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Charles J. Lowenstein, MD
Cardiology
- Johns Hopkins School of Medicine Faculty
About Charles J. Lowenstein
Professional Titles
- Michel Mirowski, M.D. Professor of Cardiology
- Director, Division of Cardiology
Primary Academic Title
Professor of Medicine
Background
Charles Lowenstein, M.D., is a cardiologist in Baltimore, Maryland. He also serves as director of the Division of Cardiology and co-director of the Johns Hopkins Heart and Vascular Institute.
Dr. Lowenstein originally came to Johns Hopkins as a cardiology fellow in 1991 after completing his medical residency at Massachusetts General Hospital and a research fellowship at the Massachusetts Institute of Technology. In 1993, he joined the Johns Hopkins faculty and helped lead the Ciccarone Center for the Prevention of Heart Disease until he was recruited in 2009 to become the chief of cardiology and director of the Aab Cardiovascular Research Institute at the University of Rochester School of Medicine and Dentistry. In 2020 he was hired to lead the Division of Cardiology at Hopkins.
He has served on the NIH Atherosclerosis and Inflammation Cardiovascular Sciences study section, and is a member of the Sarnoff Cardiovascular Research Foundation, an organization that funds medical student research. Dr. Lowenstein’s research focuses on vascular biology, exploring molecular mechanisms of vascular inflammation and thrombosis.
Videos
Additional Academic Titles
Professor of Genetic Medicine
Research Interests
Vascular biology
Research Summary
Venous thromboembolism is a major cause of morbidity and mortality. Thrombosis can be caused by acquired or inherited factors, but the genetic contribution to thrombosis is not well defined. Genome wide association studies have recently uncovered new pathways that cause thrombotic disease in humans.
The Lowenstein Lab uses human genetics to discover and characterize novel genes that regulate thrombosis and hemostasis. We collaborate with genetic epidemiologists who perform GWAS to identify genetic variants linked to vascular inflammation or thrombosis. We then characterize genetic loci linked to vascular inflammation or thrombosis. These approaches have revealed new pathways in endothelial cells and platelets that contribute to thrombosis and may lead to novel therapies to prevent abnormal bleeding and thrombosis.
Current Projects:
- Genetic causes of venous thromboembolism
- Genetic causes of abnormal endothelial activation
- Epigenetic regulation of coagulation factor production
Research Areas: vascular inflammation, thrombosis, hemostasis
Honors
- Peter Dolphin Award, 1/1/05
- Sir William Osler Young Investigator Award, 1/1/03
- Young Investigators Conference on Atherosclerosis Award, 1/1/00
Memberships
- NIH Atherosclerosis and Inflammation Cardiovascular Sciences study section
- Sarnoff Cardiovascular Research Foundation
- InterUrban Clinical Club
- American Society for Clinical Investigation
Locations
- Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville
- 10755 Falls Road, Pavilion I STE 360, Lutherville, MD 21093
- phone: 443-997-0270
- fax: 410-367-2448
Expertise
Education
Johns Hopkins University School of Medicine
Fellowship, 1993Massachusetts General Hospital
Fellowship, Medicine, 1991Massachusetts General Hospital
Residency, Medicine, 1989Harvard Medical School
Medical Education, MD, 1986Board Certifications
Cardiovascular Disease
American Board of Internal Medicine, 2004Internal Medicine
American Board of Internal Medicine, 1989Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Humana
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- UnitedHealthcare
- Veteran Affairs Community Care Network (Optum-VACCN)
Ratings & Reviews
4.9 out of 5
63 ratings, 28 reviewsThe Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
- 5 out of 5 starsReviewed on 1/21/2025
He was thorough and professional
- 5 out of 5 starsReviewed on 1/7/2025
Professional respectful and concerned about helping the patient get the best care for their wellbeing.
- 5 out of 5 starsReviewed on 1/7/2025
Excellent in assessment, meeting organization and recommendations.
- 5 out of 5 starsReviewed on 1/7/2025
Dr. Lowenstein is great!
- 5 out of 5 starsReviewed on 1/7/2025
The doctor took time with me
- 4 out of 5 starsReviewed on 12/17/2024
Highly intelligent, razor focused, engaged.
- 5 out of 5 starsReviewed on 12/17/2024
Dr. Lowenstein is a very impressive professional. The best I have encountered.
- 5 out of 5 starsReviewed on 12/17/2024
Excellent provider- informed, listened and offered explanation.
- 5 out of 5 starsReviewed on 11/12/2024
Was very knowledgeable.
- 5 out of 5 starsReviewed on 11/12/2024
My physician was very thorough, ask if I had questions or concerns, and showed me the utmost respect.
- 5 out of 5 starsReviewed on 11/5/2024
He was very professional and personable. He had researched my medical history before my appointment; therefore was able to address my concerns and answer any questions that I had.
- 5 out of 5 starsReviewed on 10/30/2024
Very thorough and well prepared.
- 5 out of 5 starsReviewed on 10/8/2024
Dr. Lowenstein is an outstanding person and a great clinician. He stabilized my severe hypertension and I followed his clinical advice for reducing my cholesterol level. Hopkins has many great clinicians; for sure, Dr Lowenstein is one of them. I am very lucky to have known him In the past several years.
- 5 out of 5 starsReviewed on 9/10/2024
This was an appointment to establish care, and I was impressed by Dr Lowenstein's thorough preparation for the visit.
- 5 out of 5 starsReviewed on 8/27/2024
He was patient, addressed my concerns, extremely knowledgeable and caring.
- 5 out of 5 starsReviewed on 8/27/2024
Dr Lowenstein is the greatest. Very polite concerned and caring
- 5 out of 5 starsReviewed on 7/23/2024
Outstanding care by this excellent physician.
- 5 out of 5 starsReviewed on 7/23/2024
Always well prepared
- 5 out of 5 starsReviewed on 7/2/2024
He's amazing! Super responsive and great problem solver.
- 5 out of 5 starsReviewed on 6/18/2024
Optimal
- 5 out of 5 starsReviewed on 6/11/2024
Dr. Lowenstein is very experienced and knowledgeable. As a patient, this is critical, and it makes you feel confident that your issue is being managed by someone who understands your situation. He is also quick to respond with results about your tests and any other questions you might have.
- 5 out of 5 starsReviewed on 6/4/2024
The best!!!!
- 5 out of 5 starsReviewed on 5/28/2024
This was my first time seeing/meeting Dr. Lowenstein. I met with him because my previous cardiologist is no longer there. This visit was an annual follow up and no treatment was needed.
- 5 out of 5 starsReviewed on 4/23/2024
Very cordial doctor . Listened to me and asked a lot of questions. Answered all my Questions. I was very impressed.
- 5 out of 5 starsReviewed on 4/9/2024
Very professional and a good listener.
- 5 out of 5 starsReviewed on 4/2/2024
Dr. Lowenstein was meticulous and thorough reviewing previous records and answering all of my questions. He addressed my concerns and explained everything in lay persons term which made it easy to understand.
- 5 out of 5 starsReviewed on 3/19/2024
My cardiological doctor was very good with questions and answers and I am very glad that I have him for my heart care.
- 5 out of 5 starsReviewed on 3/5/2024
Dr. Lowenstein is a very caring doctor and is truly interested in what you have to say. The Best!