanced multimodal photoacoustic microscopy and optical coherence tomography molecular imaging to evaluate choroidal neovascularization. ACS Sensors 2020 Oct 23; 5(10):3070-81. https://dx.doi.org/10.1021/acssensors.0c00908

  15. Nguyen VP, Qian W, Li Y, Liu B, Aaberg M, Henry J, Zhang W, Wang X, Paulus YM. Chain-like Gold Nanoparticle Clusters for Multimodal Photoacoustic Microscopy and Optical Coherence Tomography Enhanced Molecular Imaging. Nature Communications 2021 Jan 4;12(1):34. https://dx.doi.org/10.1038/s41467-020-20276-z

  16. Yu Y, Jayasundera KT, Servoss J, Olson DC, George C, Branham K, Ghodasra D, Lee P, Paulus YM. A Novel Think Tank Program to Promote Innovation and Strategic Planning in Ophthalmic Surgery. Perioperative Care and Operating Room Management 2021; 22:100147. https://doi.org/10.1016/j.pcorm.2020.100147

  17. Qin Y, Yu Y, Fu J, Xie X, Wang T, Woodward MA, Paulus YM, Yang X, Wang X. Photo-mediated ultrasound therapy for the treatment of corneal neovascularization in rabbit eyes. Trans Vis Sci Technol 2020 Dec 9;9(13):16. doi: 10.1167/tvst.9.13.16

  18. Li Y, Zhang W, Nguyen VP, Khan NW, Xia X, Wang X, Paulus YM. Retinal safety evaluation of photoacoustic microscopy. Experimental Eye Research 2021 Jan; 202:108368. doi: 10.1016/j.exer.2020.108368. PMID: 33242491

  19. Nguyen VP, Folz J, Li Y, Henry J, Zhang W, Qian T, Wang X, Paulus YM. Indocyanine green-enhanced multimodal photoacoustic microscopy and optical coherence tomography molecular imaging of choroidal neovascularization. J Biophotonics 2021;14(5):e202000458. doi: 10.1002/jbio.202000458.

  20. Yu Y, Qin Y, Fu J, Li Y, Zhang W, Zhu T, Jiang L, Wang X, Paulus YM. Long-term multimodal imaging characterization of persistent retinal neovascularization using DL-alpha-aminoadipic acid in pigmented and albino rabbit eyes. Experimental Eye Research 2021; 2076:108577.

  21. Everett L, Paulus YM. Laser therapy in the treatment of diabetic retinopathy and diabetic macular edema. Current Diabetes Reports 2021; 21(9):35. https://doi.org/10.1007/s11892-021-01403-6

  22. Xu G, Ni L, Reisterer J, Kim W, Wang H, Berry L, Zhang W, Paulus YM, Wang X, Moroi S, Argento A. Photoacoustic imaging and finite element strain analysis as novel tools for assessing the roles of aqueous veins and perilimbal sclera in intraocular pressure regulation. Proc. SPIE 11645, Optical Elastography and Tissue Biomechanics VIII, 1164509 (5 March 2021); https://doi.org/10.1117/12.2577878

  23. Xu G, Ni L, Reisterer J, Kim W, Wang H, Berry L, Zhang W, Paulus YM, Wang X, Moroi S, Argento A. Assessing the biomechanical behavior of aqueous veins and perilimbal sclera complex using photoacoustic imaging and finite element analysis. Proc. SPIE 11642, Photons Plus Ultrasound: Imaging and Sensing 2021, 116420Z (5 March 2021); https://doi.org/10.1117/12.2577829

  24. Nguyen VP, Folz J, Li Y, Henry J, Zhang W, Wang X, Paulus YM. High resolution photoacoustic microscopy molecular imaging of choroidal neovascularization using functionalized indocyanine green in living rabbits. Proc. SPIE 11631, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIX, 116310P (5 March 2021); https://doi.org/10.1117/12.2577692

  25. Nguyen VP, Li Y, Henry J, Aaberg M, Jones S, Qian T, Zhang W, Wang X, Paulus YM. In vivo three-dimensional visualization of choroidal neovascularization using gold nanorod-enhanced multimodal photoacoustic microscopy and optical coherence tomography molecular imaging. Proc. SPIE 11634, Multimodal Biomedical Imaging XVI, 1163404 (5 March 2021); https://doi.org/10.1117/12.2577669

  26. Nguyen VP, Li Y, Qian W, Liu B, Henry J, Zhang W, Wang X, Paulus YM. In vivo evaluation of retinal neovascularization using chain-like cluster gold nanoparticle-enhanced multimodal photoacoustic microscopy and optical coherence tomography molecular imaging. Proc. SPIE 11642, Photons Plus Ultrasound: Imaging and Sensing 2021, 116420H (5 March 2021); https://doi.org/10.1117/12.2577660

  27. Nguyen VP, Zhu T, Fan W, Qian W, Li Y, Zhang W, Henry J, Liu B, Wang X, Paulus YM. In vivo multimodal photoacoustic microscopy and optical coherence tomography longitudinal tracking of progenitor cells labeled with functionalized chain-like gold nanoparticle clusters after ocular subretinal transplantation. Proc. SPIE 11642, Photons Plus Ultrasound: Imaging and Sensing 2021, 116422R (5 March 2021); https://doi.org/10.1117/12.2577647

  28. Qin Y, Zhu Y, Yu Y, Paulus YM, Yang X, Wang X. Using a diagnostic ultrasound system for photo-mediated ultrasound therapy. Proc. SPIE 11642, Photons Plus Ultrasound: Imaging and Sensing 2021, 116422A (5 March 2021); https://doi.org/10.1117/12.2576602

