Duvuru Geetha, MBBS

Professional Titles

• Associate Director, Johns Hopkins Vasculitis Center
• Co-Director, Johns Hopkins Glomerular Disease Clinic

Primary Academic Title

Professor of Clinical Medicine

Background

Centers and Institutes

Vasculitis Center

Clinical Trial Keywords

ANCA vasculitis; Membranous nephropathy

Clinical Trials Summary

Rituximab in ANCA associated vasculitis: RAVE

Membranous Nephropathy Trial of Rituximab (MENTOR): A Randomized Controlled Trial of Rituximab versus Cyclosporine in the Treatment of Idiopathic Membranous Nephropathy (IMN)

BREVAS vasculitis trial: A Phase 3, Multi-Center, Multinational, Randomized, Double-Blind, Study to Evaluate the Efficacy and Safety of Belimumab (HGS1006) in Combination with Azathioprine for the Maintenance of Remission in Wegener’s Granulomatosis and Microscopic Polyangiitis 

Avacopan for the treatment of ANCA associated vasculitis: ADVOCATE

Research Interests

ANCA associated vasculitis, Glomerular diseases, IgA vasculitis

Lab Website

Duvuru Geetha Lab

• Dr. Geetha's team focuses on renal diseases in patients with systemic vasculitis as well as BK virus nephropathy in patients who have undergone renal transplant. Our studies include clinical trials on the effectiveness of rituximab versus cyclosporine in treating idiopathic membranous nephropathy and a multinational study of belimumab with azathioprine for maintaining remission of granulomatosis with polyangiitis and microscopic polyangiitis. We also have conducted research on the treatment of ANCA vasculitis, particularly in kidney transplant patients.

