Research in Brachytherapy and Radiopharmaceutical Therapy

Brachytherapy automation

We develop and translate automation tools for imaging, treatment planning, quality assurance, and outcome analysis for brachytherapy to improve its accuracy, efficiency and safety.

Radiopharmaceutical Therapy

We use radiopharmaceuticals that selectively bind to specific proteins or molecules on cancer cells, allowing the radioactive particles to be delivered directly to the tumor while sparing surrounding healthy tissues. We explore the use of radiopharmaceuticals in combination with other treatments, such as chemotherapy, radiation therapy, and immunotherapy, to improve treatment efficacy and minimize toxicity.

Imaging and image-guidance techniques

We develop new imaging techniques, such as positron emission tomography (PET) and single photon emission computed tomography (SPECT), to support accurate patient-specific radiation dose calculation, monitor treatment response and optimize treatment protocols in radiopharmaceutical therapy. We employ novel imaging techniques such as real-time MR imaging to guide brachytherapy procedures to precise applicator insertion and automatic treatment planning.

Core Faculty

  • Kai Ding

    Associate Professor
    kai@jhu.edu
    Lab: https://dinglab.jh.edu/

    Kai Ding
  • Rob Hobbs

    Associate Professor
    rhobbs3@jhmi.edu

    Rob Hobbs
  • Xun Jia

    Professor
    Chief of Medical Physics Division
    xunjia@jhu.edu

    Xun Jia
  • Junghoon Lee

    Associate Professor
    junghoon@jhu.edu
    Lab: https://mica.jhu.edu/

    Junghoon Lee
  • Michael Roumeliotis

    Assistant Professor
    Director of Brachytherapy Physics
    mroumel1@jhu.edu

    Michael Roumeliotis