Physicians face fraught decisions on a daily basis. A Johns Hopkins training program prepares trainees to navigate the human side of medicine.

With Break the Cycle, violence intervention specialists help injured victims cope with deep trauma — ultimately interrupting the carnage that is claiming so many promising young lives in Baltimore.

Stigmatizing language in medical records follows patients, potentially exacerbating racial inequities, says Mary Catherine Beach, who is on a mission to raise awareness among physicians.

New ways to treat depression could begin in the gut, according to recent experiments in mice and humans led by Johns Hopkins Medicine researchers. 

A quick clinical test developed by researchers at Johns Hopkins Medicine and several other institutions could predict which people with neck pain are more likely to benefit from epidural steroid injections, which deliver drugs directly around the spinal nerves to stop nerve inflammation and reduce pain.

A new drug, a monoclonal antibody known as enoblituzumab, is safe in men with aggressive prostate cancer and may induce clinical activity against cancer throughout the body, according to a phase 2 study led by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. If confirmed in additional studies, enoblituzumab could become the first promising antibody-based immunotherapy agent against prostate cancer.

Newly diagnosed people with Crohn’s disease in the United States are more likely to experience drug and alcohol use compared with the general population, according to a recent study led by Johns Hopkins Medicine researchers. The study, which used data from Medicaid between 2010–2019, found that 16.3% of enrollees had some form of substance use at the time of Crohn’s diagnosis, with alcohol and opioids being the most commonly used substances.

Johns Hopkins Medicine researchers collaborated with NASA to send human heart “tissue-on-a-chip” specimens into space in March aboard SpaceX CRS-27, a resupply mission to the International Space Station. The project is designed to monitor the tissue for changes in heart muscle cells’ mitochondria  and ability to contract in low-gravity conditions.

“Although we have a highly successful kidney transplant program, we’ve been limited — like other medical institutions — by the shortage of available human donor organs. Hopefully, xenotransplantation will soon be able to join other strong efforts at Johns Hopkins to address this challenge, such as our nondirected [altruistic] and directed [designated recipient] living donor programs.”

With a $35 million gift from researcher, philanthropist and race car driver Theodore Giovanis, scientists at Johns Hopkins Medicine will study the biological roots of the most fatal aspect of cancer: how it metastasizes, or spreads, through the body.

Jennifer Nickoles, who has served as interim president of Johns Hopkins Bayview Medical Center since July 2022, was named president in April.

"The AMA has been devoting a lot of attention to the opioid epidemic, and some attention to incarcerated populations, but the issue of pregnant incarcerated people with opioid use disorder has not really crossed its radar. It was very gratifying for them to take an interest and recognize the critical issues that this population faces.”

Johns Hopkins’ Jeremy Greene, a noted historian of how medical technology influences our understandings of sickness and health, has been awarded a Guggenheim Fellowship — one of 171 scientists, writers, scholars and artists selected for the prestigious honor from a pool of nearly 2,500 applicants.

The number of Johns Hopkins Ph.D. students across the university’s Ph.D. programs who will now be represented by TRU-UE (Teachers and Researchers United—United Electrical, Radio and Machine Workers of America) in collective bargaining with the university.

Five researchers from the Johns Hopkins University School of Medicine were elected as 2022 fellows of the American Association for the Advancement of Science — one of the highest distinctions in the global science community, which recognizes both achievements in science and scientific integrity. They join more than 500 researchers inducted into the 2022 class of fellows.

This issue's note from the editor, plus letters from our readers.

The slope that ends in health inequities begins with our own unconscious bias.

Summer learning can be the first step in creating a more diverse health care workforce.

Matthews heads the new International African American Museum in Charleston.

As chief medical officer for USA Nordic, Chen is advocating for national safety standards.

Kalyani’s latest book highlights top athletes who’ve flourished because of their condition.

Migeon led field-defining research in X-inactivation.

Pakula left a far-reaching legacy at Johns Hopkins and beyond.

Partin led research and discovery in the field of urology.

The Johns Hopkins Sidney Kimmel Cancer Center celebrates 50 years of innovation in treatment and patient care.