Zahra Maleki, MD

Primary Academic Title

Associate Professor of Pathology

Background

Videos

• Salivary Gland Cytology: A Practical Approach

Research Interests

Translational studies in lung neoplasms

Research Summary

Dr. Zahra Maleki is a cytopathologist with a particular interest in head and neck and lung neoplasms. She is investigating the role of human papilloma virus (HPV) in head and neck squamous cell carcinomas. She believes that further investigation of HPV and its pathway may initiate preventive measures in the future.

Google Scholar

http://scholar.google.com/citations?user=sQCk07IAAAAJ

Selected Publications

• *Bishop JA, *Maleki Z, Valsamakis A, Ogawa T, Chang X, Pai SI, Westra WH. Application of the hybrid capture 2 assay to squamous cell carcinomas of the head and neck: a convenient liquid-phase approach for the reliable determination of human papillomavirus status.  Cancer Cytopathol. 2012 Feb;120(1):18-25. doi: 10.1002/cncy.20175. *The first and second authors have contributed equally.

• Allison DB, Maleki Z. HPV-related Head and Neck Squamous Cell Carcinoma: An Update and Review Article. JASC. Pages 1-13.  DOI: http://dx.doi.org/10.1016/j.jasc.2015.12.001

• Allison DB, Miller JA, Coquia SF, Maleki Z. Ultrasonography-guided fine-needle aspiration with concurrent small core biopsy of neck masses and lymph nodes yields adequate material for HPV testing in head and neck squamous cell carcinomas. JASC. 1-2, 2016,  5 (1): 22–30. Http://dx.doi.org/10.1016/j.jasc.2015.06.002

• Bagby C, Ronnett BM, Yemelyanova A, Maleki Z, Kuhn E, Vang R. Clinically occult tubal and ovarian high-grade serous carcinomas presenting in uterine samples: diagnostic pitfalls and clues to improve recognition of tumor origin. Int J Gynecol Pathol 2013 Sep;32 (5), 433-443. doi: 10.1097/PGP.0b013e31826a6446.

• Book Chapters.      Zahra Maleki. Chapter 6: ERUS and ERUS-FNA of Intramural and Extramural Masses of the Colorectum. Cytology of the Mediastinum and Gut Via Endoscopic Ultrasound-Guided Aspiration”. Ricardo Bardales. Springer.

• Bovbel A, Zaheer A, Maleki Z. Cytomorphologic findings of intraosseous notochordal rest on touch Preparation: A Case Report. Diagnostic Cytopathology.  Diagn Cytopathol. 2015 Mar;43(3):243-6. doi: 10.1002/dc.23186.

• Ellis CL, Maleki Z, Ali SZ. Ectopic decidua in abdominal washings found intraoperatively at cesarean section. Diagn Cytopathol 2010 Oct;38(10):740-1.

• Feldman MJ, Prosciak M, Maleki Z, Milner SM. Gas Gangrene. J Surg Radiol. 2010 Oct 1;1(2)

• Ho CY, Maleki Z. Giant cell tumor of tendon sheath: cytomorphologic and radiologic findings in 41 patients. Diagn Cytopathol. 2012 Aug;40 Suppl 2:E94-8. doi: 10.1002/dc.22840. (selected as associated invited editorial and for bone and soft tissue special issue)

• Holmes B, Maleki Z, Westra W. The fidelity of p16 staining as a surrogate marker of human papillomavirus (HPV) status in fine needle aspirates and core biopsies of neck node metastases: Implications for HPV testing protocols. Acta Cytol 2015;59(1):97-103. doi: 10.1159/000375148.

• Holmes BJ, Subhawong AP, Maleki Z. Mycobacterial spindle cell pseudotumor: atypical mycobacterial infection mimicking malignancy on fine needle aspiration. Diagn Cytopathol 2014 Sep;42(9):772-4. doi: 10.1002/dc.23013.

• LeBlanc RE, Maleki Z. Herpes simplex viral cytopathic effect in urine cytology. Diagn Cytopathol 2013 Jan;41(1):61-2. doi: 10.1002/dc.21809.

