Fredrick Wigley, MD

Rheumatology

Accepting New Patients

5.0 of 5 stars186 ratings, 96 reviews

Highlights

Languages

English

In-Network Plans

View All Accepted Plans (14)

Gender

Male

Johns Hopkins Affiliations:

Johns Hopkins School of Medicine Faculty

About Fredrick Wigley

Professional Titles

Director, The Johns Hopkins Scleroderma Center
Martha McCrory Professor of Medicine

Primary Academic Title

Professor of Medicine

Background

Dr. Wigley received his M.D. degree from the University of Florida College of Medicine. He completed an internship and residency at Johns Hopkins where he also trained in a postdoctoral fellowship program. Dr. Wigley is a physician-scientist whose specialty is Raynaud’s phenomenon and scleroderma. He founded The Johns Hopkins Scleroderma Center with Robert A. Wise, M.D., of the Johns Hopkins Division of Pulmonary Medicine. Dr. Wigley has been honored with two American College of Rheumatology awards over the past couple years. He received the ACR Distinguished Clinician Scholar Award in 2009 and the ACR Masters Award in 2011.

Centers and Institutes

Scleroderma Center

Clinical Trial Keywords

Raynaud's phenomenon; Scleroderma

Lab Website

Fredrick Wigley Lab

The Frederick Wigley Lab is interested in the signs, symptoms and causes of scleroderma. We are testing new treatments for Raynaud√ïs phenomenon and scleroderma. Understanding the treatment approach to Raynaud's phenomenon and associated ischemia and how to prevent digital ulcers is important for clinicians caring for these patients. Work in our lab has provided guidance in the management of Raynaud's phenomenon and digital ischemic ulcers, including options for the practical pharmacologic and nonpharmacologic interventions.

Research Summary

Dr. Wigley’s research focuses on the events that cause scleroderma and on the signs and symptoms of scleroderma. He is testing new treatments for Raynaud’s phenomenon and scleroderma.

PubMed

http://www.ncbi.nlm.nih.gov/pubmed/?term=Wigley+FM%5BAuthor%5D

Selected Publications

1. Joseph CG, Darrah E, Shah AA, Skora AD, Casciola-Rosen LA, Wigley FM, Boin F, Fava A, Thoburn C, Kinde I, Jiao Y, Papadopoulos N, Kinzler KW, Vogelstein B, Rosen A. Association of the Autoimmune Disease Scleroderma with an Immunologic Response to Cancer. Science. 2013 Dec 5. [Epub ahead of print] PMID: 24310608
2. McMahan ZH, Wigley FM. Novel investigational agents for the treatment of scleroderma. Expert Opin Investig Drugs. 2013 Nov 22. [Epub ahead of print] PMID: 24261610
3. Gerber EE, Gallo EM, Fontana SC, Davis EC, Wigley FM, Huso DL, Dietz HC. Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma. Nature. 2013 Nov 7;503(7474):126-30. doi: 10.1038/nature12614. Epub 2013 Oct 9. PMID: 24107997
4. Tedford RJ, Mudd JO, Girgis RE, Mathai SC, Zaiman AL, Housten-Harris T, Boyce D, Kelemen BW, Bacher AC, Shah AA, Hummers LK, Wigley FM, Russell SD, Saggar R, Saggar R, Maughan WL, Hassoun PM, Kass DA. Right ventricular dysfunction in systemic sclerosis-associated pulmonary arterial hypertension. Circ Heart Fail. 2013 Sep 1;6(5):953-63. PMID: 23797369
5. Gelber AC, Manno RL, Shah AA, Woods A, Le EN, Boin F, Hummers LK, Wigley FM. Race and association with disease manifestations and mortality in scleroderma: a 20-year experience at the Johns Hopkins Scleroderma Center and review of the literature. Medicine (Baltimore). 2013 Jul;92(4):191-205. doi: 10.1097/MD.0b013e31829be125. Review. PMID: 23793108
6. Matucci-Cerinic M, Kahaleh B, Wigley FM. Review: evidence that systemic sclerosis is a vascular disease. Arthritis Rheum. 2013 Aug;65(8):1953-62. doi: 10.1002/art.37988. Review. No abstract available. PMID: 23666787
7. Cottrell TR, Wise RA, Wigley FM, Boin F. The degree of skin involvement identifies distinct lung disease outcomes and survival in systemic sclerosis. Ann Rheum Dis. 2013 Apr 20. [Epub ahead of print] PMID: 23606705
8. Shah AA, Wigley FM. My approach to the treatment of scleroderma. Mayo Clin Proc. 2013 Apr;88(4):377-93. doi: 10.1016/j.mayocp.2013.01.018. Review. PMID: 23541012
9. Hummers LK, Dugowson CE, Dechow FJ, Wise RA, Gregory J, Michalek J, Yenokyan G, McGready J, Wigley FM. A multi-centre, blinded, randomised, placebo-controlled, laboratory-based study of MQX-503, a novel topical gel formulation of nitroglycerine, in patients with Raynaud phenomenon. Ann Rheum Dis. 2013 Dec 1;72(12):1962-7. doi: 10.1136/annrheumdis-2012-201536. Epub 2012 Dec 25. PMID: 23268365
10. Shah AA, Chung SE, Wigley FM, Wise RA, Hummers LK. Changes in estimated right ventricular systolic pressure predict mortality and pulmonary hypertension in a cohort of scleroderma patients. Ann Rheum Dis. 2013 Jul;72(7):1136-40. doi: 10.1136/annrheumdis-2012-201861. Epub 2012 Aug 11. PMID: 22887850

