Janet M. Siliciano, PhD
Highlights
Languages
- English
Gender
FemaleJohns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Janet M. Siliciano
Primary Academic Title
Professor of Medicine
Background
Dr. Janet Siliciano is a Professor of Medicine in the Infectious Diseases Division in the Department of Medicine at the Johns Hopkins School of Medicine. She studies HIV latency, CD4-positive T-Lymphocytes, HIV cure, highly active antiretroviral therapy, T-lymphocytes, virus replication, viremia, and the HIV viral reservoir in resting CD4 T cells.
Dr. Siliciano holds a bachelor’s degree from the University of New Hampshire and a PhD from the Johns Hopkins University School of Medicine. She completed postdoctoral fellowships at Harvard Medical School and the Johns Hopkins University School of Medicine before joining the faculty.
Lab Website
Janet Siliciano Lab
- Research in the Janet Siliciano lab focuses on HIV. Areas of study include CD4-positive T lymphocytes, virus latency and highly active antiretrovirals. We recently explored the challenges of detecting HIV persistence during potentially curative interventions and the multifactorial nature of HIV-1 latency.
Selected Publications
Christine M Durand; Gabriel Ghiaur; Janet D Siliciano; S Alireza Rabi; Evelyn E Eisele; Maria Salgado; Liang Shan; Jun F Lai; Hao Zhang; Joseph Margolick; et al. HIV-1 DNA is detected in bone marrow populations containing CD4+ T cells but is not found in purified CD34+ hematopoietic progenitor cells in most patients on antiretroviral therapy. The Journal of infectious diseases 2012;205(6):1014-8.
Steven A Yukl; Eli Boritz; Michael Busch; Christopher Bentsen; Tae-Wook Chun; Daniel Douek; Evelyn Eisele; Ashley Haase; Ya-Chi Ho; Gero Hutter; et al. Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient. PLoS pathogens 2013;9(5):e1003347.
Susanne Eriksson; Erin H Graf; Viktor Dahl; Matthew C Strain; Steven A Yukl; Elena S Lysenko; Ronald J Bosch; Jun Lai; Stanley Chioma; Fatemeh Emad; et al. Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies. PLoS pathogens 2013;9(2):e1003174.