  29. Zhang W, Li Y, Nguyen VP, Paulus YM, Wang X. Integrated simultaneous multimodality photoacoustic microscopy, optical coherence tomography, and fluorescence microscopy for rabbit ocular imaging in vivo and safety evaluation. Proc. SPIE 11623, Ophthalmic Technologies XXXI, 116230O (5 March 2021); https://doi.org/10.1117/12.2576600

  30. Qin Y, Yu Y, Fu J, Xie X, Wang T, Paulus YM, Yang X, Wang X. Photo-mediated ultrasound therapy for treatment of corneal neovascularization in rabbit eyes. Proc. SPIE 11623, Ophthalmic Technologies XXXI, 116231V (5 March 2021); https://doi.org/10.1117/12.2576595

  31. Li X, Zhang W, Li Y, Wu X, Paulus YM, Wang X, Fan X, Wang M, Tan X. In vivo single cell tracking of progenitor cells labeled with nanowire lasers using optical coherence tomography and fluorescence microscopy dual-modality imaging. Proc. SPIE 11634, Multimodal Biomedical Imaging XVI, 1163406 (5 March 2021); https://doi.org/10.1117/12.2576467

  32. Nguyen VP, Li Y, Henry J, Qian T, Zhang W, Wang X, Paulus YM. Gold nanorod enhanced Photoacoustic Microscopy and Optical Coherence Tomography of Choroidal Neovascularization. ACS Applied Materials and Interfaces 2021 Sep 1; 13(34): 40214-40228. doi: 10.1021/acsami.1c03504.

  33. Nguyen VP, Li Y, Henry J, Qian T, Zhang W, Wang X, Paulus YM. In vivo subretinal ARPE-19 cell tracking using indocyanine green contrast-enhanced multimodality photoacoustic microscopy, optical coherence tomography, and fluorescence imaging for regenerative medicine. Trans Vis Sci Technol 2021 Aug 12;10(10):10. doi: 10.1167/tvst.10.10.10.

  34. Nguyen VP, Fan W, Zhu T, Qian W, Li Y, Liu B, Zhang W, Henry J, Yuan S, Wang X, Paulus YM. Long-Term, Noninvasive In Vivo Tracking of Progenitor Cells Using Multimodality Photoacoustic, Optical Coherence Tomography, and Fluorescence Imaging. ACS Nano. 2021 Aug 11. 10.1021/acsnano.1c03035. doi: 10.1021/acsnano.1c03035. Online ahead of print.

  35. Nguyen VP, Qian W, Wang X, Paulus YM. Functionalized contrast agents for multimodality photoacoustic microscopy, optical coherence tomography, and fluorescence microscopy molecular retinal imaging. Methods Enzymol 2021;657:443-480. doi: 10.1016/bs.mie.2021.06.038.

  36. Yang X, Paulus YM, Wang X. Treatment of neovascularization in the eye by photo-mediated ultrasound therapy. The Journal of the Acoustical Society of America 2021;150(4), A167. https://doi.org/10.1121/10.0008005

  37. Chen J, Nguyen VP, Jaiswal S, Kang X, Lee M, Paulus YM, Wang TD. Thin layer-protected gold nanoparticles for targeted multimodal imaging with photoacoustic and CT. Pharmaceuticals (Basel). 2021;14(11):1075. http://doi.org/10.3390/ph14111075v

  38. Nguyen VP, Li Y, Henry J, Zhang W, Aaberg M, Jones S, Qian T, Wang X, Paulus YM. Plasmonic gold nanostar-enhanced multimodal photoacoustic microscopy and optical coherence tomography molecular imaging to evaluate choroidal neovascularization. ACS Sensors 2020 Oct 23; 5(10):3070-81. https://dx.doi.org/10.1021/acssensors.0c00908

  39. Qin Y, Yu Y, Xie X, Zhang W, Fu J, Paulus YM, Yang X, Wang X. The effect of laser and ultrasound synchronization in photo-mediated ultrasound therapy. IEEE Transactions on Biomedical Engineering 2020; 67 (12): 3363-70. doi: 10.1109/TBME.2020.2985648.

  40. Wu AM, Zhao PY, Wubben TJ, Hyde RA, Paulus YM, Johnson MW. Serology negative Bartonella neuroretinitis in an immunocompromised patient. Retinal Cases & Brief Reports 2020 Mar 3. doi: 10.1097/ICB.0000000000000995. Online ahead of print.

  41. Nguyen VP, Li Y, Zhang W, Henry J, Aaberg M, Wang X, Paulus YM. Gold nanostar-enhanced multimodal photoacoustic microscopy and optical coherence tomography for the visualization of laser-induced choroidal neovascularization in living rabbits. Proc. SPIE 11257, Plasmonics in Biology and Medicine XVII, 112570G (21 February 2020); doi: 10.1117/12.2543212

  42. Yu G, Aaberg MT, Patel TP, Iyengar RS, Powell C, Tran A, Miranda C, Young E, Demetriou K, Devisetty L, Paulus YM. Quantification of Retinal Nonperfusion and Neovascularization with Ultrawide-Field Fluorescein Angiography in Patients with Diabetes and Associated Characteristics of Advanced Disease. JAMA Ophthalmology 2020 Jun 1; 138(6):680-688. doi:10.1001/jamaophthalmol.2020.1257

  43. Wang M, Qin Y, Wang T, Orringer JS, Paulus YM, Yang X, Wang X. Removing subcutaneous microvessels using photo-mediated ultrasound therapy. Lasers in Surgery & Medicine 2020 Dec;52(10):984-992. doi: 10.1002/lsm.23260.. https://doi.org/10.1002/lsm.23260

  44. Zhang W, Li Y, Nguyen VP, Derouin K, Xia X, Paulus YM, Wang X. Ultra-low energy photoacoustic microscopy for ocular imaging in vivo. Journal of Biomedical Optics 2020 Jun; 25(6):1-8. doi: 10.1117/1.JBO.25.6.066003.