Locations

Johns Hopkins Bayview Medical Center
- 5501 Hopkins Bayview Circle, Floor 1, Baltimore, MD 21224
- phone: 443-997-1552
- fax: 410-550-1033

Expertise

Education

Johns Hopkins University School of Medicine

Fellowship, Rheumatology, 1979

Johns Hopkins University School of Medicine

Residency, Medicine, 1975

University of Florida College of Medicine

Medical Education, Medicine, MD, 1972

Board Certifications

Rheumatology

American Board of Internal Medicine, 1980

Internal Medicine

American Board of Internal Medicine, 1975

Insurance

Johns Hopkins providers accept various commercial health insurance plans. However, they may not be included in all of an insurance company's plans or offerings. This may include Exchange, Medicaid, Medicare, and specific limited benefit plans. Exceptions to participation also exist based on your employer’s benefits package and the provider's location or specialty. Please contact your insurer directly to make sure your doctor is covered by your plan. For more details, please review our Insurance Information.

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Aetna
CareFirst
Cigna
First Health
Geisinger Health Plan
HealthSmart/Accel
Humana

Johns Hopkins Health Plans
MultiPlan
Pennsylvania's Preferred Health Networks (PPHN)
Point Comfort Underwriters
Private Healthcare Systems (PHCS)
UnitedHealthcare
Veteran Affairs Community Care Network (Optum-VACCN)

