Xiaobu Ye, MD, MS

Xiaobu Ye is a Professor of Neurosurgery and Oncology/Biostatistics at the Johns Hopkins School of Medicine (JHMI), the Director of Biostatistics in the Department of Neurosurgery.  She earned her degrees in medicine and an MS in Biostatistics in 1983 and 1994, respectively. She was a faculty member at the Medical University of South Carolina before joining the Division of Oncology Biostatistics at JHMI in 2002.

The main focus of her work has been implementing statistical methods in practical clinical research with an emphasis in clinical trials, relying heavily on scientific rationales in medicine, biology, and principles of statistics. Statistical methods include the continual reassessment method (CRM), the response surface method, an entropy-based approach, the Bayesian method, and other general statistical approaches to anti-cancer therapeutic development. 

Dr. Ye also served as a Senior Statistician for the Center for Complementary and Alternative Medicine and SPORE grants at Johns Hopkins. She served as the biostatistician for an NIH-founded Adult Brain Tumor Consortium (ABTC) for over 20 years, the formal Chair of Biostatistics of the Consortium. She also served as an elected member of the National Cancer Institution Brain Malignancies Steering Committee for over a decade and the Head and Neck Steering Committee's Metastatic-Recurrent Task Force for Biostatistics. 

She has more than 30 years of experience in application of statistical principles in medical, translational, and especially neurological diseases research and clinical trials.