  45. Zhang W, Li Y, Yu Y, Derouin K, Qin Y, Nguyen VP, Xia X, Wang X, Paulus YM. Simultaneous photoacoustic microscopy, spectral-domain optical coherence tomography, and fluorescein microscopy multi-modality retinal imaging. Photoacoustics 2020 Jun 6; 20: 100194. https://doi.org/10.1016/j.pacs.2020.100194

  46. Li X, Zhang W, Wang WY, Wu X, Li Y, Tan X, Matera DL, Baker BM, Paulus YM, Fan X, Wang X. Optical coherence tomography and fluorescence microscopy dual-modality imaging for in vivo single-cell tracking with nanowire lasers. Biomedical Optics Express 2020 Jun 9;11(7): 3659-3672. https://doi.org/10.1364/BOE.395369

  47. Paulus YM, Qin Y, Yu Y, Fu J, Wang X, Yang X. Photo-mediated Ultrasound Therapy to Treat Retinal Neovascularization. IEEE Engineering in Medicine & Biology Society (EMBC) 2020 July: 5244-7. doi: 10.1109/EMBC44109.2020.9175882. PMID: 33019167

  48. Nguyen VP, Li Y, Henry J, Zhang W, Wang X, Paulus YM. High Resolution Multimodal Photoacoustic Microscopy and Optical Coherence Tomography Visualization of Choroidal Vascular Occlusion. International Journal of Molecular Sciences 2020 Sep 5;21(18):6508. doi: 10.3390/ijms21186508.

  49. Jairath N, Commiskey P, Kaplan A, Paulus YM. FLASH: A Novel Tool to Identify Vision-Threating Eye Emergencies. Int. J. Ophthalmic Res 2020 September; 6(1): 321-328. DOI: 10.17554/j.issn.2409-5680.2020.06.91

  50. Qiu A, Yu Y, Huang J, Liu Q, Paulus YM, Fan W. A PRPH2 Gene Variant Detected in Retinitis Punctata Albescens with Congenital Hypertrophy of the Retinal Pigment Epithelium. European Journal of Ophthalmology 2020. https://doi.org/10.1177/1120672120962027

  51. Nguyen VP, Fan W, Li Y, Henry J, Aaberg M, Zhang W, Wang X, Paulus YM. Multimodal photoacoustic microscopy and optical coherence tomography imaging of laser-induced choroidal neovascularization in the rabbit retina. Proc. SPIE 11218, Ophthalmic Technologies XXX, 1121825 (19 February 2020); doi: 10.1117/12.2543219

  52. Nguyen VP, Li Y, Henry J, Aaberg M, Jones S, Qian T, Zhang W, Wang X, Paulus YM. Near-infrared fluorophore capped gold nanostars for enhanced detection of choroidal neovascularization in living rabbits using multimodal photoacoustic microscopy, optical coherence tomography, and fluorescence microscopy. Proc. SPIE 11232, Multimodal Biomedical Imaging XV, 1123203 (17 February 2020); doi: 10.1117/12.2543214

  53. Nguyen VP, Li Y, Qian W, Liu B, Henry J, Aaberg M, Jones S, Qian T, Zhang W, Wang X, Paulus YM. Clusters gold nanoparticle-enhanced multimodal photoacoustic microscopy and optical coherence tomography for the identification of choroidal neovascularization in living rabbits. Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 112403W (17 February 2020); doi: 10.1117/12.2543208

  54. Nguyen VP, Paulus YM. Photoacoustic Microscopy of the Retina and Choroid. Retinal Physician 2020 Jan; 42-47.

  55. Nguyen VP, Fan W, Li Y, Henry J, Aaberg M, Zhang W, Wang X, Paulus YM. Multimodal photoacoustic microscopy and optical coherence tomography imaging of laser-induced choroidal neovascularization in the rabbit retina. Proc. SPIE 11218, Ophthalmic Technologies XXX, 1121825 (19 February 2020); doi: 10.1117/12.2543219

  56. Nguyen VP, Li Y, Qiao W, Liu B, Tian C, Zhang W, Huang Z, Ponduri A, Tarnowski M, Wang X, Paulus YM. Contrast Agent Enhanced Multimodal Photoacoustic Microscopy and Optical Coherence Tomography for Imaging of Rabbit Choroidal and Retinal Vessels in vivo. Scientific Reports 2019; 9(1):5945.

  57. Patel TP, Kim TN, Yu G, Dedania VS, Lieu P, Qian CX, Besirli CG, Demirci H, Margolis T, Fletcher DA, Paulus YM. Smartphone-based, rapid, wide-field fundus photography for diagnosis of pediatric retinal diseases. Trans Vis Sci Tech 2019; 8(3):29, https://doi.org/10.1167/tvst.8.3.29

  58. Li Y, Zhang W, Nguyen VP, Rosen R, Wang X, Xia X, Paulus YM. Real-time OCT guidance and multimodal imaging monitoring of subretinal injection induced choroidal neovascularization in rabbit eyes. Experimental Eye Research 2019;186:107714

  59. Nguyen VP, Li Y, Zhang W, Wang X, Paulus YM. High-resolution multimodal photoacoustic microscopy and optical coherence tomography image-guided laser induced branch retinal vein occlusion in living rabbits. Scientific Reports 2019; 9(1):10560

  60. Zhang W, Qin Y, Xie X, Hu Z, Paulus YM, Yang X, Wang X. Real-time Photoacoustic Sensing for Photo-mediated Ultrasound Therapy. Optics Letters 2019; 44(16): 4063-66.