Ratings & Reviews

5 out of 5

186 ratings, 96 reviews

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

Overall Rating by Patient

Provider Listened Carefully

Provider Explained Things Clearly

Provider Knew Medical History

Provider Showed Respect

Provider Spent Enough Time

Search reviews

Search Reviews

5 out of 5 stars
Reviewed on 3/20/2025
Dr. Wigley called later that day with both test results and follow-up information. His level of care and compassion is of the highest quality.
5 out of 5 stars
Reviewed on 3/19/2025
Dr. Wigley is so friendly, thorough and caring. I trust him completely.
5 out of 5 stars
Reviewed on 3/19/2025
Dr. Wigley and the physician on fellowship were both incredibly thoughtful and thorough in how they dealt with us, explaining everything we needed to know, and providing guidance in a direct and emotionally supportive way. We couldn't be happier about being in their care.
5 out of 5 stars
Reviewed on 3/13/2025
Dr Wigley is patient, caring, and I respect his opinion. He cares about my entire well being.
5 out of 5 stars
Reviewed on 3/13/2025
Wish I could give Dr Wigley a rating higher than 10. He's an amazing compassionate empathetic knowledgeable physician. I trust him implicitly
5 out of 5 stars
Reviewed on 3/6/2025
Dr Wigley is the absolute best doctor.
5 out of 5 stars
Reviewed on 3/5/2025
Knowledgeable and experienced
5 out of 5 stars
Reviewed on 2/27/2025
Dr. Wigley is a phenominal physician. He's kind, professional, caring and always gives you the time necessary.
5 out of 5 stars
Reviewed on 2/19/2025
The best
5 out of 5 stars
Reviewed on 2/18/2025
I LOVE Dr. Wigley! He is intelligent, caring and supportive. He is my favorite doctor and I would highly recommend to all friends and family.
5 out of 5 stars
Reviewed on 2/18/2025
Dr. Wigley is the best!
5 out of 5 stars
Reviewed on 2/13/2025
Nicest provider ever. I am so thankful. He goes above and beyond. He made me feel so comfortable talking to him
5 out of 5 stars
Reviewed on 2/13/2025
My provider of 30 years has prove himself to be efficient, knowledgeable , caring, and always seeking my best interest.I respect and admire him as a doctor and individual.
5 out of 5 stars
Reviewed on 2/13/2025
Doctor Wigley is so amazing. He always spends so much time with me. Explains things thoroughly and most importantly I feel as if he truly cares.
5 out of 5 stars
Reviewed on 2/12/2025
Dr. Wigley is the best provider I could ever ask for. Without him watching over me I would not be in the excellent condition I am today!
5 out of 5 stars
Reviewed on 2/4/2025
Dr Wigley is the best there is.
5 out of 5 stars
Reviewed on 1/29/2025
Dr Wigley is the best doctor. He is very thorough and caring. He listens to you and always follows up immediately if you messsge him.
5 out of 5 stars
Reviewed on 1/28/2025
Dr. Wigley is the best! Very knowledgeable in most areas of health care.
5 out of 5 stars
Reviewed on 1/22/2025
Dr. Wigley is excellent. He is knowledgeable, caring, thorough, understanding and makes you feel valued and takes his time. He is the best in his field and looks at the "whole" patient when treating them. He has helped me the most over the years.
5 out of 5 stars
Reviewed on 1/21/2025
Dr. Wigley is the best scleroderma expect in the world AND he is a lovely, kind person. He is one in a million!
5 out of 5 stars
Reviewed on 1/21/2025
I"ve been under Dr Wigley care for the past 11 years and I get the best support as I continue to struggle with my disease
5 out of 5 stars
Reviewed on 1/16/2025
Have been a patient of Dr. Wigley for over 25 years. I will continue to be treated by him. In fact, I have my next OV with him scheduled.
5 out of 5 stars
Reviewed on 1/10/2025
Dr Wigley is an amazing doctor who explains the recommended care in layman's language. He is thorough and caring.
5 out of 5 stars
Reviewed on 1/2/2025
Dr Wigley is one of the best physicians I've ever met. He always brings studies for me to read is very informative and explains things in a matter in which I can understand my condition. He's at the cutting edge of research. And has amazing bedside manner.
5 out of 5 stars
Reviewed on 1/2/2025
I love Dr. Wigley. He has a great bedside manner and is always very punctual and explains things clearly.
5 out of 5 stars
Reviewed on 12/19/2024
Dr Wigley is the best doctor I have. He is knowledgeable and caring.
5 out of 5 stars
Reviewed on 12/19/2024
Great would not go any where else
5 out of 5 stars
Reviewed on 12/19/2024
Very professional and extremely knowlegeable and concerned about my health
5 out of 5 stars
Reviewed on 12/17/2024
Dr. Wigley is the best. His understanding of my autoimmune issues and excellent medical care throughout the years is very appreciated. I am grateful for him.
5 out of 5 stars
Reviewed on 12/17/2024
