Recent publications:

2024
Li TA, Gonzalez-Gil A, Awol AK, Ackerman SJ, Orsburn BC, Schnaar RL (2024) Sialylated keratan sulfates on MUC5B are Siglec-8 ligands in the human esophagus. Glycobiology 34:cwae065. View Abstract
Zhang GL, Porter MJ, Awol AK, Orsburn BC, Canner SW, Gray JJ, O'Meally RN, Cole RN, Schnaar RL (2024) The Human Ganglioside Interactome in Live Cells Revealed Using Clickable Photoaffinity Ganglioside Probes. J Am Chem Soc 146:17801-17816. View Abstract
Baez BB, Bacaglio CR, Prendergast JM, Rozes-Salvador V, Sheikh KA, Bianchet M, Farah MH, Schnaar RL, Bisbal M, Lopez PHH (2024) Tumor necrosis factor alpha receptor 1A transduces the inhibitory effect on axon regeneration triggered by IgG anti-ganglioside GD1a antibodies. Biochim Biophys Acta Mol Basis Dis 1870:167315. View Abstract
2023
Blazetic S, Krajina V, Labak I, Viljetic B, Pavic V, Ivic V, Balog M, Schnaar RL, Heffer M (2023) Sialyltransferase Mutations Alter the Expression of Calcium-Binding Interneurons in Mice Neocortex, Hippocampus and Striatum. Int J Mol Sci 24:17218. View Abstract
Schnaar RL (2023) Gangliosides as Siglec ligands. Glycoconj J 40:159-167. View Abstract
Gonzalez-Gil A, Li TA, Kim J, Schnaar RL (2023) Human sialoglycan ligands for immune inhibitory Siglecs. Mol Aspects Med 90:101110. View Abstract
2022
Kim DW, Tu KJ, Wei A, Lau AJ, Gonzalez-Gil A, Cao T, Braunstein K, Ling JP, Troncoso JC, Wong PC, Blackshaw S, Schnaar RL, Li T (2022) Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes. Mol Neurodegener 17:83. View Abstract
Varki A, Cummings RD, Esko JD, Stanley P, Hart G, Aebi M, Darvill A, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger PH (2022) Essentials of Glycobiology Fourth Edition. View
Gonzalez-Gil A, Porell RN, Fernandes SM, Maenpaa E, August Li T, Li T, Wong PC, Aoki K, Tiemeyer M, Yu ZJ, Orsburn BC, Bumpus NN, Matthews RT, Schnaar RL (2022) Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer’s disease. J Biol Chem 298:101960. View Abstract
Vivinetto AL, Castanares C, Garcia-Keller C, Moyano AL, Falcon C, Palandri A, Rozes-Salvador V, Rojas JI, Patrucco L, Monferran C, Cancela L, Cristiano E, Schnaar RL, Lopez PHH (2022) Myelin-associated glycoprotein activation triggers glutamate uptake by oligodendrocytes in vitro and contributes to ameliorate glutamate-mediated toxicity in vivo. Biochim Biophys Acta Mol Basis Dis 1868:166324. View Abstract
2021
Gonzalez-Gil A, Li TA, Porell RN, Fernandes SM, Tarbox HE, Lee HS, Aoki K, Tiemeyer M, Kim J, Schnaar RL (2021) Isolation, identification and characterization of the human airway ligand for the eosinophil and mast cell immunoinhibitory receptor Siglec-8. J Allergy Clin Immunol 147:1442-1452. View Abstract
Lee HS, Gonzalez-Gil A, Drake V, Li TA, Schnaar RL, Kim J (2021) Induction of the endogenous sialoglycan ligand for eosinophil death receptor Siglec-8 in chronic rhinosinusitis with hyperplastic nasal polyposis. Glycobiology 31:1026-1036. View Abstract
Büll C, Nason R, Sun L, Van Coillie J, Madriz Sørensen D, Moons SJ, Yang Z, Arbitman S, Fernandes SM, Furukawa S, McBride R, Nycholat CM, Adema GJ, Paulson JC, Schnaar RL, Boltje TJ, Clausen H, Narimatsu Y (2021) Probing the binding specificities of human Siglecs by cell-based glycan arrays. Proc Natl Acad Sci USA 118:e2026102118. View Abstract
