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Brady Urological Institute

Estimate Your Risk

Calculate how aggressive your cancer is and see the preferred therapies for your diagnosis.
 

  • Estimate Your Risk

  • Very Low Risk

  • Low Risk

  • Intermediate Risk

  • High Risk

  • Very High Risk

  • Metastatic

Calculate

PSA:
Gleason score:
Clinical stage/rectal exam:
Note: Abnormal 1 : Does not extend beyond prostate Abnormal 2 : With extension beyond the prostate Imaging:

Very Low-Risk Prostate Cancer

  • PSA <10
  • Gleason 3+3=6 and fewer than two cores
  • Clinical exam: Normal

Management Options

  • Active surveillance
  • Open radical prostatectomy
  • Robotic radical prostatectomy
  • Radiation therapy

Clinical Trials

If you'd like to participate in a clinical trial at Johns Hopkins, visit the Institute for Clinical and Translational Research .

Low-Risk Prostate Cancer

  • PSA 0-10
  • Gleason 3+3=6 and more than two cores
  • Clinical exam: Normal or half abnormality, one side only

Management Options

These men have a very low risk of dying from prostate cancer and generally do well with most forms of therapy. This is the most common form of prostate cancer.

  • Active surveillance
  • Open radical prostatectomy
  • Robotic radical prostatectomy
  • Radiation therapy

Clinical Trials

If you'd like to participate in a clinical trial at Johns Hopkins, visit the Institute for Clinical and Translational Research .

Intermediate-Risk Prostate Cancer

  • PSA 10-20
  • Gleason 3+4 or 4+3
  • Clinical exam: Abnormality that does not extend beyond the boundary of the prostate

Management Options

  • Open radical prostatectomy
  • Robotic radical prostatectomy
  • Radiation therapy

Clinical Trials

If you'd like to participate in a clinical trial at Johns Hopkins, visit the Institute for Clinical and Translational Research .

High-Risk Prostate Cancer

  • PSA >20
  • Gleason 4+4 or 4+5, more than five cores
  • Clinical exam: Abnormality that extends beyond the prostate with no fixation

Management Options

These men have a much higher risk of recurrence with surgery or radiation or surveillance, and often benefit from more aggressive combination approaches.
  • Open radical prostatectomy
  • Robotic radical prostatectomy
  • Radiation therapy and two to three years of hormonal suppression

Clinical Trials

If you'd like to participate in a clinical trial at Johns Hopkins, visit the Institute for Clinical and Translational Research .

Very High-Risk Prostate Cancer

 

  • Gleason 5+4 or 4+5
  • Gleason 4+4 or 4+5 and more than four cores
  • Clinical exam

Management Options

  • Open radical prostatectomy
  • Robotic radical prostatectomy
  • Radiation therapy

Clinical Trials

If you'd like to participate in a clinical trial at Johns Hopkins, visit the Institute for Clinical and Translational Research .

Metastatic

  • PSA
  • Gleason
  • Clinical exam

Management Options

  • Hormone therapy
  • Chemotherapy
  • Radium 223
  • Immunotherapy

Clinical Trials

If you'd like to participate in a clinical trial at Johns Hopkins, visit the Institute for Clinical and Translational Research .

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