Shaoyong Yu, MD
Highlights
Languages
- English
Gender
MaleJohns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Shaoyong Yu
Primary Academic Title
Associate Professor of Medicine
Background
Dr. Shaoyong Yu is an Associate Professor of Medicine in the Division of Gastroenterology and Hepatology, Department of Medicine. His studies focus on neurogastroenterology and motility disorders.
Dr. Yu received medical and master’s degrees from Yichang and Tongji Medical Colleges, and a master of public health (MPH) degree from the Johns Hopkins Bloomberg School of Public Health. Before joining the Johns Hopkins faculty, he completed three-year research fellowship training at Johns Hopkins University School of Medicine, focusing on gastrointestinal motility disorders, plus an additional two-year postdoctoral training in sensory neurobiology at JHU.
Centers and Institutes
- Conte Digestive Diseases Basic and Translational Research Core Center
- Motility and Neurogastroenterology
Contact for Research Inquiries
Phone: (410) 502-2455
syyu@jhmi.edu
Lab Website
Shaoyong Yu Lab
The research projects in my lab focus on sensory neurobiology (vagal afferent nerve function) and mast cell-nerve interactions in the esophagus.
A NIH-funded post-doc position is opening to investigate the molecular and cellular mechanisms of mast cell-nerve interactions in the esophagus for self-motivated individual who has been trained in neurobiology and/or immunology.
Research Summary
Our research projects focus on sensory afferent neurobiology and nerve-immune interactions in the GI tract. Specifically, we are interested in studying the cellular and molecular mechanisms underlying vagal afferent nerve activation and mast cell activation-induced sensitization of vagal nociceptive afferents in the esophagus.
For research inquiries please contact Dr. Yu via email at syyu@jhmi.edu.
Selected Publications
Hu Y, Liu Z, Yu X, Pasricha PJ, Undem BJ, Yu S. Increased acid responsiveness in vagal sensory neurons in a guinea pig model of eosinophilic esophagitis. Am J Physiol Gastrointest Liver Physiol. 2014 Jul 15;307(2):G149-57
Patil MJ, Huang Y, Yu M, Dong X, Undem BJ, Yu S. Ginger Constituent 6-Shogaol Attenuates Vincristine-Induced Activation of Mouse Gastroesophageal Vagal Afferent C-Fibers. Molecules. 2022 Nov 2;27(21):7465
Yu X, Hu Y, Yu S. Effects of acid on vagal nociceptive afferent subtypes in guinea pig esophagus. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15;307(4):G471-8
Yu X, Hu Y, Yu M, Undem BJ, Yu S. Deoxycholic acid activates and sensitizes vagal nociceptive afferent C-fibers in guinea pig esophagus. Am J Physiol Gastrointest Liver Physiol. 2021 Aug 1;321(2):G149-G156
Yu X, Yu M, Liu Y, Yu S. TRP channel functions in the gastrointestinal tract. Semin Immunopathol. 2016 May;38(3):385-96
Additional Training
- Johns Hopkins University School of Medicine, Division of Gastroenterology and Hepatology, Baltimore, MD, Clinical Research Fellow
- Johns Hopkins University School of Medicine, Division of Allergy and Clinical Immunology, Baltimore, MD, Post-doctoral Fellow