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Javier Bolanos Meade

Javier Bolanos Meade, MD

Hematologic Malignancy

Accepting New Patients
5.0 of 5 stars35 ratings, 15 reviews

Highlights

Languages

  • Spanish
  • English

Gender

Male

Johns Hopkins Affiliations:

  • Johns Hopkins School of Medicine Faculty

About Javier Bolanos Meade

Primary Academic Title

Professor of Oncology

Background

As a member of the Johns Hopkins Kimmel Cancer Center, my group's research is focused on finding novel therapies for the treatment of both acute and chronic graft versus host disease (GVHD). To that end, we are developing new strategies for prophylaxis as well as therapies for this problem. We are exploring the use of drugs such as pentostatin in steroid refractory GVHD. This drug inhibits an enzyme, called ADA, that induces apoptosis (cell death) of lymphocytes, the effector cells in GVHD. Our results using this approach have been quite encouraging. Also, we are exploring other novel approaches such as extracorporeal photopheresis or high-dose cyclophosphamide. We are participating in the NIH Bone Marrow Transplant Clinical Trials Network consortium to find useful therapies for GVHD. We are also members of the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials on Chronic GVHD, and there we are trying to establish rational guidelines for supportive care, trial design, etc. We run an internationally unique GVHD multidisciplinary clinic with many GVHD experts including a nurse practitioner, research nurse and others from fields such as physical medicine and rehabilitation, gastroenterology, ophthalmology, dermatology, pulmonology and more.

Clinical Trial Keywords

GVHD

Research Interests

GVHD, stem cell transplantation

Selected Publications

  • Bolanos-Meade, J. Update on the management of acute graft-versus-host disease. Curr Opin Oncol. 2006 Mar;18(2):120-125.

    Bolanos-Meade, J.; Hartley, E.; Jones, R.J. Long-term follow-up of allogeneic marrow transplantation for acute myelogenous leukemia after treatment with busulfan and cyclophosphamide. Biol Blood Marrow Transplant. 2006 Mar;12(3):366-367.

    Bolanos-Meade, J.; Vogelsang, G.B. Mesenchymal stem cells and organ transplantation: current status and promising future. Transplantation. 2006 May 27;81(10):1388-1389.

    Couriel, D.; Carpenter, P.A.; Cutler, C.; Bolanos-Meade, J.; Treister, N.S.; Gea-Banacloche, J.; Shaughnessy, P.; Hymes, S.; Kim, S.; Wayne, A.S.; Chien, J.W.; Neumann, J.; Mitchell, S.; Syrjala, K.; Moravec, C.K.; Abramovitz, L.; Liebermann, J.; Berger, A.; Gerber, L.; Schubert, M.; Filipovich, A.H.; Weisdorf, D.; Schubert, M.M.; Shulman, H.; Schultz, K.; Mittelman, B.; Pavletic, S.; Vogelsang, G.B.; Martin, P.J.; Lee, S.J.; Flowers, M.E. Ancillary therapy and supportive care of chronic graft-versus-host disease: national institutes of health consensus development project on criteria for clinical trials in chronic Graft-versus-host disease: V. Ancillary Therapy and Supportive Care Working Group Report. Biol Blood Marrow Transplant. 2006 Apr;12(4):375-396.

    Bolanos-Meade, J.; Anders, V.; Wisell, J.; Farmer, E.R.; Vogelsang, G.B. Grover's Disease after Bone Marrow Transplantation. Biol Blood Marrow Transplant. 2007 Sep;13(9):1116-1117.

    Bolanos-Meade, J.; Garrett-Mayer, E.; Luznik, L.; Anders, V.; Webb, J.; Fuchs, E.J.; Huff, C.A.; Matsui, W.; Borrello, I.M.; Brodsky, R.; Kasamon, Y.L.; Swinnen, L.J.; Flinn, I.W.; Ambinder, R.F.; Jones, R.J.; Hess, A.D.; Vogelsang, G.B. Induction of autologous graft-versus-host disease: results of a randomized prospective clinical trial in patients with poor risk lymphoma. Biol Blood Marrow Transplant. 2007 Oct;13(10):1185-1191.

