Nauder Faraday, MD, MPH

Professional Titles

• Senior Associate Dean for Appointments and Promotions
• Director, Perioperative Genomic and Translational Research, Department of Anesthesiology and Critical Care Medicine
• Director, Perioperative Hemostasis and Thrombosis Research Laboratory, Department of Anesthesiology and Critical Care Medicine
• Co-Director, Cardiac Surgical Intensive Care

Primary Academic Title

Professor of Anesthesiology and Critical Care Medicine

Background

CV

http://www.hopkinsmedicine.org/anesthesiology/faculty/cv/faraday.pdf

Additional Academic Titles

Professor of Surgery, Professor of Medicine

Research Interests

Genetic determinants of complications after surgery

Lab Website

Nauder Faraday Lab - Lab Website

Research Summary

Dr. Faraday’s research focuses on perioperative genetic and molecular medicine. His goal is to identify molecular determinants (genetic and protein) of outcome in surgical patients and to use these molecules to personalize care (by stratifying risk and developing novel therapeutics, for example) in the perioperative period.

His specific focus is on thrombotic, bleeding and infectious complications of surgery, which can result in serious complications after surgery.

Additionally, he and his team are working on research to help them construct predictive tools that will allow targeted use of novel antimicrobial and antithrombotic strategies, which maximize benefit and minimize risk to individual patients.

Selected Publications

• 1. Faraday N, Jaques K, Saleem S, Fu J, Wang B, Zhang J, Morrell C, Dore S. “Cathepsin G-dependent modulation of platelet thrombus formation in vivo by blood neutrophils.” PLoS One. 2013;8(8):e71447. doi: 10.1371/journal.pone.0071447.
  2. Kim Y, Suktitipat B, Yanek LR, Faraday N, Wilson AF, Becker DM, Becker LC, Mathias RA. “Targeted deep resequencing identifies coding variants in the PEAR1 gene that play a role in platelet aggregation.” PLoS One. 2013 May 21;8(5):e64179. doi: 10.1371/journal.pone.0064179.
  3. Lewis JP, Ryan K, O'Connell JR, Horenstein RB, Damcott CM, Gibson Q, Pollin TI, Mitchell BD, Beitelshees AL, Pakzy R, Tanner K, Parsa A, Tantry US, Bliden KP, Post WS, Faraday N, Herzog W, Gong Y, Pepine CJ, Johnson JA, Gurbel PA, Shuldiner AR. “Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes”. Circ Cardiovasc Genet. 2013 Apr;6(2):184-92. doi: 10.1161/CIRCGENETICS.111.964627. Epub 2013 Feb 7
  4. Faraday N, Rock P, Lin EE, Perl TM, Carroll K, Stierer T, Robarts P, McFillin A, Ross T, Shah AS, Riley LH, Tamargo RJ, Black JH, Blasco-Colmenares E, Guallar E. “Past history of skin infection and risk of surgical site infection after elective surgery.” Ann Surg. 2013 Jan;257(1):150-4. doi: 10.1097/SLA.0b013e3182588abf.
  5. Faraday N, Yanek LR, Yang XP, Mathias R, Herrera-Galeano JE, Suktitipat B, Qayyum R, Johnson AD, Chen M-H, Tofler GH, Ruczinski I, Friedman AD, Gylfason A, Thorsteinsdottir U, Bray PF, O’Donnell CJ, Becker DM, Becker LC. “Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression.” Blood. 2011 Sep 22;118(12):3367-75. doi: 10.1182/blood-2010-11-320788. Epub 2011 Jul 26.

Honors

• Who's Who in Medicine and Healthcare, Maurquis, 1/1/11
• Nominee, Johns Hopkins Leadership Development Program, 1/1/05
• Upjohn Achievement Award for Clinical Excellence, 1/1/88

Memberships

• Alpha Omega Alpha Honor Society
• American Medical Association
• American Society of Anesthesiologists
• International Anesthesia Research Society
• Society of Cardiovascular Anesthesiologists
• Society of Critical Care Medicine

Professional Activities

• American Journal of Cardiology, Ad hoc reviewer
• American Journal of Physiology, Ad hoc reviewer
• Anesthesia and Analgesia, Ad hoc reviewer
• Anesthesiology, Ad hoc reviewer
• Blood, Ad hoc reviewer
• British Journal of Clinical Pharmacology, Ad hoc reviewer
• Circulation, Ad hoc reviewer
• Diabetes/Metabolism Research Reviews, Ad hoc reviewer
• European Journal of Clinical Investigation, Ad hoc reviewer
• JAMA, Ad hoc reviewer
• Journal of Cellular and Molecular Medicine, Ad hoc reviewer
• PLOS ONE, Ad hoc reviewer
• Stroke, Ad hoc reviewer
• Thrombosis and Haemostasis, Ad hoc reviewer
• Thrombosis Research, Ad hoc reviewer