Research in Novel Therapeutic Forms
Immuno-radiotherapy
We explore the use of immunotherapy in combination with radiation therapy to enhance the immune response to cancer cells. We use imaging methods to monitor the normal tissue toxicity from immunotherapy combined with radiation therapy such as pneumonitis when treating lung cancer.
Nanotechnology
We utilize nanotechnology to develop new drug delivery systems and enhance the efficacy of radiation therapy such as magnetic hyperthermia therapy.
FLASH Radiotherapy
We focus on the development and optimization of FLASH radiation therapy, a type of radiation therapy that delivers high doses of radiation at an ultra-fast rate, in the order of milliseconds. We are also investigating the biological effects of FLASH radiation on normal and tumor tissues, and the potential benefits of FLASH radiation in reducing toxicity to healthy tissues while maintaining or improving tumor control.
Spatially Fractionated Radiation Therapy (SFRT)
Spatially Fractionated Radiation Therapy (SFRT) is a radiotherapy technique that delivers non-uniform dose distributions, characterized by alternating high and low doses across the tumor. We focus on understanding the underlying biological mechanisms and optimizing the impact of dosimetric and geometric parameters on the biological response and clinical outcomes. We also investigate the synergetic effects of SFRT in combination with other treatment modalities such as immunotherapy and FLASH radiation.
Core Faculty
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Kai Ding
Associate Professor
[email protected]
Lab: https://dinglab.jh.edu/ -
Heng Li
Associate Professor
Director of Proton Physics
Vice Chief of Physics/Clinical-NCR
[email protected] -
Devin Miles
Instructor
[email protected] -
Wil Ngwa
Associate Professor
[email protected] -
Mohammad Rezaee
Assistant Professor
[email protected] -
Khadija Sheikh
Assistant Professor
Associate Program Director of Medical Physics Residency
[email protected]