    Bolanos-Meade, J.; Vogelsang, G.B. Montelukast in chronic graft-versus-host disease: a breath of fresh air Transplantation. 2007 Mar 15;83(5):527-528.

    Jacobsohn, D.A.; Chen, A.R.; Zahurak, M.; Piantadosi, S.; Anders, V.; Bolanos-Meade, J.; Higman, M.; Margolis, J.; Kaup, M.; Vogelsang, G.B. Phase II study of pentostatin in patients with corticosteroid-refractory chronic graft-versus-host disease. J Clin Oncol. 2007 Sep 20;25(27):4255-4261.

    Loyo, M.; Quintanilla-Dieck Mde, L.; Stein, B.; Bolanos-Meade, J. Bilateral subdural hematoma after hematopoietic stem cell transplantation: a diagnosis often overlooked. Leuk Lymphoma. 2007 Apr;48(4):835-836.

    Bolanos-Meade, J.; Vogelsang, G.B. Chronic graft-versus-host disease. Curr Pharm Des. 2008;14(20):1974-1986.

    Brodsky, R.A.; Luznik, L.; Bolanos-Meade, J.; Leffell, M.S.; Jones, R.J.; Fuchs, E.J. Reduced intensity HLA-haploidentical BMT with post transplantation cyclophosphamide in nonmalignant hematologic diseases. Bone Marrow Transplant. 2008 Oct;42(8):523-527.

    Luznik, L.; O'Donnell, P.V.; Symons, H.J.; Chen, A.R.; Leffell, M.S.; Zahurak, M.; Gooley, T.A.; Piantadosi, S.; Kaup, M.; Ambinder, R.F.; Huff, C.A.; Matsui, W.; Bolanos-Meade, J.; Borrello, I.; Powell, J.D.; Harrington, E.; Warnock, S.; Flowers, M.; Brodsky, R.A.; Sandmaier, B.M.; Storb, R.F.; Jones, R.J.; Fuchs, E.J. HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide. Biol Blood Marrow Transplant. 2008 Jun;14(6):641-650.

    Alousi, A.M.; Weisdorf, D.J.; Logan, B.R.; Bolanos-Meade, J.; Carter, S.; Difronzo, N.; Pasquini, M.; Goldstein, S.C.; Ho, V.T.; Hayes-Lattin, B.; Wingard, J.R.; Horowitz, M.M.; Levine, J.E. Etanercept, mycophenolate, denileukin, or pentostatin plus corticosteroids for acute graft-versus-host disease: a randomized phase 2 trial from the Blood and Marrow Transplant Clinical Trials Network. Blood. 2009 Jul 16;114(3):511-517.

    Bolanos-Meade, J.; Brodsky, R.A. Blood and marrow transplantation for sickle cell disease: overcoming barriers to success. Curr Opin Oncol. 2009 Mar;21(2):158-161.

    Bolanos-Meade, J.; Luznik, L.; Muth, M.; Matsui, W.H.; Huff, C.A.; Smith, B.D.; Levy, M.Y.; Kasamon, Y.L.; Swinnen, L.J.; Powell, J.D.; Brodsky, R.A.; Ambinder, R.F.; Jones, R.J.; Fuchs, E.J. Salvage transplantation for allograft failure using fludarabine and alemtuzumab as conditioning regimen. Bone Marrow Transplant. 2009 Mar;43(6):477-480.

    Fuchs, E.J.; Luznik, L.; Bolanos-Meade, J.; Miller, C.B.; Brodsky, R.A.; Ambinder, R.F.; Jones, R.J. Successful pregnancy and childbirth after reduced-intensity conditioning and partially HLA-mismatched BMT. Bone Marrow Transplant. 2009 Jun;43(12):969-970.

