Sudath Hapuarachchige, MS, PhD

Highlights

Languages

English

Gender

Male

Johns Hopkins Affiliations:

Johns Hopkins School of Medicine Faculty

About Sudath Hapuarachchige

Primary Academic Title

Assistant Professor of Radiology and Radiological Science

Background

Sudath Hapuarachchige, Ph.D. is an Assistant Professor of Radiology and Radiological Science in Johns Hopkins University School of Medicine. Dr. Hapuarachchige received his Bachelor of Science (B.Sc.) degree from the Department of Chemistry, University of Colombo and accomplished his MS and Ph.D. in synthetic organic chemistry in the Department of Chemistry and Biochemistry, New Mexico State University, USA. Dr. Hapuarachchige's research is focused on the development of (a) image-guided drug delivery systems for theranostic applications in cancer therapy, (b) novel chemical strategies for smart-release of drugs, and (c) antibody-drug conjugates for efficacious drug delivery. Dr. Hapuarachchige is the recipient of Alfred Blalock Young Investigator Award in 2015 and Outstanding Young Faculty in Research Award in 2020 from the Johns Hopkins University School of Medicine.

Centers and Institutes

Sidney Kimmel Comprehensive Cancer Center

Additional Academic Titles

Assistant Professor of Oncology

Contact for Research Inquiries

720 Rutland Avenue
Traylor 217-F
Baltimore, MD 21205

shapuar1@jh.edu

Research Interests

Development of image-guided and targeted drug delivery systems as theranostics for cancer therapy, Development of novel chemical strategies for smart-release of drugs

Selected Publications

Hapuarachchige S, Huang CT, Donnelly MC, Ba?inka C, Lupold SE, Pomper MG, Artemov D. Cellular Delivery of Bioorthogonal pretargeting therapeutics in PSMA-positive prostate cancer. Mol Pharm. 2020; 17(1): 98-108
Hapuarachchige S, Kato Y, Artemov D. Bioorthogonal two-component drug delivery in HER2(+) breast cancer mouse models. Sci Rep. 2016; 6: 24298
Hapuarachchige S, Montaño G, Ramesh C, Rodriguez D, Henson LH, Williams CC, Kadavakkollu S, Johnson DL, Shuster CB, Arterburn JB. Design and synthesis of a new class of membrane-permeable triazaborolopyridinium fluorescent probes. J Am Chem Soc. 2011; 133(17): 6780-6790
Hapuarachchige S, Zhu W, Kato Y, Artemov D. Bioorthogonal, two-component delivery systems based on antibody and drug-loaded nanocarriers for enhanced internalization of nanotherapeutics. Biomaterials. 2014; 35(7): 2346-2354
Huang CT, Guo X, Ba?inka C, Lupold SE, Pomper MG, Gabrielson K, Raman V, Artemov D, Hapuarachchige S. Development of 5D3-DM1: A novel anti-prostate-specific membrane antigen antibody-drug conjugate for PSMA-positive prostate cancer therapy. Mol Pharm. 2020; 17(9): 3392-3402

Honors

Outstanding Young Faculty in Research, Johns Hopkins Medicine, Radiology, 10/12/20
Best Poster in Radiology Research, JHU, 12/7/18
Best Research Image, JHU, 4/24/18
Best Poster in Radiology Research, JHU, 12/12/17
Alfred Blalock Young Investigator Award, JHU, 4/14/15
Magna cum Laude Award (Molecular Imaging), ISMRM, 4/5/15
Educational Trainee Award, ISMRM, 3/4/15
Ruth D. Vogel Professional Development Award, JHU, 1/8/14
Summa cum laude award (Targeted drug delivery), ISMRM, 5/7/13
Faculty scholars in cancer research, AACR, 4/24/13
Educational Trainee Award, ISMRM, 3/6/13
Educational Trainee Award, ISMRM, 3/1/12
Honors graduate award for outstanding academic achievement, NMSU, 7/1/10
ACS Travel Award, American Chemical Society, 8/1/09
Honors graduate award for outstanding academic achievement, NMSU, 5/6/06