Peter Mogayzel, director of the Cystic Fibrosis Center, discusses his presentation on the changing landscape of cystic fibrosis care, given during the 2023 North American Cystic Fibrosis Conference. The advent of highly effective CFTR modulators has transformed how practitioners approach care because patients are not as sick and have fewer clinic visits and hospitalizations. During this talk, Mogayzel explores the future of cystic fibrosis care.