Porter MJ, Zhang GL, Schnaar RL (2021) Ganglioside extraction, purification and profiling. J Vis Exp 169:e62385. View Abstract
Gonzalez-Gil A, Schnaar RL (2021) Siglec ligands. Cells 10:1260. View Abstract
Mlinac-Jerkovic K, Ilic K, Zjalić M, Mandić D, Debeljak Ž, Balog M, Damjanović V, Maček Hrvat N, Habek N, Kalanj-Bognar S, Schnaar RL, Heffer M (2021) Who's in, who's out? Re-evaluation of lipid raft residents. J Neurochem 58:657-672. View Abstract
Ilic K, Lin X, Malci A, Stojanovic M, Puljko B, Rozman M, Vukelic Z, Heffer M, Montag D, Schnaar RL, Kalanj-Bognar S, Herrera-Molina R, Mlinac-Jerkovic K (2021) Plasma membrane calcium ATPase-neuroplastin complexes are selectively stabilized in GM1-containing lipid rafts. Int J Mol Sci 22:13590. View Abstract
Walker MT, Ferrie RP, Hoji A, Schroeder-Carter LM, Cohen JD, Schnaar RL, Cook-Mills JM (2021) β-Glucosylceramide from allergic mothers enhances offspring responsiveness to allergen. Front Allergy 2:647134. View Abstract
McKitrick TR, Ackerman ME, Anthony RM, Bennett CS, Demetriou M, Hudalla GA, Ribbeck K, Ruhl S, Woo CM, Yang L, Zost SJ, Schnaar RL, Doering TL (2021) The crossroads of glycoscience, infection, and immunology. Front Microbiol 12:731008. View Abstract
2020
Lim H, Lee J, You B, Oh JH, Mok HJ, Kim YS, Yoon BE, Kim BG, Back SK, Park JS, Kim KP, Schnaar RL, Lee SJ (2020) GT1b functions as a novel endogenous agonist of toll-like receptor 2 inducing neuropathic pain. EMBO J 39:e102214. View Abstract
Liu H, Zheng Y, Zhang Y, Li J, Fernandes SM, Zeng D, Li X, Schnaar RL, Jia Y (2020) Immunosuppressive Siglec-E ligands on mouse aorta are up-regulated by LPS via NF-κB pathway. Biomed Pharmacother 122:109760. View Abstract
2019
Nycholat CM, Duan S, Knuplez E, Worth C, Elich M, Yao A, O'Sullivan J, McBride R, Wei Y, Fernandes SM, Zhu Z, Schnaar RL, Bochner BS, Paulson JC (2019) A sulfonamide sialoside analogue for targeting Siglec-8 and -F on immune cells. J Am Chem Soc 141:14032-14037. View Abstract
Guimarães AJ, de Cerqueira MD, Zamith-Miranda D, Lopez PH, Rodrigues ML, Pontes B, Viana NB, DeLeon-Rodriguez CM, Rossi DCP, Casadevall A, Gomes AMO, Martinez LR, Schnaar RL, Nosanchuk JD, Nimrichter L (2019) Host membrane glycosphingolipids and lipid microdomains facilitate Histoplasma capsulatum internalization by macrophages. Cell Microbiol 2019:e12976. View Abstract
Schnaar RL (2019) The biology of gangliosides. Adv Carbohydr Chem Biochem 76:113-148. View Abstract
Zhang Y, Zheng Y, Li J, Nie L, Hu Y, Wang F, Liu H, Fernandes SM, Zhong Q, Li X, Schnaar RL, Jia Y (2019) Immunoregulatory Siglec ligands are abundant in human and mouse aorta and are up-regulated by high glucose. Life Sci 216:189-199. View Abstract
Wei Y, Chhiba KD, Zhang F, Ye X, Wang L, Zhang L, Robida PA, Moreno-Vinasco L, Schnaar RL, Roers A, Hartmann K, Lee CM, Demers D, Zheng T, Bochner BS, Zhu Z (2019). Mast cell-specific expression of human Siglec-8 in conditional knock-in mice. Int J Mol Sci 20:E19. View Abstract

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