Susan Eshleman, MD, PhD

Professional Titles

• Director, HIV Prevention Trials Network (HPTN) Laboratory Center

Primary Academic Title

Professor of Pathology

Background

Centers and Institutes

• AIDS Research, Center for
• Global Health, Center for

Clinical Trials Summary

HIV Prevention

Contact for Research Inquiries

720 Rutland Ave
Ross Building Room 646
Baltimore, MD 21205

Research Interests

evaluation of interventions for HIV prevention, HIV diversity, HIV transmission, disease progression, and treatment outcomes

Lab Website

HPTN (HIV Prevention Trials Network) Network Lab - Lab Website

• Dr. Eshleman's research program includes basic, translational, and clinical research.

Research Summary

Dr. Eshleman's research program includes basic, translational, and clinical research. Her basic research program is focused on HIV diversity and its impact on HIV transmission, disease progression, and treatment outcomes. Her translational research program is focused on development and evaluation of assays and laboratory methods for HIV analysis. Dr. Eshleman directs two CAP-accredited laboratories at JHU: the HIV Genotyping Laboratory and the HIV Clinical Research Laboratory. Her clinical research program is focused on HIV prevention. She is also the Director of the HPTN Laboratory Center, one of three leadership groups of the NIH-sponsored HIV Prevention Trials Network (HPTN). This network performs cohort studies and clinical trials evaluating behavioral, biomedical, and structural interventions for HIV prevention in the US, Africa, South America, Asia, and Eastern Europe.

Selected Publications

• Eshleman SH, Hudelson SE, Redd AD, Swanstrom R, Ou S-S, Zhang XC, Ping L-H, Piwowar-Manning E, Porcella SF, Sievers MF, Martens CA, Bruno D, Dukhovlinova E, McCauley M, Gamble T, Fogel JM, Sabin D, Quinn TC, Gunde L, Maliwichi M, NhandoN, Akelo V, Panchia R, Kumarasamy N, Chotirosniramit N, de Melo MG, Pilott J, Grinsztejn B, Mayer K, Chen YQ, Hughes JP, Cohen MS. Treatment as Prevention: Characterization of partner infections in the HIV Prevention Trials Network 052 trial. J AIDS. 2017; 74:112-116.

• Eshleman SH, Piwowar-Manning E, Wilson EA, Lennon D, Fogel JM, Agyei Y, Sullivan PA, Weng L, Moore A, Laeyendecker O, Kosloff B, Bwayla J, Maarman G, van Deventer A, Floyd S, Bock P, Ayles H, Fidler S, Hayes R, and Donnell D. Determination of HIV status and identification of incident HIV infections in a large, community-randomized trial: HPTN 071 (PopART). Clinicaltrial: LaboratoryLead. J Int AIDS Soc. 2/2020; 23(2)e25452.

• Coates TJ, Kulich M, Zelaya CE, Celantano DD, Chariyalertsak S, Chingono A, Gray G, Mbwambo JKK, Morin FS, Richter L, Sweat M, van Rooven H, McGrath N, Fiamma A, Laeyendecker O, Piwowar-Manning E, Szerekes G, Donnell D, and Eshleman SH. Effect of community-based voluntary counselling and testing on HIV incidence and social and behavioural outcomes (NIMH Project Accept; HPTN 043): a cluster-randomised trial. Lancet Global Health.2014. 2:e267-e277.

• Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour M, Kumarasamy N, Hakim JG, Kumwenda J, Grinsztejn B, Pilotto J, Godbole SV, Chariyalertsak S, Santos BR, Mayer KH, Hoffman IF, Eshleman SH, Piwowar-Manning E, Cottle L, Zhang XC, Makhema J, Mills LA, Panchia R, Faesen S, Eron J, Gallant J, Havlir D, Swindells S, Elharrar V, Burns D, Taha TE, Nielse-Saines K, Celentano DD, Essex M, Hudelson SE, Redd AD, and Fleming TR. Antiretroviral treatment for prevention of HIV transmission: The final results of the HIV Prevention Trials Network (HPTN) 052 trial. NewEngJMed. 2016; 375:830-839.

• Zhang Y, Wymant C, Laeyendecker O, Grabowski MK, Hall M, Hudelson S, Piwowar-Manning E, McCauley M, Gamble T, Hosseinipour M, Kumarasamy N, Hakim JG, Kumwenda J, Mills LA, Santos BR, Grinsztejn, Pilotto JH, Chariyalertsak S, Makhema J, Chen YQ, Cohen MS, Fraser C, and Eshleman SH. Evaluation of phylogenetic analysis for inferring the direction of HIV transmission. Clin Infect Dis. 2020; ciz1247, https://doi.org/10.1093/cid/ciz1247.

Honors

• Poster Award for Outstanding Content and Presentation, 5th International Workshop on HIV Drug Resistance and Treatment Strategies, 1/1/01
• Faculty Teaching Award, Department of Pathology, The Johns Hopkins University, 1/1/00
• MetPath Fellowship in Laboratory Medicine, MetPath Inc., 1/1/92
• ACLPS Young Investigator Award for Excellence in Research, 1/1/92
• Upjohn Achievement Award for Excellence in Biomedical Research, 1/1/87
• Association of M.I.T. Alumnae Senior Academic Award, 1/1/80

Graduate Program Affiliations

• Cellular and Molecular Medicine

  Pathobiology

Professional Activities

• HIV Clinical Research Laboratory, Director
• HIV Genotyping Laboratory, Director