  61. Patel TP, Aaberg MT, Paulus YM, Lieu P, Dedania VS, Qian CX, Besirli CG, Margolis T, Fletcher DA, Kim TN. Smartphone-based fundus photography for screening of plus-disease retinopathy of prematurity. Graefes Arch Clin Exp Ophthalmol. 2019;257(11):2579-2585.

  62. Wubben TJ, Johnson MW, Anti-VEGF Treatment Interruption Study Group: Sohn EH, Peairs JJ, Kay C, Kim SJ, Gardner TW, Paulus YM, Zacks DN, Steinle NC, Avery RL, Berrocal MH. Anti-VEGF Therapy for Diabetic Retinopathy: Consequences of Inadvertent Treatment Interruptions. Am J Ophthalmol 2019; 204:13-18.

  63. Li P, Paulus YM, Davila JR, Gosbee J, Kim T. Usability testing of a smartphone-based retinal camera among first-time users in the primary care setting. BMJ Innovations 2019; 5: 120-6. doi: 10.1136/bmjinnov-2018-000321

  64. Nguyen VP, Li Y, Qian W, Liu B, Tian C, Zhang W, Huang Z, Henry J, Rosen R, Aaberg M, Ponduri A, Tarnowski M, Wang X, Paulus YM. Contrast agent enhanced multimodal photoacoustic microscopy and optical coherence tomography for imaging rabbit choroidal and retinal vessels in vivo. Proc. SPIE 10868, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVII, 1086806 (26 February 2019); doi: 10.1117/12.2510756

  65. Nguyen VP, Li Y, Henry J, Rosen R, Aaberg M, Zhang W, Wang X, Paulus YM. Integrated photoacoustic microscopy and optical coherence tomography image-guided laser induced branch retinal vein occlusion in living rabbits. Proc. SPIE 10871, Multimodal Biomedical Imaging XIV, 1087104 (27 February 2019); doi: 10.1117/12.2510720

  66. Commiskey PW, Heisel CJ, Paulus YM. Non-Therapeutic Laser Retinal Injury. Int. J. Ophthalmic Res 2019; 5(1): 321-335.

  67. Nguyen VP, Li Y, Henry J, Aaberg M, Rosen R, Jones S, Zhang W, Wang X, Paulus YM. Multi-wavelength photoacoustic microscopy for detection of retinal vein occlusion during laser photocoagulation in rabbits. Proc. SPIE 10890, Label-free Biomedical Imaging and Sensing (LBIS) 2019, 108902N (4 March 2019); doi:10.1117/12.2510777

  68. Sassalos TM, Paulus YM. Prefilled syringes for intravitreal drug delivery. Clinical Ophthalmology 2019:13, 1–6.

  69. Zhang W, Li Y, Nguyen VP, Huang Z, Liu Z, Wang X, Paulus YM. High resolution, in vivo Multimodal Photoacoustic Microscopy, Optical Coherence Tomography, and Fluorescence Microscopy Imaging of Rabbit Retinal Neovascularization. Light: Science & Applications 2018; 7:103.

  70. Nguyen VP, Li Y, Aaberg M, Zhang W, Wang X, Paulus YM. In vivo 3D imaging of retinal neovascularization using multimodal photoacoustic microscopy and optical coherence tomography imaging. Journal of Imaging 2018; 4: 150. doi:10.3390/jimaging4120150

  71. Nguyen VP, Paulus YM. Photoacoustic Ophthalmoscopy: Principle, Application, and Future Directions. Journal of Imaging 2018; 4: 149. doi:10.3390/jimaging4120149

  72. Tian C, Paulus YM. Photoacoustic Microscopy Imaging of the Eye. Optics & Photonics News 2018 Dec; 12: 50.

  73. Nguyen VP, Li Y, Zhang W, Wang X, Paulus YM. Multi-wavelength, en-face Photoacoustic Microscopy and Optical Coherence Tomography Imaging for Early and Selective Detection of Laser Induced Retinal Vein Occlusion. Biomedical Optics Express 2018; 9(12): 5915-5938. https://doi.org/10.1364/BOE.9.005915

  74. Kim TN, Myers F, Reber C, Loury PJ, Loumou P, Webster D, Echanique C, Li P, Davila JR, Maamari RN, Switz NA, Keenan J, Woodward MA, Paulus YM, Margolis T, Fletcher DA. A smartphone-based tool for rapid, portable, and automated wide-field retinal imaging. Transl Vis Sci Technol 2018; 7(5):21. doi: 10.1167/tvst.7.5.21.

  75. Zhang H, Xie X, Li J, Qin Y, Zhang W, Cheng Q, Yuan S, Liu Q, Paulus YM, Wang X, Yang X. Removal of choroidal vasculature using concurrently applied ultrasound burst and nanosecond laser pulses. Scientific Reports 2018; 8:12848. DOI:10.1038/s41598-018-31045-w.

  76. Paulus YM, Belill N. Preretinal Hemorrhages Following Chiropractor Neck Manipulation. American Journal of Ophthalmology Case Reports 2018; 11:181-3. doi: 10.1016/j.ajoc.2018.04.017.

