Larry William Chang, MD, MPH

Professional Titles

• Co-Director, Center for Community and Global Health in Infectious Diseases (CCGHE-ID)

Primary Academic Title

Professor of Medicine

Background

Centers and Institutes

• AIDS Research - Clinical Core, Center for
• Global Health, Center for

Recent News Articles and Media Coverage

• “Exploring the Role of Mobile Technology as a Health Care Helper,” The New York Times, May 13, 2012

Research Interests

HIV implementation science, Mobile Health

Lab Website

Larry Chang Lab

• Research in the Larry Chang Lab focuses on innovative, multidisciplinary and pragmatic approaches to impacting the HIV/AIDS pandemic. Our research investigates ways to improve HIV/AIDS care in low- and middle-income settings through strategies that include quantitative methods, qualitative methods, community-based trial designs, and behavioral science and economic evaluations. In addition, we research mobile technologies for health (mHealth) strategies for improving global public health and clinical care, including novel applications for intimate-partner violence intervention, dengue surveillance, and HIV care, surveillance and prevention.

Research Summary

Dr. Chang’s primary research focus is HIV implementation science, specifically how to best implement HIV/AIDS treatment and prevention interventions (e.g., antiretroviral therapy) in resource-constrained settings. He has conducted randomized, controlled trials, observational studies and systematic reviews in this field. 

A related research area is mHealth (mobile health technology) strategies for improving global health and clinical care. Dr. Chang’s research is multidisciplinary, using mixed methods (quantitative and qualitative), and integrating behavioral science and economic evaluations with patient-oriented outcomes research.

Selected Publications

• Burkey MD, Weiser SD, Fehmie D, Alamo-Talisuna S, Sunday P, Nannyunja J, Reynolds SJ, Chang LW. “Socioeconomic determinants of mortality in HIV: evidence from a clinical cohort in Uganda.” J Acquir Immune Defic Syndr. 2014 May 1;66(1):41-7. doi: 10.1097/QAI.0000000000000094.

• Ferrada MA, Chang L. “A man with skin lesions and ataxia: a case of disseminated varicella zoster.” Int J Infect Dis. 2015 Apr;33:55. doi: 10.1016/j.ijid.2014.10.021. Epub 2014 Nov 13/

• Linas BS, Latkin C, Genz A, Westergaard RP, Chang LW, Bollinger RC, Kirk GD. “Utilizing mHealth methods to identify patterns of high risk illicit drug use.” Drug Alcohol Depend. 2015 Jun 1;151:250-7. doi: 10.1016/j.drugalcdep.2015.03.031. Epub 2015 Apr 5.

• Linas BS, Latkin C, Westergaard RP, Chang LW, Bollinger RC, Genz A, Kirk GD. “Capturing illicit drug use where and when it happens: an ecological momentary assessment of the social, physical and activity environment of using versus craving illicit drugs.” Addiction. 2015 Feb;110(2):315-25. doi: 10.1111/add.12768. Epub 2014 Nov 20.

• Reynolds SJ, Sempa JB, Kiragga AN, Newell K, Nakigozi G, Galiwango R, Gray R, Quinn TC, Serwadda D, Chang L. “Is CD4 monitoring needed among ugandan clients achieving a virologic and immunologic response to treatment?” AIDS Patient Care STDS. 2014 Nov;28(11):575-8. doi: 10.1089/apc.2014.0086. Epub 2014 Oct 7.

Honors

• Johns Hopkins Department of Medicine Research Retreat Clinical Fellow Abstract Honorable Mention, 1/1/09
• Society of General Internal Medicine, Clinical Vignette Award Winner,, 1/1/04
• Centers for Disease Control and Prevention Hubert Fellow, 1/1/01
• The American Federation for Clinical Research Award, 1/1/99

Memberships

• Member, Infectious Diseases Society of America (IDSA)
• Member, International AIDS Society (IAS)