• Li W, Maleki Z. Giant cell tumor of bone mimicking metastatic renal cell carcinoma: a case report. Diagn Cytopathol. 2012 Aug;40 Suppl 2:E169-71. doi: 10.1002/dc.21765.  (selected as associated invited editorial)

• Lisa M. Rooper, MD, Olga Nikolskaia, MD, Jamal Carter, MD, Yi Ning, MD, PhD, Ming-Tseh Lin, MD, PhD, and Zahra Maleki, MD.  A Single EBUS-TBNA Procedure Can Support a Large Panel of Immunohistochemical Stains, Specific Diagnostic Subtyping, and Multiple Gene Analyses in the Majority of Non-Small Cell Lung Cancer Cases. Human Pathology. doi:10.1016/j.humpath.2015.12.025. Available online 18 January 2016

• Maleki Z, Azmi F. Mycosis fungoides of the true vocal cord: a case report and review of the literature. Arch Iran Med. 2010 Sep;13(5):429-31.

• Maleki Z, Bailis AJ, Argani CH, Askin FB, Graham EM. Periventricular leukomalacia and  placental histopathologic abnormalities. Obstet Gynecol. 2009 Nov;114(5):1115-20.

• Maleki Z, Erozan Y, Geddes S, Li QK. Endorectal ultrasound-guided fine-needle aspiration: a useful diagnostic tool for perirectal and intraluminal lesions. Acta Cytol 2013;57 (1):9-18.

• Maleki Z, Kim HS, Thonse VR, Judson K, Vinh TN, Vang R. Uterine artery embolization with trisacryl gelatin microspheres in women treated for leiomyomas: a  clinicopathologic analysis of alterations in gynecologic surgical specimens. Int J Gynecol Pathol. 2010 May;29(3):260-8.

• Maleki Z, Loveless M, Fraig M. Coexistence of gonadoblastoma and dysgerminoma in a dysgenetic gonad on touch preparation: a case report. Diagn Cytopathol 2011 Jan;39(1):42-4.

• Maleki Z, Shariat S, Mokri M, Atri M. ER-negative /PR-positive Breast Carcinomas or Technical Artifacts in Immunohistochemistry? Arch Iran Med. 2012 Jun;15(6):366-9.

• Maleki Z. HPV Vaccination: Review Article and an Update.  World J Obstet Gynecol 5(1):16-27. doi: 10.5317/wjog.v5.i1.16. ISSN 2218-6220.

• Maleki Z.  Diagnostic issues with cytopathologic interpretation of lung neoplasms displaying high-grade basaloid or neuroendocrine morphology. Diagn Cytopathol. 2011 Mar;39(3):159-67. doi: 10.1002/dc.21351.

• Natalie Banet, Lisa M. Rooper, and Zahra Maleki. Metastatic HPV-related Head and Neck Squamous Cell Carcinoma to the Lung and Mediastinal Lymph Nodes in Aspirated Cytology Material: A Diagnostic Pitfall. Diagn Cytopathol. 2016 Mar;44(3):206-14. doi: 10.1002/dc.23425. Epub 2016 Jan 13.

• Olson MT, Novak A, Boonyaarunnate T, Trotter J, Sachs S, Kelly D,  Ford S, Cornish TC, Toll S, Tatsas AD, Maleki Z, Erozan YS, Rosenthal DL. Reproducibility of the Johns Hopkins Hospital template for urologic cytology samples. J Am Soc Cytopathol May-June 2014;3(3):156-64.

• Onur I, Crane GM, Maleki Z.  Cytomorphologic and Flow Cytometric Analysis of Cerebrospinal Fluid with T-Cell Lymphoma Involvement: A Retrospective Study of Rare Cases. Acta Cytol. 2015;59(4):325-31. doi: 10.1159/000439106. Epub 2015 Aug 29.

• Pindrik J, Macki M, Bydon M, Maleki Z, Bydon A. Midline synovial and ganglion cysts causing symptomatic lumbar stenosis: literature review and case series. World J Clin Cases 2013 Dec 16;1(9): 285–9. doi: 10.12998/wjcc.v1.i9.285.

