Ahmet Hoke, MD, PhD

Professional Titles

• Director, Neuromuscular Division
• Director, Neuromuscular Pathology Laboratory
• Director, Merkin Peripheral Neuropathy and Nerve Regeneration Center

Primary Academic Title

Professor of Neurology

Background

Centers and Institutes

• Amyotrophic Lateral Sclerosis (ALS) Clinic
• Charcot-Marie Tooth Center
• Merkin Peripheral Neuropathy and Nerve Regeneration Center
• Peripheral Nerve Center

CV

https://hopkinsmedicine.org/-/media/neurology-neurosurgery/documents/cv/ahmet-hoke.pdf

Videos

• Meet Our Expert: Dr. Ahmet Hoke

Additional Academic Titles

Professor of Neuroscience

Research Interests

Peripheral Neuropathy, Traumatic nerve injuries and nerve regeneration

Lab Website

Merkin Peripheral Neuropathy and Nerve Regeneration Center - Lab Website

• The Merkin Center's goal is to advance peripheral neuropathy research, deepen our understanding of these conditions and their causes and develop viable therapies. The center will tackle pressing research questions in peripheral neuropathy, with a particular focus on areas that impede the development of better diagnostic and therapeutic strategies.

Research Summary

Dr. Hoke’s clinical practice focuses on peripheral neuropathies and nerve injuries. His clinical research focuses on idiopathic, toxic, and inflammatory neuropathies and he is the principal investigator of several natural history studies aimed at developing biomarkers and understanding genetic underpinnings of peripheral neuropathies. His basic research focuses on studies of biology of peripheral axons and Schwann cells and disorders affecting the peripheral nervous system, utilizing in vitro and in vivo models of peripheral neuropathies to study the mechanisms of axonal damage and identify therapeutic targets for drug development. In addition, he has a research interest on mechanisms of axonal regeneration, specifically on chronic nerve injury models that recapitulate the challenges of human nerve regeneration. 

Google Scholar

http://scholar.google.com/scholar?hl=en&q=Ahmet+Hoke&btnG=&as_sdt=1%2C21&as_sdtp=

PubMed

http://www.ncbi.nlm.nih.gov/pubmed/?term=hoke%2C+ahmet

Patents

• US10273451 (JHU Ref#: DM-4682): Immortalization of cells including neuronal cells; 2009 (April 30, 2019)
• US9707000 and CA2713214 (JHU Ref#: C-10297): Hydrogel-grafted degradable nerve guides (July 18, 2017)
• US9539009, JPN5988588 & JPN6039626 (JHU Ref#: C-10679): Biological tissue connection and repair devices and methods of using same (January 10, 2017)
• US9527817 (JHU Ref#: C11605): Compounds for treating peripheral; neuropathies and other neurodegenerative disorders (December 27, 2016)

Honors

• Alan J. Gebhart Prize for Excellence in Peripheral Nerve Research, Peripheral Nerve Society 2022

• Dr. Nejat Eczacibasi Medical Science Award, Dr. Nejat Eczacibasi Foundation, Istanbul, Turkey 2019

• Wolfe Neuropathy Research Award, American Neurological Association 2018

• Myung Memorial Lecture Award, Korean Neurological Association, 2017

• Discovery Innovation Award, The Johns Hopkins University School of Medicine, 11/11/17
• Derek Denny Brown Award, American Neurological Association, 1/1/05
• Clinician Scientist Award, Johns Hopkins University, 1/1/02
• Alberta Heritage Foundation for Medical Research Clinical Research Fellowship, Canada, 1/1/97
• Jay Slotkin Award for Excellence in Research, Johns Hopkins University, USA, 1/1/97

Graduate Program Affiliations

Neuroscience

Pathobiology

Memberships

• American Academy of Neurology
• American Neurological Association
• Peripheral Nerve Society
• Royal College of Physicians and Surgeons of Canada
• Society for Neuroscience