
Chiadi U. Onyike, MD
Neuropsychiatry
Psychiatry
Geriatric Psychiatry
- Johns Hopkins School of Medicine Faculty
About Chiadi U. Onyike
Professional Titles
- Director, Frontotemporal Dementias Program
- Director, Young-Onset Dementias Program
Primary Academic Title
Associate Professor of Psychiatry and Behavioral Sciences
Background
Dr. Onyike is a specialist in neuropsychiatry. He focuses on the diagnosis and care of neurodegenerative diseases that develop in midlife or earlier. These include frontotemporal dementias, young-onset Alzheimer diseases, prion diseases, leukodystrophy and other atypical conditions that cause cognitive and behavioral impairments and dementia. He is also engaged in research focused on the epidemiology and treatment of frontotemporal dementias, Alzheimer disease, Lewy body disease, spinocerebellar ataxias, and other neurodegenerative disorders.
Dr. Onyike has advised national and international research agencies, and philanthropic organizations, including the NIH, FDA, MRC-UK, and others. He is chair-elect of the Medical Advisory Council of the Association for Frontotemporal Degeneration, and serves on the Scientific Advisory Boards of the FTD Disorders Registry, the Tau Consortium, and the International Society for Neurodegenerative Diseases. He serves on the Alzheimer’s Association Best Clinical Practices Guidelines Work Group, and has participated in NIA/NINDS Alzheimer’s Disease and Related Dementias workshop committees. He is a founding member of the International Society for Frontotemporal Dementias, and a member of the Executive Committee.
Centers and Institutes
Clinical Trial Keywords
Alzheimer's; frontotemporal dementia; clinical trial
Research Interests
epidemiology, measurement and management of neurodegenerative disorders (including frontotemporal dementias, young-onset Alzheimer disease, Lewy body disease and other parkinsonian dementias, cerebrovascular dementias, prion disease, leukodystrophies), neuropathology, neuropsychiatry, Phenomenology, treatment development and clinical trials for neurodegenerative disease
Selected Publications
Kamath V, Chaney GS, DeRight J, Onyike CU. A meta-analysis of neuropsychological, social cognitive, and olfactory functioning in the behavioral and language variants of frontotemporal dementia. Psychol Med. 2018 Dec 6;:1-12. doi: 10.1017/S0033291718003604. PubMed PMID: 30520407
Kansal K, Mareddy M, Sloane KL, Minc AA, Rabins PV, McGready JB, Onyike CU. Survival in Frontotemporal Dementia Phenotypes: A Meta-Analysis. Dement Geriatr Cogn Disord. 2016;41(1-2):109-22. doi: 10.1159/000443205. Epub 2016 Feb 9. Review. PubMed PMID: 26854827
Kansal K, Yang Z, Fishman AM, Sair HI, Ying SH, Jedynak BM, Prince JL, Onyike CU. Structural cerebellar correlates of cognitive and motor dysfunctions in cerebellar degeneration. Brain. 2017 Mar 1;140(3):707-720. doi: 10.1093/brain/aww327. PubMed PMID: 28043955; PubMed Central PMCID: PMC5837314
Morrow CB, Leoutsakos J-MS, Onyike CU. Functional disabilities and psychiatric symptoms in primary progressive aphasia. Am J Geriatr Psychiatry 2022, 30(3):372-382.. PubMed PMID: 28059789; PubMed Central PMCID: PMC5652315
Tsapkini K, Webster KT, Ficek BN, Desmond JE, Onyike CU, Rapp B, Frangakis CE, Hillis AE. Electrical brain stimulation in different variants of primary progressive aphasia: A randomized clinical trial. Alzheimers Dement (N Y). 2018;4:461-472. doi: 10.1016/j.trci.2018.08.002. eCollection 2018. PubMed PMID: 30258975; PubMed Central PMCID: PMC6153381
Honors
- Board of Directors, Alzheimers Association of Greater Maryland
- Medical and Scientific Advisory Board, Alzheimers Association of Greater Maryland
- World Federation of Neurology Research Group on Aphasia and Cognitive Disorders
- Medical Advisory Committee, Association for Frontotemporal Degeneration
- Finance Committee, International Society for Frontotemporal Dementias
- Peripheral and Central Nervous Systems Drugs Advisory Committee, US Food and Drug Administration
Memberships
- American Association for Geriatric Psychiatry
- American Neuropsychiatric Association
- American Psychiatric Association
- International Psychogeriatric Society
- International Society for Frontotemporal Dementias
- International Society to Advance Alzheimer Research and Treatment (ISTAART)
- Maryland Psychiatric Society
- Society for Behavioral and Cognitive Neurology
- Association of Nigerian Physicians in the Americas
Expertise
Education
Johns Hopkins University School of Medicine
Fellowship, 2002Johns Hopkins Bloomberg School of Public Health
Graduate School, MHS, 2002Johns Hopkins University School of Medicine
Residency, Psychiatry, 2000College of Medicine
Medical Education, MD, 1991Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Humana
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- UnitedHealthcare
- Veteran Affairs Community Care Network (Optum-VACCN)