  77. Tian C, Zhang W, Phuc VP, Wang X, Paulus YM. Novel Photoacoustic Microscopy and Optical Coherence Tomography Dual-modality Chorioretinal Imaging in Living Rabbit Eyes. Journal of Visualized Experiments 2018; 132: e57135. doi:10.3791/57135

  78. Li J, Paulus YM. Advances in Retinal Laser Therapy. International Journal of Ophthalmic Research 2018; 4(1): 1-6.

  79. Tian C, Zhang W, Nguyen VP, Huang Z, Wang X, Paulus YM. Retinal and choroidal imaging in vivo using integrated photoacoustic microscopy and optical coherence tomography. Proc. SPIE 10474, Ophthalmic Technologies XXVIII, 104741E (19 February 2018).

  80. Tian C, Zhang W, Nguyen VP, Huang Z, Wang X, Paulus YM. Integrated photoacoustic microscopy, optical coherence tomography, and fluorescence microscopy for multimodal chorioretinal imaging. Proc. SPIE 10494, Photons Plus Ultrasound: Imaging and Sensing 2018, 104945U (19 February 2018).

  81. Li Y, Xia X, Paulus YM. Advances in Retinal Optical Imaging. Photonics 2018; 5, 9; doi:10.3390/photonics5020009.

  82. Xie X, Liu Q, Paulus YM. Innovations in Retinal Laser Technology. Optics and Photonics Journal 2018; 8(6): 173-186. doi: 10.4236/opj.2018.86016.

  83. Xie X, Liu Q, Paulus YM. Novel Retinal Laser Therapies. International Journal of Ophthalmic Research 2018; 4(1): 272-279.

  84. Thomas M, Rao R, Johnson M, Paulus YM. Re: Bressler SB, et al.: Factors Associated with Worsening Proliferative Diabetic Retinopathy in Eyes Treated with Panretinal Photocoagulation or Ranibizumab. Ophthalmology 2017 Dec; 124(12): e87-e88.

  85. Paulus YM, Leung L-S, Pilyugina S, Blumenkranz MS. Comparison of pneumatic retinopexy and scleral buckle for primary rhegmatogenous retinal detachment repair. Ophthalmic Surg Lasers Imaging Retina 2017 Nov 1;48(11):887-893.

  86. Zhang H, Xie X, Wang X, Yang X, Paulus YM. Photomediated Ultrasound Therapy Offers Precision Targeting of Microvessels. BioPhotonics 2017; 24(8): 19-23.

  87. Li Y, Xia X, Paulus YM. Novel Retinal Imaging Technologies. International Journal of Ophthalmology & Eye Science 2017; 5(7):329-333.

  88. Tian C, Zhang W, Mordovanakis A, Wang X, Paulus YM. Noninvasive chorioretinal imaging in living rabbits using integrated photoacoustic microscopy and optical coherence tomography. Optics Express 2017; 25(14): 15947-55.

  89. Paulus YM, Jefferys J, Hawkins BS, Scott AW. Visual Function Quality of Life Measure Changes Upon Conversion to Neovascular Age-Related Macular Degeneration in Second Eyes. Quality of Life Research 2017;26(8):2139-2151.

  90. Li J, Paulus YM, Shuai Y, Fang W, Liu Q, Yuan S. New Developments in the Classification, Pathogenesis, Risk Factors, Natural History and Treatment of Branch Retinal Vein Occlusion. Journal of Ophthalmology (2017); 2017:4936924.

  91. Gaynon MW, Paulus YM, Rahimy E, Alexander JL, Mansour SE. Effect of Oral Niacin on Central Retinal Vein Occlusion. Graefe's Archive for Clinical and Experimental Ophthalmology 2017;255(6):1085-1092.

  92. Hu Z, Zhang H, Mordovanakis A, Paulus YM, Liu Q, Wang X, Yang X. High-precision, non-invasive anti-microvascular approach via concurrent ultrasound and laser irradiation. Scientific Reports 2017 Jan 11;7:40243.

  93. Hu Z, Liu Q, Paulus YM. New Frontiers in Retinal Imaging. International Journal of Ophthalmic Research 2016; 2(3): 148-58.

  94. Paulus YM, Butler NJ. Wide Field Photography, Optical Coherence Tomography, and Fundus Autofluorescence Correlation of Posterior Ophthalmomyiasis Interna. OSLI Retina 2016; 47(7):682-5.

  95. Sen D, SoRelle ED, Liba O, Dalal R, Paulus YM, Kim T-W, Moshfeghi DM, de la Zerda A. High resolution contrast-enhanced Optical Coherence Tomography in mice retinae. Journal of Biomedical Optics 2016; 21(6): 066002.

  96. Rahimy E, Gaynon MW, Paulus YM, Alexander JL, Mansour SE. Potentially Reversible Effect of Niacin Therapy on Edema from Retinal Vein Occlusion. JAMA Ophthalmology 2016; 134(7):839-40.

  97. Paulus YM, Johnson MW. Further Evidence that Cataract Surgery is not Associated with Macular Degeneration Progression. JAMA Ophthalmology 2016; 134(6): 627.

  98. Paulus YM, Cheng S, Karth PA, Leng T. Prospective Trial of Endogenous Fungal Endophthalmitis and Chorioretinitis Rates, Clinical Course, and Outcomes in Patients with Fungemia. RETINA 2016; 36(7):1357-63.

  99. Paulus YM, Wenick AS. Development of Chronic Subretinal Fluid in Kearns-Sayre Syndrome. Retinal Cases & Brief Reports 2016; 10(3):236-8.

