Jeff Mumm, PhD
Highlights
Languages
- English
Gender
MaleJohns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Jeff Mumm
Professional Titles
- Helen Larson & Charles Glenn Grover Professor in Ophthalmology
Primary Academic Title
Associate Professor of Ophthalmology
Background
Jeff Mumm, Ph.D., is the Helen Larson & Charles Glenn Grover Professor in Ophthalmology and an Associate Professor of Ophthalmology at the Wilmer Eye Institute. He also holds Associate Professor positions in the McKusick-Nathans Institute of Genetic Medicine, Department of Neuroscience, and the Center for Nanomedicine at the Johns Hopkins University School of Medicine. His areas of research include retinal regeneration, retinal circuitry and drug discovery. In his lab, he utilizes zebrafish to study the formation of neural circuits in the retina, as well as the regenerative capabilities of retinal cells, with the goal of developing better drugs to treat retinal diseases.
Dr. Mumm received his B.S. in biology from the University of Iowa and his Ph.D. in neuroscience at Washington University in St. Louis, MO. He then completed a postdoctoral fellowship at Washington University, focusing on neural circuit formation in the retina. He previously served as the president and research director of Luminomics in St. Louis, MO, and as an assistant professor of cellular biology and anatomy at Georgia Regents University before joining the Wilmer faculty in 2014.
Centers and Institutes
Recent News Articles and Media Coverage
Scientists at Johns Hopkins Take a Closer Look at How Zebrafish Regenerate Eye Tissue - JHU Hub (Jul. 2017)
Additional Academic Titles
Associate Professor of Neuroscience
Contact for Research Inquiries
Smith Building
400 North Broadway
Baltimore, MD 21287
Phone: (410) 502-2210
jmumm3@jhmi.edu
Research Interests
Drug delivery, Retinal circuitry, Retinal regeneration
Lab Website
Mumm Lab - Lab Website
Research Summary
Our research is focused on investigating the development, function, and regeneration of disease-relevant neurons and neural circuits responsible for vision. Our long-term goal is to apply what we learn from a naturally regenerative species, the zebrafish, toward the development of novel therapies for restoring visual function to patients. We place an emphasis on unique perspectives zebrafish afford to biological studies, such as in vivo time-lapse imaging of cellular behaviors and cell-cell interactions, and high-throughput chemical and genetic screening. We have pioneered several technologies to support this work including multicolor imaging of neural circuit formation, a selective cell ablation methodology, and a quantitative high-throughput phenotypic screening platform. Together, these approaches are providing novel insights into how the degeneration and regeneration of discrete retinal cell types is controlled.
Additional Training
Washington University, St. Louis, Missouri, 2004, Neural Circuit Formation in the Retina