Selected Publications

• 1. Christine Murakami; Pradeep Manoharan; Naima Carter-Monroe; Duvuru Geetha; Rituximab for remission induction in recurrent ANCA-associated glomerulonephritis postkidney transplant. Transplant international : official journal of the European Society for Organ Transplantation 2013;26(12):1225-31. 2013 
  2. A Srivastava; G K Rao; P E Segal; M Shah; D Geetha; Characteristics and outcome of crescentic glomerulonephritis in patients with both antineutrophil cytoplasmic antibody and anti-glomerular basement membrane antibody. Clinical rheumatology 2013;32(9):1317-22. 2013 
  3. E M Miloslavsky; U Specks; P A Merkel; P Seo; R Spiera; C A Langford; G S Hoffman; C G M Kallenberg; E W St Clair; N K Tchao; et al. Clinical outcomes of remission induction therapy for severe antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis and rheumatism 2013;65(9):2441-9. 2013 
  4. Colleen M Krajewski; Duvuru Geetha; Veronica Gomez-Lobo; Contraceptive options for women with a history of solid-organ transplantation. Transplantation 2013;95(10):1183-6. 2013 
  5. Tanu Duggal; Paul Segal; Megha Shah; Naima Carter-Monroe; Pradeep Manoharan; Duvuru Geetha; Antineutrophil cytoplasmic antibody vasculitis associated with influenza vaccination. American journal of nephrology 2013;38(2):174-8. 2013
  6. Carla L Ellis; Rebecca L Manno; John P Havill; Lorraine C Racusen; Duvuru Geetha; Validation of the new classification of pauci-immune glomerulonephritis in a United States cohort and its correlation with renal outcome. BMC nephrology 2013;14():210. 2013 
  7. Duvuru Geetha; Philip Seo; Advances in therapy for ANCA-associated vasculitis. Current rheumatology reports 2012;14(6):509-15. 2012 
  8. Gaurav Raman; Amar Srivastava; Duvuru Geetha; Outcome of renal transplantation in patients with both ANCA and anti-GBM antibodies. Transplantation 2012;94(5):e30-1. 2012 
  9. Adnan Sharif; Nada Alachkar; Serena Bagnasco; Duvuru Geetha; Gaurav Gupta; Karl Womer; Lois Arend; Lorraine Racusen; Robert Montgomery; Edward Kraus; Incidence and outcomes of BK virus allograft nephropathy among ABO- and HLA-incompatible kidney transplant recipients. Clinical journal of the American Society of Nephrology : CJASN 2012;7(8):1320-7. 2012 
  10. Duvuru Geetha; Philip Seo; Carla Ellis; Michael Kuperman; Stuart M Levine; Persistent or new onset microscopic hematuria in patients with small vessel vasculitis in remission: findings on renal biopsy. The Journal of rheumatology 2012;39(7):1413-7. 2012 
  11. Purva Sharma; Michael Kuperman; Lorraine Racusen; Duvuru Geetha; Fibrillary glomerulonephritis presenting as rapidly progressive glomerulonephritis. American journal of kidney diseases : the official journal of the National Kidney Foundation 2012;60(1):157-9. 2012 
  12. Duvuru Geetha; Stephen M Sozio; Mythili Ghanta; Michelle Josephson; Ron Shapiro; Darshana Dadhania; Sundaram Hariharan; Results of repeat renal transplantation after graft loss from BK virus nephropathy. Transplantation 2011;92(7):781-6. 2011 
  13. Duvuru Geetha; Shyam Parkhie; Girish N Nadkarni; Chun He; Tariq Shafi; Polyomavirus-associated nephropathy: a comparison of 2 different strategies for immunosuppression reduction. Medicine 2011;90(5):296-302. 2011 
  14. Duvuru Geetha; Alfonso Eirin; Karin True; Maria Valentina Irazabal; Ulrich Specks; Philip Seo; Patrick Nachman; Fernando C Fervenza; Renal transplantation in antineutrophil cytoplasmic antibody-associated vasculitis: a multicenter experience. Transplantation 2011;91(12):1370-5.  2011
  15. Duvuru Geetha; Mark Haas; Edward S Kraus; Hamid Rabb; Philip Seo; Renal transplant in Wegener's granulomatosis compared to microscopic polyangiitis. The Journal of rheumatology 2010;37(8):1705-8. 2010 
  16. John H Stone; Peter A Merkel; Robert Spiera; Philip Seo; Carol A Langford; Gary S Hoffman; Cees G M Kallenberg; E William St Clair; Anthony Turkiewicz; Nadia K Tchao; et al. Rituximab versus cyclophosphamide for ANCA-associated vasculitis. The New England journal of medicine 2010;363(3):221-32. 2010 
  17. D Geetha; P Seo; Renal transplantation in the ANCA-associated vasculitides. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(12):2657-62. 2007 
  18. D Geetha; P Seo; U Specks; F C Fervenza; Successful induction of remission with rituximab for relapse of ANCA-associated vasculitis post-kidney transplant: report of two cases. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(12):2821-5. 2007 
  19. Abraham Thomas; Lesia K Dropulic; M Hafizur Rahman; Duvuru Geetha; Ureteral stents: a novel risk factor for polyomavirus nephropathy. Transplantation 2007;84(3):433-6. 2007 
  20. Duvuru Geetha; Betty C Tong; Lorraine Racusen; Jay S Markowitz; William H Westra; Bladder carcinoma in a transplant recipient: evidence to implicate the BK human polyomavirus as a causal transforming agent. Transplantation 2002;73(12):1933-6. 2002 
  21. T H Goodship; J T Stoddart; V Martinek; D Geetha; A L Brown; M K Ward; D N Kerr; J P Owen; R Wilkinson; Long-term follow-up of patients presenting to adult nephrologists with chronic pyelonephritis and 'normal' renal function. QJM : monthly journal of the Association of Physicians 2000;93(12):799-803. 2000 
  22. D Geetha; J B Zachary; H M Baldado; J D Kronz; E S Kraus; Pure red cell aplasia caused by Parvovirus B19 infection in solid organ transplant recipients: a case report and review of literature. Clinical transplantation 2000;14(6):586-91. 2000 
  23. D Geetha; Omeprazole-induced acute interstitial nephritis. The American journal of gastroenterology 1999;94(11):3375-6. 1999 

Honors

• Member, Royal College of Physicians (U.K.)
• Fellow, American Society of Nephrology
• Consultant Vasculitis Foundation
• Inducted to Miller Coulson Academy of Clinical Excellence, 1/1/10

Memberships

• Member of American Society of Nephrology
• Member of American Society of Transplantation