  100.   Paulus YM, Campbell JP. Neuroprotection and Retinal Diseases. Developments in Ophthalmology 2016; 55:322-9.

  101.   Campochiaro PA, Hafiz G, Mir TA, Scott AW, Sophie R, Shah SM, Ying HS, Lu L, Chen C, Campbell JP, Kherani S, Zimmer-Galler I, Wenick A, Han I, Paulus Y, Sodhi A, Wang G, Qian J. Reply Pro-permeability Factors After Dexamethasone Implant in Retinal Vein Occlusion; The Ozurdex for Retinal Vein Occlusion (ORVO) Study. Am J Ophthalmol 2016; 161:216-7.

  102.   Hu Z, Wang X, Liu Q, Paulus YM. Photoacoustic Imaging in Ophthalmology. International Journal of Ophthalmology & Eye Science 2015; 3(8): 126-132.

  103.   Paulus YM, Kuo C-H, Morohoshi K, Nugent A, Zheng LL, Nomoto H, Blumenkranz MS, Palanker D, Ono SJ. Serum Inflammatory Markers after Rupture Retinal Laser Injury in Mice. Ophthalmic Surgery, Lasers & Imaging Retina 2015; 46(3):362-8.

  104.   Paulus YM, Alcorn DM, Gaynon M, Moshfeghi DM. Peripheral Avascular Retina Term Male with Microvillus Inclusion Disease and Pancreatic Insufficiency. Ophthalmic Surgery, Lasers & Imaging Retina 2015; 46(5): 589-591.

  105.   Paulus YM. New Frontiers in Selective Retinal Lasers. International Journal of Ophthalmic Research 2015; 1(1):1-4.

  106.   Campochiaro PA, Hafiz G, Mir TA, Scott AW, Sophie R, Shah SM, Ying HS, Lu L, Chen C, Campbell JP, Kherani S, Zimmer-Galler I, Wenick A, Han I, Paulus Y, Sodhi A, Wang G, Qian J. Pro-permeability Factors after Dexamethasone Implant in Retinal Vein Occlusion; the Ozurdex for Retinal Vein Occlusion (ORVO) Study. Am J Ophthalmol 2015; 160(2): 313-321.

  107.  Naik NA, Paulus YM, Moshfeghi DM. Bilateral Extramacular Choroidal Neovascularization in Wet Age-Related Macular Degeneration. SM Ophthalmology Journal 2015; 1(1):1004.

  108.   Paulus YM, Riedel ER, Sabra MM, Tuttle RM, Kalin MF. Prevalence of Diabetes Mellitus in Patients with Newly Evaluated Papillary Thyroid Cancer. Thyroid Research 2014; 7:7.

  109.   Paulus YM, Wong IG, Sanislo S, Moshfeghi DM. Prefoveal Vitreous Condensation in Chronic Inflammation. Ophthalmic Surgery, Lasers & Imaging Retina 2014; 45(5): 447-50.

  110.   Siddiqui AA, Paulus YM, Scott AW. Fundus Autofluorescence to Identify Plaques and Diagnose and Follow Branch Retinal Artery Occlusions. Retina 2014; 34(12): 2490-1.

  111.   Nugent AK, Paulus YM, Chan A, Kim JW, Schwartz EJ, Moshfeghi DM. Multiple Myeloma Recurrence with Optic Nerve Infiltration Diagnosed by Vitrectomy, Immunohistochemistry, and in-situ Hybridization. European Journal of Ophthalmology 2014; 24(3):446-8.

  112.   Paulus YM, Bressler NM. Spontaneous Improvement in Myopic Foveoschisis. Eye 2014; 28(12):1519-20.

  113.   Paulus YM, Kaur K, Egbert PR, Blumenkranz MS, Moshfeghi DM. Human Histopathology of PASCAL Laser Burns. Eye 2013; 27(8): 995-6.

  114.   Paulus YM, Moshfeghi DM. Persistent Plus Disease after Laser in Retinopathy of Prematurity with Tetralogy of Fallot. European Journal of Ophthalmology 2013; 23(5): 764-6.

  115.   Paulus YM, Cockerham GC. Abiotrophia defectiva Causing Infectious Crystalline Keratopathy and Corneal Ulcer after Penetrating Keratoplasty: A Case Report. Journal of Ophthalmic Inflammation and Infection 2013; 3(20): 1-3.

  116.   Sher A, Jones BW, Huie P, Paulus YM, Lavinsky D, Leung LS, Nomoto H, Beier C, Marc RE, Palanker D. Restoration of Retinal Structure and Function after Selective Photocoagulation. The Journal of Neuroscience 2013; 33(16): 6800-8.

  117.   Nomoto H, Lavinsky D, Paulus YM, Leung L-S, Dalal R, Blumenkranz MS, Palanker D. Effect of Intravitreal Triamcinolone Acetonide on Healing of Retinal Photocoagulation Lesions. Retina 2013; 33 (1): 63-70.

  118.   Wang J, Sramek C, Paulus YM, Lavinsky D, Schuele G, Anderson D, Dewey D, Palanker DV. Ocular safety limits for 1030nm femtosecond laser cataract surgery. In Ophthalmic Technologies XXIII, Ed Fabrice Manns, Per G. Söderberg, Arthur Ho, Proceedings of SPIE 2013; Vol. 8567 (SPIE, Bellingham, WA), 856708.

  119.   Liu B, Hunter D, Rooker S, Chan A, Paulus YM, Leucht P, Nusse Y, Nomoto H, Helms J. Wnt signaling promotes Muller cell proliferation and survival after injury. The Investigative Ophthalmology & Visual Science (IOVS) 2013; 54(1): 444-53.