    Kasamon, Y.L.; Luznik, L.; Leffell, M.S.; Kowalski, J.; Tsai, H.L.; Bolanos-Meade, J.; Morris, L.E.; Crilley, P.A.; O'Donnell, P.V.; Rossiter, N.; Huff, C.A.; Brodsky, R.A.; Matsui, W.H.; Swinnen, L.J.; Borrello, I.; Powell, J.D.; Ambinder, R.F.; Jones, R.J.; Fuchs, E.J. Nonmyeloablative HLA-Haploidentical BMT with High-Dose Posttransplantation Cyclophosphamide: Effect of HLA Disparity on Outcome. Biol Blood Marrow Transplant. 2009 Nov 16.

    Kasamon, Y.L.; Wahl, R.L.; Ziessman, H.A.; Blackford, A.L.; Goodman, S.N.; Fidyk, C.A.; Rogers, K.M.; Bolanos-Meade, J.; Borowitz, M.J.; Ambinder, R.F.; Jones, R.J.; Swinnen, L.J. Phase II study of risk-adapted therapy of newly diagnosed, aggressive non-Hodgkin lymphoma based on midtreatment FDG-PET scanning. Biol Blood Marrow Transplant. 2009 Feb;15(2):242-248.

    Bolanos-Meade, J.; Smith, B.D.; Gore, S.D.; McDevitt, M.A.; Luznik, L.; Fuchs, E.J.; Jones, R.J. 5-Azacytidine as Salvage Treatment in Relapsed Myeloid Tumors after Allogeneic Bone Marrow Transplantation. Biol Blood Marrow Transplant. 2010 Oct 15;In Press.

    Karp, J.E.; Blackford, A.; Smith, B.D.; Alino, K.; Seung, A.H.; Bolanos-Meade, J.; Greer, J.M.; Carraway, H.E.; Gore, S.D.; Jones, R.J.; Levis, M.J.; McDevitt, M.A.; Doyle, L.A.; Wright, J.J. Clinical activity of sequential flavopiridol, cytosine arabinoside, and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia. Leuk Res. 2010 Jul;34(7):877-882.

    Kasamon, Y.L.; Luznik, L.; Leffell, M.S.; Kowalski, J.; Tsai, H.L.; Bolanos-Meade, J.; Morris, L.E.; Crilley, P.A.; O'Donnell, P.V.; Rossiter, N.; Huff, C.A.; Brodsky, R.A.; Matsui, W.H.; Swinnen, L.J.; Borrello, I.; Powell, J.D.; Ambinder, R.F.; Jones, R.J.; Fuchs, E.J. Nonmyeloablative HLA-haploidentical bone marrow transplantation with high-dose posttransplantation cyclophosphamide: effect of HLA disparity on outcome. Biol Blood Marrow Transplant. 2010 Apr;16(4):482-489.

    Luznik, L.; Bolanos-Meade, J.; Zahurak, M.; Chen, A.R.; Smith, B.D.; Brodsky, R.; Huff, C.A.; Borrello, I.; Matsui, W.; Powell, J.D.; Kasamon, Y.; Goodman, S.N.; Hess, A.; Levitsky, H.I.; Ambinder, R.F.; Jones, R.J.; Fuchs, E.J. High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease. Blood. 2010 Apr 22;115(16):3224-3230.

    Bolanos-Meade, J., and Vogelsang, G.B. (2008). Chronic graft-versus-host disease. Curr Pharm Des 14, 1974-1986.

    Brodsky, R.A., Luznik, L., Bolanos-Meade, J., Leffell, M.S., Jones, R.J., and Fuchs, E.J. (2008). Reduced intensity HLA-haploidentical BMT with post transplantation cyclophosphamide in nonmalignant hematologic diseases. Bone Marrow Transplant 42, 523-527.

    Luznik, L., O''Donnell, P.V., Symons, H.J., Chen, A.R., Leffell, M.S., Zahurak, M., Gooley, T.A., Piantadosi, S., Kaup, M., Ambinder, R.F., Huff, C.A., Matsui, W., Bolanos-Meade, J., Borrello, I., Powell, J.D., Harrington, E., Warnock, S., Flowers, M., Brodsky, R.A., Sandmaier, B.M., Storb, R.F., Jones, R.J., and Fuchs, E.J. (2008). HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide. Biol Blood Marrow Transplant 14, 641-650.