• Rodic N, Maleki Z. Cytomorphologic findings of Schneiderian papilloma: a case report. Diagn Cytopathol 2012 Dec;40(12):1100-3. doi: 10.1002.

• Sathiyamoorthy S, Maleki Z. Cytomorphologic overlap of differentiated thyroid carcinoma and lung adenocarcinoma and diagnostic value of TTF-1 and TGB on cytologic material. Diagn Cytopathol 2014 Jan;42(1):5-10. doi: 10.1002/dc.22997.

• Sayah M, VandenBussche C, Maleki Z. Epithelioid hemangioendothelioma in pleural effusion. Diagn Cytopathol. 2015 Sep;43(9):751-5. doi: 10.1002/dc.23315. Epub 2015 Jul 17.

• Sheikh U, Rodic N, Maleki Z. Extramedullary hematopoiesis: cytomorphologic, histologic, and radiologic findings in 16 cases. Acta Cytol 2015;59(2):144-8. doi: 10.1159/000376602.

• Smith DF, Maleki Z, Coughlan D, Gooi Z, Akpeng B, Ogawa T, Bishop JA, Frick KD, Agrawal N, Gourin CG, Ha PK, Koch WM, Richmon JD, Westra WH, Pai SI. Human papillomavirus status of head and neck cancer as determined in cytologic specimens using the hybrid-capture 2 assay. Oral Onco. 2014 Jun;50(6):600-4.

• Tilson M, Maleki Z. Collagen balls in a cervical-vaginal smear: a case report. Diagn Cytopathol. 2011 Oct;39(10):760-1. doi: 10.1002/dc.21527

• Toll AD, Kelly D, Maleki Z.  Utility of P16 expression and Ki-67 proliferation index in ASCUS and ASC-H pap tests. Diagn Cytopathol 2014 Jul;42(7):576-81. doi: 10.1002/dc.23076.

• Toll AD, Maleki Z. Cytomorphology of non-small cell lung carcinoma (NSCLC) with anaplastic lymphoma kinase (ALK) gene rearrangement.  Diagn Cytopathol 2015 Jan;43(1):8-15. doi: 10.1002/dc.23160.

• VandenBussche CJ, Illei PB, Lin MT, Ettinger DS, Maleki Z. Molecular alterations in non-small cell lung carcinomas of the young human pathology. Hum Pathol 2014 Dec;45(12):2379-87. doi: 10.1016/j.humpath.2014.08.005. (Selected for Advanced PubMed)

• VandenBussche CJ, Maleki Z. Fine needle aspiration of squamous-lined cysts of the pancreas. Diagnostic Cytopatholog 2014 Jul;42(7):592-9. doi: 10.1002/dc.23080.

• VandenBussche CJ, Wakely P, Siddiqui M, Maleki Z, Ali S. Cytopathologic characteristics of epithelioid vascular malignancies. Acta Cytol 2014;58(4):356-66. doi: 10.1159/000366151.

• Vincent J, Maleki Z. Elastofibroma: cytomorphologic, histologic, and radiologic findings in five cases. Diagn Cytopathol. 2012 Aug;40 Suppl 2:E99-E103. doi: 10.1002/dc.21732. (selected as associated invited editorial and for bone and soft tissue special issue)

• Xu R, Solakoglu C, Maleki Z, McGirt MJ, Gokaslan ZL, Bydon A. Hemorrhagic synovial cyst: the possible role of initial trauma and subsequent microtrauma in its pathogenesis: case report. Neurosurgery 2011 Mar;68(3):E858-65; discussion E865.

• Zhao P, Maleki Z. Strongyloides stercoralis in bronchoalveolar lavage specimen processed as Prussian Blue Stain. Diagn Cytopathol 2013 Feb;41(2):141-3. doi: 10.1002/dc.21822.

• Zheng G, Ettinger DS, Maleki Z. Utility of the quantitative Ki-67 proliferation index and CD56 together in the cytologic diagnosis of small cell lung carcinoma and other lung neuroendocrine tumors.  Acta Cytol 2013;57(3):281-90.