Nada Alachkar, MD

Professional Titles

• Medical Director, Incompatible Kidney Transplant Program

Primary Academic Title

Associate Professor of Medicine

Background

Centers and Institutes

Comprehensive Transplant Center

Videos

• Managing the Health of Kidney Transplant Recipients

• Medical Management Kidney Transplant

Research Interests

Biomarker in Kidney transplant, High Immunologic Risk Kidney Transplant, Highly sensitized patients: response to desensitization treatments and post transplant outcome, Incompatible Kidney Transplant, Late AMR: response to therapy and outcome, Outcome of deceased donor kidney transplant recipients with positive crossmatch, Recurrence of atypical HUS, Recurrence of focal segmental glomerulosclerosis post kidney transplantation, Recurrent Glomerular Diseases in the Transplanted Kidney, the role of Eculizumab

Lab Website

Nada Alachkar Lab

• Dr. Alachkar's research focuses on recurrent glomerular diseases post kidney transplantation, in particular, FSGS.

  Also, her research work focuses on the outcome of incompatible kidney transplant and the risk of AMR.

  Other focus of her research is biomarkers in the kidney transplant that associate with rejection and recurrent diseases.

Google Scholar

https://scholar.google.com/citations?user=qs6V3KEAAAAJ&hl=en

PubMed

https://www.ncbi.nlm.nih.gov/pubmed/?term=alachkar+n

Selected Publications

• Alachkar N, Bagnasco SM, Montgomery RA. “Eculizumab for the treatment of two recurrences of atypical hemolytic uremic syndrome in a kidney allograft.” Transpl Int. 2012 Aug;25(8):e93-5. doi: 10.1111/j.1432-2277.2012.01497.x. Epub 2012 May 17.

• Alachkar N, Gupta G, Montgomery RA. “Angiotensin antibodies and focal segmental glomerulosclerosis.” N Engl J Med. 2013 Mar 7;368(10):971-3. doi: 10.1056/NEJMc1207233.

• Alachkar N, Lonze BE, Zachary AA, Holechek MJ, Schillinger K, Cameron AM, Desai NM, Dagher NN, Segev DL, Montgomery RA, Singer AL. “Infusion of high-dose intravenous immunoglobulin fails to lower the strength of human leukocyte antigen antibodies in highly sensitized patients.” Transplantation. 2012 Jul 27;94(2):165-71. doi: 10.1097/TP.0b013e318253f7b6.

• Alachkar N. “Serum and urinary biomarkers in acute kidney transplant rejection.” Nephrol Ther. 2012 Feb;8(1):13-9. doi: 10.1016/j.nephro.2011.07.409. Epub 2011 Oct 21. Review.

• C John Sperati; Nada Alachkar; Ronald Rodriguez; Mark Haas; Michael J Choi; Incidental discovery of a renal cell carcinoma on native kidney biopsy. American journal of kidney diseases : the official journal of the National Kidney Foundation 2010;56(1):175-80. 2010

• Latt N, Alachkar N, Gurakar A. “Hepatitis C virus and its renal manifestations: a review and update.” Gastroenterol Hepatol (N Y). 2012 Jul;8(7):434-45.

• N Alachkar; R Ugarte; E Huang; K L Womer; R Montgomery; E Kraus; H Rabb; Stem cell factor, interleukin-16, and interleukin-2 receptor alpha are predictive biomarkers for delayed and slow graft function. Transplantation proceedings 2010;42(9):3399-405. 2010

• Nada Alachkar; Hamid Rabb; Bernard G Jaar; Urinary biomarkers in acute kidney transplant dysfunction. Nephron. Clinical practice 2011;118(2):c173-81; discussion c181. 2011 

• Post Transplant Day 2 Serum and Urine Inflammatory Biomarkers Predict Early Acute Rejection and Acute Tubular Necrosis on Biopsy and Delayed Graft function; Nada Alachkar, Richard Ugarte, Edmund Huang, Karl Womer, Robert Montgomery, Edward Kraus and Hamid Rabb. Transplant Nephrology and Transplant Surgery, Johns Hopkins University, Baltimore, MD. Poster presented at the ASN Renal Week in November 2008

• Sharif A, Alachkar N, Bagnasco S, Geetha D, Gupta G, Womer K, Arend L, Racusen L, Montgomery R, Kraus E. “Incidence and outcomes of BK virus allograft nephropathy among ABO- and HLA-incompatible kidney transplant recipients.” Clin J Am Soc Nephrol. 2012 Aug;7(8):1320-7. doi: 10.2215/CJN.00770112. Epub 2012 May 24.

• Sharif A, Alachkar N, Kraus E. “Incompatible kidney transplantation: a brief overview of the past, present and future.” QJM. 2012 Dec;105(12):1141-50. doi: 10.1093/qjmed/hcs154. Epub 2012 Aug 20. Review.

• Sharif A, Zachary AA, Hiller J, Segev D, Alachkar N, Kraus ES, Desai NM, Dagher NN, Singer AL, Montgomery RA. “Rescue kidney paired donation as emergency salvage for failed desensitization.” Transplantation. 2012 Apr 15;93(7):e27-9. doi: 10.1097/TP.0b013e318249b10e.

• Singer AL, Alachkar N, Montgomery RA, Zachary AA. “Reply to ‘Defining the benefits of desensitization therapy.’” Transplantation. 2013 Mar 27;95(6):e33. doi: 10.1097/TP.0b013e3182845ffb.

• Szabo Z, Alachkar N, Xia J, Mathews WB, Rabb H. “Molecular imaging of the kidneys.” Semin Nucl Med. 2011 Jan;41(1):20-8. doi: 10.1053/j.semnuclmed.2010.09.003.

Honors

Ranked first in class of final year of Medical School, Aleppo University

Memberships

• American Society of Nephrology
• American Society of Transplantation