    Bolanos-Meade, J., and G. B. Vogelsang. 2007. Montelukast in chronic graft-versus-host disease: a breath of fresh air? Transplantation 83:527-8.

    Bolanos-Meade, J., E. Garrett-Mayer, L. Luznik, V. Anders, J. Webb, E. J. Fuchs, C. A. Huff, W. Matsui, I. M. Borrello, R. Brodsky, Y. L. Kasamon, L. J. Swinnen, I. W. Flinn, R. F. Ambinder, R. J. Jones, A. D. Hess, and G. B. Vogelsang. 2007. Induction of autologous graft-versus-host disease: results of a randomized prospective clinical trial in patients with poor risk lymphoma. Biol Blood Marrow Transplant 13:1185-91.

    Bolanos-Meade, J., V. Anders, J. Wisell, E. R. Farmer, and G. B. Vogelsang. 2007. Grover''s Disease after Bone Marrow Transplantation. Biol Blood Marrow Transplant 13:1116-7.

    Jacobsohn, D. A., A. R. Chen, M. Zahurak, S. Piantadosi, V. Anders, J. Bolanos-Meade, M. Higman, J. Margolis, M. Kaup, and G. B. Vogelsang. 2007. Phase II study of pentostatin in patients with corticosteroid-refractory chronic graft-versus-host disease. J Clin Oncol 25:4255-61.

    Loyo, M., L. Quintanilla-Dieck Mde, B. Stein, and J. Bolanos-Meade. 2007. Bilateral subdural hematoma after hematopoietic stem cell transplantation: a diagnosis often overlooked. Leuk Lymphoma 48:835-6.

    Bolanos-Meade, J. & Vogelsang, G. B. (2006). Mesenchymal stem cells and organ transplantation: current status and promising future. Transplantation 81, 1388-9.

    Bolanos-Meade, J. (2006). Update on the management of acute graft-versus-host disease. Curr Opin Oncol 18, 120-5.

    Bolanos-Meade, J., Hartley, E. & Jones, R. J. (2006). Long-term follow-up of allogeneic marrow transplantation for acute myelogenous leukemia after treatment with busulfan and cyclophosphamide. Biol Blood Marrow Transplant 12, 366-7.

    Couriel, D., Carpenter, P. A., Cutler, C., Bolanos-Meade, J., Treister, N. S., Gea-Banacloche, J., Shaughnessy, P., Hymes, S., Kim, S., Wayne, A. S., Chien, J. W., Neumann, J., Mitchell, S., Syrjala, K., Moravec, C. K., Abramovitz, L., Liebermann, J., Berger, A., Gerber, L., Schubert, M., Filipovich, A. H., Weisdorf, D., Schubert, M. M., Shulman, H., Schultz, K., Mittelman, B., Pavletic, S., Vogelsang, G. B., Martin, P. J., Lee, S. J. & Flowers, M. E. (2006).

    Ancillary therapy and supportive care of chronic graft-versus-host disease: national institutes of health consensus development project on criteria for clinical trials in chronic Graft-versus-host disease: V. Ancillary Therapy and Supportive Care Working Group Report. Biol Blood Marrow Transplant 12, 375-96.



    Bolaos-Meade, J., Zhou, L., Hoke, A., Corse, A., Vogelsang, G.,Wagner, K. R. In press. Hydroxychloroquine causes a severe vacuolar myopathy in a patient with chronic graft-versus-host disease. Am J Hematol.

    Bolaos-Meade, J., Ioffe, O., Hey, J., Vogelsang, G. B., Akpek, G. In press. Lymphocytic pneumonitis as the manifestation of acute graft-versus-host disease of the lung. Am J Hematol.

    Bolaos-Meade, J., Jacobsohn, D. A., Margolis, J., Ogden, A., Wientjes, M. G., Byrd, J. C., Lucas, D. M., Anders, V., Phelps, M., Grever, M. R., Vogelsang, G. B. In press. Pentostatin in steroid refractory acute graft-versus-host disease. J Clin Oncol.

