The mission the Translational Informatics Research and Innovation (TIRI) Lab is to understand and create advanced technology and digital device solutions that address challenges to the translation of biomedical data science-informed guidance into clinical use to improve the health of individuals, especially for people that are often underrepresented in research.

The GI Biomarkers Laboratory studies gastrointestinal cancer and pre-cancer biogenesis and biomarkers. The lab is led by Dr. Stephen Meltzer, who is known for his research in the molecular pathobiology of gastrointestinal malignancy and premalignancy. Research in the lab has led to several groundbreaking genomic, epigenomic and bioinformatic studies of esophageal and colonic neoplasms, shifting the gastrointestinal research paradaigm toward genome-wide approaches.