Edward W Gabrielson, MD
Clinical and Laboratory Pathology
- Johns Hopkins School of Medicine Faculty
About Edward W Gabrielson
Professional Titles
- Attending Pathologist, Johns Hopkins Hospital
- Attending Pathologist, Johns Hopkins Bayview Medical Center
Primary Academic Title
Professor of Pathology
Background
Dr. Edward W. Gabrielson is a Professor of Pathology and Oncology at the Johns Hopkins University School of Medicine and Professor of Environmental Health Engineering at the Johns Hopkins Bloomberg School of Public Health. He specializes in molecular pathology, with particular emphasis on the pathology of breast, esophageal and lung cancers. Dr. Gabrielson is a member of the Johns Hopkins Kimmel Cancer Center.
He received his M.D. from Northwestern University, completed a residency in pathology at the University of Colorado School of Medicine, followed by a fellowship in pathology at the National Institutes of Health.
Dr. Gabrielson has authored or co-authored approximately 200 peer-reviewed publications.
Additional Academic Titles
Professor of Oncology
Research Interests
Biomarkers, Breast cancer, Esophageal cancer, Lung cancer
Research Summary
Dr. Gabrielson investigates the molecular biology of breast cancer and lung cancer, emphasizing aspects that have potential clinical significance. Current areas of emphasis include molecular classification of cancers, genetic instability in cancer, and functional changes in cancers related to cell-cell interactions and cellular metabolism.
Selected Publications
Daniel J, Coulter J, Woo JH, Wilsbach K, Gabrielson E. High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells. Proc Natl Acad Sci U S A; 108: 5384-9, 2011
Gniadek TJ, Li QK, Tully E, Chatterjee S, Nimmagadda S, Gabrielson E. Heterogeneous expression of PD-L1 in pulmonary squamous cell carcinoma and adenocarcinoma: implications for assessment by small biopsy. Mod Pathol. 2017;30:530-53
Jhaveri TZ, Woo J, Shang X, Park BH and Gabrielson E. AMP-activated kinase (AMPK) regulates activity of HER2 and EGFR in breast cancer. Oncotarget. 2015; 6(17):14754-14765
Lemmon, C. R., Woo, J. H., Tully, E., Wilsbach, K., and Gabrielson, E. Nuclear factor-kappaB (NF-kappaB) mediates a protective response in cancer cells treated with inhibitors of fatty acid synthase. J Biol Chem, 286: 31457-31465, 2011
Li QK, Singh A, Biswal S, Askin F, Gabrielson E. KEAP1 gene mutations and NRF2 activation are common in pulmonary papillary adenocarcinoma. J Hum Genet; 56: 230-4, 2011
Graduate Program Affiliations
Pathology
Cellular and Molecular Medicine
Memberships
- United States and Canadian Academy of Pathology
- International Association for the Study of Lung Cancer
- Lungevity Foundation
Locations
- Johns Hopkins Bayview Medical Center
- 4940 Eastern Avenue, Baltimore, MD 21224
- phone: 410-550-0100
- fax: 410-550-0101
- The Johns Hopkins Hospital
- 1800 Orleans Street, Baltimore, MD 21287
- phone: 410-955-5000
- fax: 410-955-5001
Expertise
Education
National Institutes of Health
Fellowship, Pathology, 1985University of Colorado Anschutz Medical School
Residency, Pathology, 1982Northwestern University Feinberg School of Medicine
Medical Education, MD, 1977Board Certifications
Anatomic Pathology
American Board of Pathology, 1983Clinical Pathology
American Board of Pathology, 1983Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Humana
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- UnitedHealthcare
- Veteran Affairs Community Care Network (Optum-VACCN)