Risk Distribution Estimation

For a given pathological stage (organ confined, extraprostatic extension, seminal vesicle Invasion, lymph node invasion), we estimated the distribution of the risk (probability of being in this pathological stage) for patients in the entire Johns Hopkins Hospital (JHH) cohort (N=5730).

Figure 4 -y coordinate is p , x coordinate is v                (0,1)=(0%,100%)) from the BJU Int. paper shows the risk quantile curve for each pathological stage and their 95% confidence interval (CI).

First , given two input values (pathological stage, and a value p in (0, 100%)), the software program below returns the estimated proportion of subjects in the JHH cohort with the probability (likelihood) of being in this pathological stage less than p , together with its 95% CI. For example, if we enter p as the probability of being organ confined for an individual patient determined from the left-side table, then the output will show the proportion of subjects in the JHH cohort with smaller probability of being organ confined compared to this patient — in other words the placement of the patient's risk of being organ confined relative to others in the JHU population.

Second , given two input values (pathological stage, and a value v  in (0, 100%)), the software program below returns the vth percentile of the probability of being in this pathological stage in the entire JHH cohort and its 95% CI. For example, if one selects  organ confined and a low v1=5% to get one output and then selects  organ confined and a high v2 =95% to get another output, the two outputs will provide the fifth to 95th percentiles of the probability of being organ confined in JHU population.