
Dan Hanley Jr., MD
Neurology
- Johns Hopkins School of Medicine Faculty
About Dan Hanley Jr.
Professional Titles
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Division Director, BIOS Clinical Trials Coordinating Center
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Deputy Director for Support and Innovation in Multicenter Trials at the Johns Hopkins Institute for Clinical and Translational Research
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Jeffrey and Harriet Legum Professor of Acute Care Neurology
Primary Academic Title
Professor of Neurology
Background
A leading expert on brain injury, Dr. Daniel F. Hanley has been a professor of neurology, neurosurgery, and anesthesiology/critical care medicine at the Johns Hopkins University School of Medicine since 1996 and was named the Jeffrey and Harriet Legum Chair of Acute Care Neurology. Dr. Hanley founded and directed the Johns Hopkins Neurocritical Care Unit, one of the first critical care units dedicated solely to neurosurgical and neurological patients. Subsequently, in 1999, he founded and continues to direct the BIOS Clinical Trials Coordinating Center (BIOS CTCC), formerly known as the Division of Brain Injury Outcomes.
Under Dr. Hanley’s leadership, BIOS CTCC, an academic contract research organization based at Johns Hopkins, has organized and completed more than 20 large clinical trials. He has been awarded over 70 clinical and basic research grants, predominantly from the National Institutes of Health and the FDA Orphan Products Grants Program.
Dr. Hanley’s 40-year career in medicine has focused on clinical trial design, the organization and interpretation of drug and device trials, the development of strategic research plans, and FDA regulatory compliance. He has led international, NIH-sponsored trials including the MISTIE III and CLEAR III trials investigating minimally invasive neurosurgical techniques to treat hemorrhagic stroke. As principal investigator for the National Center for Advancing Translational Sciences (NCATS) Johns Hopkins Trial Innovation Center, Dr. Hanley leads collaborative efforts to advance education and therapeutics through innovative CTSA clinical trials.
Currently, Dr. Hanley is the PI or multi-PI for several ongoing trials. These include a multisite phase 2/3 randomized controlled dementia prevention trial (MAP), a large multicenter clinical trial involving automated monitoring of atrial fibrillation (REACT AF), and a first-in-patient phase 2a biomarker and edema attenuation in intracerebral hemorrhage trial (BEACH).
Dr. Hanley has published over 400 peer-reviewed articles and book chapters, received the Humboldt Research Prize for accomplishments in brain injury research, and mentored nearly 100 researchers. His trainees, which include a large number of trialists, have led 25 brain intensive care units, and over 40 have been named full professors, program leaders, or department chairs. He has served on public boards including the American Academy of Neurology, National Stroke Association, and NIH National Institute of Nursing Research.
Recent News Articles and Media Coverage
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Decentralized Clinical Trials in the NCATS Trial Innovation Network. Decentralized Trials & Research Alliance (DTRA). July 26, 2024. Guest Speaker on DTRA podcast. (5) TGIF-DTRA: Decentralized Clinical Trials in the Trial Innovation Network | LinkedIn
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Could a clot-busting drug help treat a 'bleeding' stroke?, HealthDay News (Feb. 18, 2016)
Additional Academic Titles
Professor of Anesthesiology and Critical Care Medicine, Professor of Neurological Surgery
Contact for Research Inquiries
BIOS CTCC
750 E. Pratt St.
16th Floor
Baltimore, MD 21202
Honors
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Top 10 Clinical Research Achievement Awardee: Early COVID-19 Treatment with COVID-19 Convalescent Plasma, 2023
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Distinguished Investigator Award, Society of Critical Care Medicine, 2018
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Hans Chiari Memorial Lecture Award, Austrian Stroke Research Society, 2016
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Merril Spencer Award, Swedish Hospital, Seattle, WA, 2007
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Doctorate Honoris Causa, Ivane Javakhishvili Tbilisi State University, 2006
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Honorary Professor of Neurology, Georgian State Medical Academy, 2003
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Visionary in Practice Award, National Stroke Association, 2000
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Jeffrey and Harriet Legum Endowed Chair in Acute Care Neurology, Johns Hopkins University School of Medicine, 1999
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President's Citation Award, Society of Critical Care Medicine, 1997
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Alexander Humboldt Research Prize, Alexander von Humboldt Foundation, 1996
Memberships
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American Medical Association
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Member since 1980
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American Academy of Neurology
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Member since 1980; fellow status since 1995
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American Physiologic Society
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Honorific member
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National Stroke Association
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Member since 1998
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American Physiological Society
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Member since 1989
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Society of Critical Care Medicine
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Member since 1991
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American Neurological Association
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Elected member since 1991
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Society of Critical Care Medicine
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American Heart Association/American Stroke Association
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Stroke Council Fellow since 2001
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World Federation of Neurology
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Member since 1991
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European Stroke Organisation/World Stroke Organisation
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Member since 2016
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German Society for Neurocritical Care and Emergency Medicine (ANIM)
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Member since 1996
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Locations
- The Johns Hopkins Hospital
- 1800 Orleans Street, Baltimore, MD 21287
- phone: 410-955-5000
- fax: 410-955-5001
Expertise
Education
Johns Hopkins University School of Medicine
Fellowship, Neurology, 1983Johns Hopkins University School of Medicine
Residency, Neurology, 1981Weill Cornell Medical College
Medical Education, MD, 1975Board Certifications
Neurology
American Board of Psychiatry and Neurology, 1990Internal Medicine
American Board of Internal Medicine, 1978Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Humana
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- UnitedHealthcare
- Veteran Affairs Community Care Network (Optum-VACCN)