Find a Research Lab

Research Lab Results

Results per page:

  • The James Laboratory

    The James Laboratory studies mechanisms of bone repair, development, and neoplasia.
    Lab Website

    Principal Investigator

    Aaron James, MD PhD

    Department

    Pathology

  • Early Detection of Pancreatic Cancer Laboratory

    The goal of the lab's research is to identify molecular abnormalities that can improve the outcome of patients with pancreatic cancer and those at risk of developing this disease. Much of our work is focused on translational research evaluating markers and marker technologies that can help screen patients with an increased risk of developing pancreatic cancer. Thus, marker efforts have been focused mostly on identifying markers of advanced precancerous neoplasia (PanINs and IPMNs) that could improve our ability to effectively screen patients at risk of developing pancreatic cancer. We lead or participate in a number of clinical research protocols involved in the screening and early detection of pancreatic neoplasia including the CAPS clinical trials. We maintain a large repository of specimens from cases and controls with and without pancreatic disease and use this repository to investigate candidate markers of pancreatic cancer for their utility to predict pancreatic cancer risk. In addition, we have been working to identify familial pancreatic cancer susceptibility genes and identified BRCA2 as a pancreatic cancer susceptibility gene in 1996. We participate in the PACGENE consortium and the familial pancreatic cancer sequencing initiative. My lab also investigates pancreatic cancer genetics, epigenetics, molecular pathology, tumor stromal interactions and functional analysis of candidate genes and miRNAs. Dr. Goggins is the principal investigator of a phase I/II clinical trial evaluating the Parp inhibitor, olaparib along with irinotecan and cisplatin for patients with pancreatic cancer.

    Principal Investigator

    Michael G. Goggins, MD

    Department

    Medicine

    Oncology

    Pathology

    Research Areas

  • Eun Ji Shin Lab

    Research interests in the Eun Ji Shin Lab include clinical research on obesity and the effect on GI neoplasia/malignancy.

    Principal Investigator

    Eun Ji Shin, MD

    Department

    Medicine