  120.   Paulus YM, Cockerham KP, Cockerham GC, Gratzinger D. IgG4-positive Sclerosing Orbital Inflammation Involving the Conjunctiva: A Case Report. Ocular Immunology and Inflammation 2012; 20(5): 375-377.

  121.   Paulus YM, Thompson NP. Inexpensive, Realtime Tele-ultrasound Using a commercial, web-based Video Streaming System. Journal of Telemedicine and Telecare 2012; 18(4): 185-8.

  122.   Brodie S, Paulus YM, Patel M, Gobin PY, Dunkel IJ, Marr B, Abramson DH. ERG monitoring of retinal function during systemic chemotherapy for retinoblastoma. British Journal of Ophthalmology 2012; 96(6): 877-80.

  123.   Sramek C, Leung L-S, Paulus YM, Palanker DV. Therapeutic window of retinal photocoagulation with green (532 nm) and yellow (577 nm) lasers. Ophthalmic Surgery Lasers, and Imaging 2012; 43(4): 341-7.

  124.   Wang J, Sramek C, Paulus YM, Lavinsky D, Schuele G, Anderson D, Dewey D, Palanker D. Retinal Safety of Near-Infrared Lasers in Cataract Surgery. Journal of Biomedical Optics 2012; 17 (9): 95001-1.

  125.   Leng T, Jaben KA, Zheng L, Yang J, Paulus YM, Moshfeghi AA, Maltenfort MG, Campbell PG, Ratliff JK, Moshfeghi DM. The influence of medical school and residency training program upon choice of an academic career and academic productivity among otolaryngology faculty in the United States: Our experience of 1433 academic otolaryngologists. Clin Otolaryngol 2012; 37(1): 58-62.

  126.   Paulus YM, Jain A, Nomoto H, Sramek C, Gariano RF, Andersen D, Schuele G, Leung L, Leng T, Palanker D. Selective Retinal Therapy with Microsecond Exposures using a Continuous Line Scanning Laser. Retina 2011; 31(2): 380-8.

  127.   Patel M, Paulus YM, Gobin YP, Djaballah H, Marr B, Dunkel IJ, Brodie S, Antczak C, Folberg R, Abramson DH. Intraarterial and Oral Digoxin Therapy for Retinoblastoma. Ophthalmic Genetics 2011; 32(3): 147-50.

  128.   Paulus YM, Sramek C, Blumenkranz MS, Palanker D. New Horizons in Retinal Laser Treatment: Sublethal Retinal Laser Therapy. Retinal Physician 2011; 8(2): 23 – 27.

  129.   Sramek C, Leung L-S, Leng T, Brown J, Paulus YM, Schuele G, Palanker D. Improving the therapeutic window of retinal photocoagulation by spatial and temporal modulation of the laser beam. Journal of Biomedical Optics 2011; 16(2): 028004.

  130.   Paulus YM, Wong AE, Chen B, Jacobson MT. Preputial Epidermoid Cyst: An Atypical Case of Acquired Pseudoclitoromegaly. Journal of Lower Genital Tract Disease 2010; 14(4), 382-386.

  131.   Paulus YM, Palanker D, Blumenkranz MS. Short-Pulse Laser Treatment: Redefining Retinal Therapy. Retinal Physician 2010; 7(1): 54, 56-59.

  132.   Paulus YM, Jain A, Gariano RF, Nomoto H, Schuele G, Sramek C, Charalel R, Palanker D. Selective Retinal Therapy with a Continuous Line Scanning Laser. In Ophthalmic Technologies XX, Ed Fabrice Manns, Per G. Söderberg, Arthur Ho, Proceedings of SPIE 2010; Vol. 7550 (SPIE, Bellingham, WA), 7550-0W-1 – 11.

  133.   de la Zerda A, Paulus YM, Teed R, Bodapati S, Dollberg Y, Khuri-Yakub, BT, Blumenkranz, MS, Moshfeghi DM, Gambhir SS. Photoacoustic Ocular Imaging. Optics Letters 2010; 35(3): 270 – 272.

  134.   Sramek C, Brown J, Paulus YM, Nomoto H, Palanker D. Improved Safety of Retinal Photocoagulation with a Shaped Beam and Modulated Pulse. In Ophthalmic Technologies XX, Ed Fabrice Manns, Per G. Söderberg, Arthur Ho, Proceedings of SPIE 2010; Vol. 7550 (SPIE, Bellingham, WA), 7550-0V-1 – 10.

  135.   Paulus YM, Jain A, Moshfeghi DM. Resolution of Persistent Exudative Retinal Detachment in a case of Sturge-Weber Due with Anti-VEGF Administration. Ocular Immunology and Inflammation 2009; 17(4): 292-294.

  136.   Sramek C, Paulus YM, Nomoto H, Huie P, Brown J, Palanker D. Dynamics of retinal photocoagulation and rupture. Journal of Biomedical Optics 2009 4(3): 034007.

  137.   Paulus YM, Gariano RF. Diabetic Retinopathy: A Growing Concern in an Aging Population. Geriatrics 2009; 64(2): 16-20.

  138.   Paulus YM, T. Sanger. Cerebral Aspergillosis in a Pediatric Case of Systemic Lupus Erythematosus. H&P: The Stanford Medical Student Journal 2009; 13(3): 4-7.

  139.   Sramek C, Paulus YM, Nomoto H, Huie P, Palanker D. Finite Element Model of Thermal Processes in Retinal Photocoagulation. In Optical Interactions with Tissue and Cells XX, Ed Steven L. Jacques, E. Duco Jansen, William P. Roach, Proceedings of SPIE 2009; Vol. 7175 (SPIE, Bellingham, WA) 7175-1F.