Dr Wigley is a first rate provider. He is friendly, takes his time, and explains everything well. I am grateful to have found him and appreciate every visit.
5 out of 5 stars
Reviewed on 12/5/2024
Excellent care and concern about my general health not only his area of expertise
5 out of 5 stars
Reviewed on 12/4/2024
Dr. Wigley treats my condition but is always concerned about my over all health
5 out of 5 stars
Reviewed on 12/3/2024
I trust Dr. Wigley and look forward to my appointments. When I have a question between visits he responds quickly.
5 out of 5 stars
Reviewed on 12/3/2024
Dr. Wigley is an exceptional physician. There is no one like him anywhere, and I travel several hours to see him.
5 out of 5 stars
Reviewed on 11/27/2024
Very knowledgeable. Thorough with explanations and exam. Concerned.Friendly, involved with your health condition.
5 out of 5 stars
Reviewed on 11/26/2024
Dr. Wigley is an amazing doctor. I fly from Phoenix, AZ just to see him. He is patient, thorough and explains things in a manner I can clearly understand.
5 out of 5 stars
Reviewed on 11/26/2024
Dr. Wigley is an extraordinary, one of a kind caregiver.
5 out of 5 stars
Reviewed on 11/26/2024
Dr. Wigley is fantastic- warm, respectful, knowledgeable and concerned for my health.
5 out of 5 stars
Reviewed on 11/21/2024
Dr. Wigley always includes me in decision-making
5 out of 5 stars
Reviewed on 11/21/2024
Dr. Wigley is the most wonderful doctor a patient could want, I travel from Cincinnati, OH each year for my visit
5 out of 5 stars
Reviewed on 11/6/2024
Dr Wigley always goes above and beyond.
5 out of 5 stars
Reviewed on 11/5/2024
Always goes above and beyond with my care including medication and test result follow ups. Is the best Dr I have ever had.
5 out of 5 stars
Reviewed on 11/5/2024
Dr Wigley I amazing!!!!!
5 out of 5 stars
Reviewed on 10/31/2024
Dr. Wigley is an amazing physician and I am so grateful for his care, concern, detail, clear communication, and professionalism! He is the Best Doctor I have ever had.
4 out of 5 stars
Reviewed on 10/31/2024
My provider was very prompt in assessing my recent visit with a portal message.
5 out of 5 stars
Reviewed on 10/29/2024
Dr. Wigley was prepared, listened, have a thorough examination and explanation of concerns going forward, along with ordering blood work to follow my progress.
5 out of 5 stars
Reviewed on 10/24/2024
I am always amazed at the wonderful care and the time given to my concerns every time I visit. The care is top notch.
5 out of 5 stars
Reviewed on 10/23/2024
Dr. Wigley is terrific. He's a great listener and takes the time to answer every question. He often follows up with a question to make sure you understand his answer. I am very happy with his care and concern for me.
5 out of 5 stars
Reviewed on 9/26/2024
Dr. Wigley is the most knowledgeable and caring physician I've ever met! I know a lot of doctors because my husband is also a physician.
5 out of 5 stars
Reviewed on 9/25/2024
Dr. Wigley is simply the best. He is an incredible listener, cares deeply for his patients, and spends quality time with you to make sure everything is covered. My favorite doctor I have ever seen and I have seen alot!
5 out of 5 stars
Reviewed on 9/24/2024
Dr. Wigley has been treating me since 1994 . He is one in a million and I feel blessed to be under his care.
5 out of 5 stars
Reviewed on 9/24/2024
Dr. Wigley is absolutely the greatest doctor ever!!!!!
5 out of 5 stars
Reviewed on 9/19/2024
Dr Wigley is an excellent provider.
5 out of 5 stars
Reviewed on 9/19/2024
Dr. Wigley is very attentive and informative. He explains and reviews all the test results and what the implications are.
5 out of 5 stars
Reviewed on 9/19/2024
Dr. Wigley has always been the only doctor l rely on for his expertise and skill. Without his invaluable service l would be a very sick woman.
5 out of 5 stars
Reviewed on 9/16/2024
Dr Wigley is beyond expert, knowledgeable, clinically astute and compassionate. I am grateful to have him.
5 out of 5 stars
Reviewed on 9/16/2024
Dr Wigley is someone that cares about you and moves mountains for you to get the right care
5 out of 5 stars
Reviewed on 9/11/2024
Dr Wigley is always prepared and con cd warned about my health issues
5 out of 5 stars
Reviewed on 9/10/2024
Dr. Wigley is the first provider to do such a thorough exam, listen intently to my specific needs, and follow up with other physicians to get the best care possible for me.
5 out of 5 stars
Reviewed on 9/5/2024
Dr. Wigley is 1 in a million. I have never before experienced a full understanding of any condition I have had prior to his visit. He is extremely thorough and thoughtful in both the examination and the follow-up. I feel very lucky to have the opportunity to have him as my physician.
5 out of 5 stars
Reviewed on 9/5/2024
Dr Wigley is a compassionate and amazing doctor. I am fortunate to have him as my doctor.