Locations

  1. Sidney Kimmel Comprehensive Cancer Center
    • 401 North Broadway Street, Weinberg BLDG, Baltimore, MD 21287

    Expertise

    Education

    Johns Hopkins University School of Medicine

    Fellowship, 2003

    University of Maryland Medical Center

    Fellowship, Hematology and Oncology, 2002

    Texas Tech University Health Sciences Center

    Residency, Internal Medicine, 1999

    Escuela de Medicina - Ignacio A Santos

    Medical Education, MD, 1995

    Insurance

    Johns Hopkins providers accept various commercial health insurance plans. However, they may not be included in all of an insurance company's plans or offerings. This may include Exchange, Medicaid, Medicare, and specific limited benefit plans. Exceptions to participation also exist based on your employer’s benefits package and the provider's location or specialty. Please contact your insurer directly to make sure your doctor is covered by your plan. For more details, please review our Insurance Information.
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    • Pennsylvania's Preferred Health Networks (PPHN)
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    Ratings & Reviews

    5 out of 5

    35 ratings, 15 reviews

    The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

    Overall Rating by Patient
    Average provider Overall Rating by Patient rating 5 out of 5 stars
    Provider Listened Carefully
    Average provider Provider Listened Carefully rating 5 out of 5 stars
    Provider Explained Things Clearly
    Average provider Provider Explained Things Clearly rating 4.9 out of 5 stars
    Provider Knew Medical History
    Average provider Provider Knew Medical History rating 4.9 out of 5 stars
    Provider Showed Respect
    Average provider Provider Showed Respect rating 5 out of 5 stars
    Provider Spent Enough Time
    Average provider Provider Spent Enough Time rating 5 out of 5 stars
    Search reviews
      5 out of 5 stars
      Reviewed on 2/20/2025

      The doctor was very courteous, even going as far as listening intently to my medical history and related comments.

      5 out of 5 stars
      Reviewed on 1/16/2025

      Excellent top shelf

      5 out of 5 stars
      Reviewed on 1/16/2025

      I was very impressed with Dr Meade. His demeanor gave me comfort. His knowledge and experience was evident. He seemed very humane and understood very well my position as a patient with this dreadful illness.

      5 out of 5 stars
      Reviewed on 1/10/2025

      Dr Meade is a very compassionate thorough doctor who I believe hears my concerns.

      5 out of 5 stars
      Reviewed on 12/19/2024

      Dr. Meade is very thorough, takes the time to answer all our questions, and shows real concern. Thank you!

      5 out of 5 stars
      Reviewed on 11/7/2024

      They were kind and helpful to me.

      5 out of 5 stars
      Reviewed on 11/1/2024

      Appreciate Dr.Meade for assisting me on my journey.

      5 out of 5 stars
      Reviewed on 10/25/2024

      Very thorough. Good listener, allows me to participate in care decisions

      5 out of 5 stars
      Reviewed on 8/29/2024

      Top Notch! Best Oncologist you could have!!!

      5 out of 5 stars
      Reviewed on 8/1/2024

      Felt secure because of his honesty. He explained the process in detail, even though there would be an unpleasant time.

      5 out of 5 stars
      Reviewed on 7/25/2024

      Dr Javier Meade was my bone marrow transplant doctor . I received my transplant for AML on [ ] 2022 . This was my 2 year recheck. I feel blessed that he was my doctor at Hopkins!

      5 out of 5 stars
      Reviewed on 6/13/2024

      Dr. Bolaos is very good and you can tell that he has enough experience in his field

      5 out of 5 stars
      Reviewed on 4/22/2024

      Knowledgeable. Personable

      5 out of 5 stars
      Reviewed on 4/19/2024

      Dr JAVIER BOLANOS MEADE is an excellent, well-informed physician that explains complicated treatment in an easy to understand manner

      5 out of 5 stars
      Reviewed on 3/28/2024

      He is the best in gvhd