Mammalian Work
The mammalian component animal module provides state of the art operating rooms and visual testing equipment within the Wilmer/Woods animal colony. The shared equipment is critical to the research being conducted by many investigators here at Wilmer. The animal module facilities allow researchers to extend basic science into animal models, monitor disease progression in these models and test therapies. Drs. Edwards and Bhutto will provide training on use of Core equipment as well as authorizing access to the facility.
Access instructions should be on the about page or maybe the main page.
For access to Wilmer/Woods facilities, researchers first need training from RAR: Research Animal Resources (jhu.edu)
For access to the operating rooms and equipment, the following form must be completed and signed by Drs. Malia Edwards or Imran Bhutto.
Labs wishing to request Animal Facility access or change existing access must fill out the application.
Access the reservation calendar
Contact for Access to ORs and Equipment Training
Dr. Malia Edwards
M023 Smith Building
Phone: 410-614-9888
Email: [email protected]
Zebrafish Module
Zebrafish have emerged as a premier animal model system. They are particularly well suited to developmental and regenerative biology, disease modeling, large-scale genetic and chemical screening, and intravital 4D imaging of dynamic biological processes. Recent contributions to vision research include: identification of Muller glia as injury-responsive retinal stem cells; high-resolution 3D mapping of visual neural circuitry, identification of retinal degeneration mutants; and delineation of key roles for retinal microglia in regulating retinal regeneration. The Animal Core assists JHU researchers in integrating zebrafish into their vision research program. Services include: efficient genome modification (e.g., transgenesis, knockouts, knock ins), visual behavior assays (e.g., VMR, OMR, OKR, prey capture), and a novel high-throughput phenotypic screening (HPS) platform enabling large-scale drug discovery in living disease models.