5 out of 5 stars
Reviewed on 9/5/2024
Dr. Wigley is very knowledgeable and caring.
5 out of 5 stars
Reviewed on 9/4/2024
I have total trust in Dr Wigley and his team
5 out of 5 stars
Reviewed on 9/4/2024
I've been under Dr Wigley care for over 11 years. His care, experience, and knowledge is what keeps me stable while dealing with Scleroderma issues
5 out of 5 stars
Reviewed on 8/28/2024
You're asking me about Dr Wigley?! He is THE VERY BEST
5 out of 5 stars
Reviewed on 8/28/2024
My provider was very professional, knowledgeable and caring concerning my illness. Put my mind at ease.
5 out of 5 stars
Reviewed on 8/22/2024
Don't let Dr Wigley retire.
5 out of 5 stars
Reviewed on 8/21/2024
Dr Wigley Is the most thorough, thoughtful doctor I've ever seen. He was patient and kind. He explained things in a way that I understood and he's been easy to reach since my appointment. I'm so thankful he exists!
5 out of 5 stars
Reviewed on 8/20/2024
Dr. Wigley has been taking care of me for 9 years.He supports my total health needs and not just those related to scleraderma.
5 out of 5 stars
Reviewed on 8/15/2024
Very professional, through and friendly
5 out of 5 stars
Reviewed on 8/14/2024
Very helpful, concerned, informed about my condition. Physical exam was thorough. Friendly, knowledgeable.
5 out of 5 stars
Reviewed on 8/13/2024
I am very blessed to have Dr. Wigley as my doctor. He is beyond caring, knowledgeable, and the most dedicated doctor that I've ever had. JH Is a better hospital for having Dr. Wigley as an employee!!
5 out of 5 stars
Reviewed on 8/13/2024
He is top notch
5 out of 5 stars
Reviewed on 8/8/2024
He's caring and responsive
5 out of 5 stars
Reviewed on 8/7/2024
Dr. Wigley excels in every aspect of care.
5 out of 5 stars
Reviewed on 7/30/2024
Dr. Wigley is the best. So knowledgeable and so compassionate.
5 out of 5 stars
Reviewed on 6/27/2024
He is very thorough and explains everything very well. He also explains his recommendations for future course of action. I especially like that he comments on my health holistically and seems to really care for my well being. He is an excellent doctor and a trusted source for my health care concerns and questions.
5 out of 5 stars
Reviewed on 6/18/2024
Dr. Wigley is the best and a hero
5 out of 5 stars
Reviewed on 6/18/2024
He is the best
5 out of 5 stars
Reviewed on 6/12/2024
Dr WIGLEY is the best. I travel from Florida for his expertise, knowledge, loving demeanor, dedication and his help. He looks at the whole picture and explains everything now and going forward. He is a most supportive and caring human. I only wish I could see him more often.
5 out of 5 stars
Reviewed on 6/11/2024
Dr Wigley always treats me with respect and as a pharmacist, he really listens to my suggestions during appointment.
5 out of 5 stars
Reviewed on 5/30/2024
Dr. Wigley is the best scleroderma dr. He treats his patients with so much compassion.
5 out of 5 stars
Reviewed on 5/30/2024
He is not only a great physician but also a nice human being
5 out of 5 stars
Reviewed on 5/28/2024
I am so thankful to be able to be seen by Dr Wigley. He is so kind and knowledgeable about my condition. He is a wonderful provider, he truly cares.
5 out of 5 stars
Reviewed on 5/28/2024
Dr. Wigley is the most caring provider of all time,
5 out of 5 stars
Reviewed on 5/23/2024
Great
5 out of 5 stars
Reviewed on 5/23/2024
Dr. Wigley is fantastic; he provides comprehensive, patient-focused care.
5 out of 5 stars
Reviewed on 5/14/2024
Dr. Wigley is without a doubt the best medical professional I have had. He is thorough, explains everything an makes me feel like a valued patient.
5 out of 5 stars
Reviewed on 5/9/2024
Dr. [Doctor's Name] is truly outstanding in the field of rheumatology and scleroderma. His expertise is matched only by his genuine care for his patients. His bedside manner is warm and comforting, making every visit a positive experience. I highly recommend him to anyone seeking compassionate and expert care.
5 out of 5 stars
Reviewed on 5/9/2024
Dr Wigley is the best ever!! He always listen, do the most careful check up and always gives a solution
5 out of 5 stars
Reviewed on 5/8/2024
Dr. Wigley, by far, did the most thorough exam of any provider since my diagnosis.
5 out of 5 stars
Reviewed on 5/8/2024
The very, very best.
5 out of 5 stars
Reviewed on 5/7/2024
He is calm but he considers the changes seriously
5 out of 5 stars
Reviewed on 4/30/2024
Dr. Wigley is the best physician I have ever encountered.
5 out of 5 stars
Reviewed on 4/25/2024
Dr Wigley is the best doctor I have ever seen. I am 68 years old.
5 out of 5 stars
Reviewed on 4/24/2024
Dr. Wigley is the most knowledgeable and caring doctor I have. He always takes the time to explain and figure out what is going on with my health. I trust him.