  140.   Sramek C, Paulus YM, Nomoto H, Huie P, Palanker D. Computational Model of Retinal Photocoagulation and Rupture. In Ophthalmic Technologies XIX, Ed Fabrice Manns, Per G. Söderberg, Arthur Ho, Proceedings of SPIE 2009; Vol. 7163 (SPIE, Bellingham, WA), 7163-0T

  141.   Paulus YM, Jain A, Gariano RF, Stanzel BV, Marmor M, Blumenkranz MS, Palanker D. Healing of Retinal Photocoagulation Lesions. Investigative Ophthalmology & Visual Science (IOVS) 2008; 49(12): 5540-5545.

  142.   Jain A, Blumenkranz MS, Paulus YM, Wiltberger MW, Andersen DE, Huie P, Palanker D. Effect of Pulse Duration on Size and Character of the Lesion in Retinal Photocoagulation. Archives of Ophthalmology 2008; 126 (1): 78-85.

  143.   Palanker D, Paulus YM, Jain A, Huie P, Andersen D, Stanzel BV, Marmor MF, Blumenkranz MS. Minimally-traumatic Retinal Photocoagulation. In Ophthalmic Technologies XVIII, Ed Fabrice Manns, Per G. Söderberg, Arthur Ho, Proceedings of SPIE; 2008, Vol. 6844 (SPIE, Bellingham, WA), 6844-A31.

  144.   Poulaki V, Iliaki E, Mitsiades NS, Mitsiades CS, Paulus YM, Bula D, Gragoudas ES, Miller JW. Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis. The FASEB (Federation of American Societies for Experimental Biology) Journal 2007; 21 (9): 2113-23.

  145.   Palanker D, Jain A, Paulus YM, Andersen D, Blumenkranz M. Patterned Retinal Coagulation with a Scanning Laser. In Ophthalmic Technologies XVII, Ed Fabrice Manns, Per G. Söderberg, Arthur Ho, Proceedings of SPIE 2007; Vol. 6426 (SPIE, Bellingham, WA), 6426-1E.

Book Chapters

  1. Li Y, Paulus YM. Photoacoustic Imaging of the Eye. In Photoacoustic Imaging - Principles, Advances and Applications. London, UK: IntechOpen, 2019. DOI: 10.5772/intechopen.86050

  2. Fan W, Paulus YM. Scleral Buckle for Repair of Retinal Detachment. Leon V. Berhardt, Ed. In Advances in Medicine and Biology. Volume 154. Hauppauge, NY: Nova Science Publishers Inc, 2019.

  3. Paulus YM, Blumenkranz MS. Chapter 39: Laser for Vitreoretinal Diseases. In Vitreoretinal Disease: The Essentials, 2e. Scott IU, Regillo CD, Flynn HW, Brown GC, eds. New York, NY: Thieme Medical Publishers, 2018.

  4. Paulus YM, Sodhi A. “Anti-angiogenic Therapy for Retinal Disease.” In Handbook of Experimental Pharmacology. Switzerland: Springer International Publishing, 2017; 242: 271-307.

  5. Paulus YM, Campbell JP. Neuroprotection and Retinal Diseases. In Retinal Pharmacotherapeutics. Developments in Ophthalmology. Nguyen QD, Rodrigues EB, Farah ME, Mieler WF, Do DV (eds). Basel: Karger, 2016; 55: 322-9.

  6. Lad EM, Koreen L, Pecen P, Vickers L, Meetu P, Paulus YM, Nguyen C, Kim MJ. Medical Retina. In The Ophthalmology Clinical Trials Handbook. New York, NY: Nova Biomedical, 2015.

  7. Paulus YM, Ta CN. Ocular Antibiotics. In Copeland and Afshari Principles and Practice of Cornea. New Delhi, India: Jaypee Brothers Medical Publisher, 2012.

  8. Jain A, Paulus YM, Cockerham GC, Kenyon KR. Keratoconus and Other Non- inflammatory Thinning Conditions. Duane's Foundations of Clinical Ophthalmology Vol 4, Chapter 16C. Ed. William Tasman, MD and Edward A. Jaeger, MD. Philadelphia: Lippincott Williams and Wilkens, 2008. Oct 1, 2008 http://duanessolution.com

Letters/Editorials

1. Campochiaro PA, Hafiz G, Mir TA, Scott AW, Sophie R, Shah SM, Ying HS, Lu L, Chen C, Campbell JP, Kherani S, Zimmer-Galler I, Wenick A, Han I, Paulus Y, Sodhi A, Wang G, Qian J. Reply Pro-permeability Factors After Dexamethasone Implant in Retinal Vein Occlusion; The Ozurdex for Retinal Vein Occlusion (ORVO) Study. Am J Ophthalmol 2016; 161:216-7.

2. Paulus YM, Johnson MW. Further Evidence that Cataract Surgery is not Associated with Macular Degeneration Progression. JAMA Ophthalmology 2016 Jun 1; 134(6): 627.

3. Thomas M, Rao R, Johnson M, Paulus YM. Re: Bressler SB, et al.: Factors Associated with Worsening Proliferative Diabetic Retinopathy in Eyes Treated with Panretinal Photocoagulation or Ranibizumab. Ophthalmology 2017 Dec; 124(12): e87-e88.

4. Nguyen VP, Li Y, Zhang W, Wang X, Paulus YM. Author Correction: High-resolution multimodal photoacoustic microscopy and optical coherence tomography image-guided laser induced branch retinal vein occlusion in living rabbits. Sci Rep. 2020 Mar 3;10(1):4264. doi: 10.1038/s41598-020-60919-1.