Research in the Allan Gottschalk Lab focuses on the mechanisms behind neuropathic pain, chronic pain related to nerve injury. We are investigating biophysical models of the impact of general anesthesia on the central nervous system; informational aspects of sensory perception and the representation of sensory input; nonlinear dynamics of respiratory pattern generation; and acute perioperative pain.

Research is the Yun Guan Lab explores the peripheral, spinal and supraspinal mechanisms of chronic pain. Our long-term goal is to develop better strategies and novel targets for treatment of pathological pain conditions. Our team’s multidisciplinary research uses electrophysiological, molecular biological, immunocytochemical and behavioral pharmacological approaches to study neurobiological mechanisms of pain and hyperalgesia that occur following tissue or nerve injury.