Skip to Main Content

Masks Strongly Recommended but Not Required in Maryland

Respiratory viruses continue to circulate in Maryland, so masking remains strongly recommended when you visit Johns Hopkins Medicine clinical locations in Maryland. To protect your loved one, please do not visit if you are sick or have a COVID-19 positive test result. Get more resources on masking and COVID-19 precautions.

Brady Urological Institute

Estimate Your Risk

Calculate how aggressive your cancer is and see the preferred therapies for your diagnosis.
 

  • Estimate Your Risk

  • Very Low Risk

  • Low Risk

  • Intermediate Risk

  • High Risk

  • Very High Risk

  • Metastatic

Calculate

PSA:
Gleason score:
Clinical stage/rectal exam:
Note: Abnormal 1 : Does not extend beyond prostate Abnormal 2 : With extension beyond the prostate Imaging:

Very Low-Risk Prostate Cancer

  • PSA <10
  • Gleason 3+3=6 and fewer than two cores
  • Clinical exam: Normal

Management Options

  • Active surveillance
  • Open radical prostatectomy
  • Robotic radical prostatectomy
  • Radiation therapy

Clinical Trials

If you'd like to participate in a clinical trial at Johns Hopkins, visit the Institute for Clinical and Translational Research .

Low-Risk Prostate Cancer

  • PSA 0-10
  • Gleason 3+3=6 and more than two cores
  • Clinical exam: Normal or half abnormality, one side only

Management Options

These men have a very low risk of dying from prostate cancer and generally do well with most forms of therapy. This is the most common form of prostate cancer.

  • Active surveillance
  • Open radical prostatectomy
  • Robotic radical prostatectomy
  • Radiation therapy

Clinical Trials

If you'd like to participate in a clinical trial at Johns Hopkins, visit the Institute for Clinical and Translational Research .

Intermediate-Risk Prostate Cancer

  • PSA 10-20
  • Gleason 3+4 or 4+3
  • Clinical exam: Abnormality that does not extend beyond the boundary of the prostate

Management Options

  • Open radical prostatectomy
  • Robotic radical prostatectomy
  • Radiation therapy

Clinical Trials

If you'd like to participate in a clinical trial at Johns Hopkins, visit the Institute for Clinical and Translational Research .

High-Risk Prostate Cancer

  • PSA >20
  • Gleason 4+4 or 4+5, more than five cores
  • Clinical exam: Abnormality that extends beyond the prostate with no fixation

Management Options

These men have a much higher risk of recurrence with surgery or radiation or surveillance, and often benefit from more aggressive combination approaches.
  • Open radical prostatectomy
  • Robotic radical prostatectomy
  • Radiation therapy and two to three years of hormonal suppression

Clinical Trials

If you'd like to participate in a clinical trial at Johns Hopkins, visit the Institute for Clinical and Translational Research .

Very High-Risk Prostate Cancer

 

  • Gleason 5+4 or 4+5
  • Gleason 4+4 or 4+5 and more than four cores
  • Clinical exam

Management Options

  • Open radical prostatectomy
  • Robotic radical prostatectomy
  • Radiation therapy

Clinical Trials

If you'd like to participate in a clinical trial at Johns Hopkins, visit the Institute for Clinical and Translational Research .

Metastatic

  • PSA
  • Gleason
  • Clinical exam

Management Options

  • Hormone therapy
  • Chemotherapy
  • Radium 223
  • Immunotherapy

Clinical Trials

If you'd like to participate in a clinical trial at Johns Hopkins, visit the Institute for Clinical and Translational Research .

Resources