Shanshan Jiang, MD, PhD

Highlights

Languages

English

Gender

Female

Johns Hopkins Affiliations:

Johns Hopkins School of Medicine Faculty

About Shanshan Jiang

Primary Academic Title

Associate Professor of Radiology and Radiological Science

Background

Dr. Jiang’s research interest has focused on developing and applying novel MRI methodologies to neurological diseases. Before she joined Hopkins, Dr. Jiang was a trained radiologist with a specialty in neuroimaging. As a Trainee and Postdoctoral Fellow at Johns Hopkins, she implemented the protein-based Amide Proton Transfer- (APT) MRI approach, a specific type of Chemical Exchange Saturation Transfer (CEST) imaging, for imaging of brain tumor and other neurological diseases. Her most recent research includes the development of APTw MRI-guided stereotactic biopsy and the validation of the pathology underlying the APT contrast in gliomas, as well as radio genomics using APT MRI and machine learning in glioma patients, an important research area of precision medicine. Dr. Jiang published in vivo CEST/APT imaging studies in both animals and humans in recent years.

Her most recent paper about APT image-guided brain tumor stereotactic biopsy published in European J. Cancer received a highly enthusiastic review. This is an important study with significant clinical implications demonstrating the potential of APTw imaging in neuro-oncology. At Johns Hopkins, Dr. Jiang has established a multidisciplinary research team consisting of computer scientists, MRI scientists, clinicians, and biostatisticians. The overall goal of her research is to push the APT MRI methodology research and clinical applications to brain tumor and other neurological diseases and the entire CEST-MRI field to a whole new level.

Additional Academic Titles

Associate Professor of Oncology

Selected Publications

Jinyuan Zhou, Hye-Young Heo, Linda Knutsson, Peter C.M. van Zijl, and Shanshan Jiang. APT-weighted MRI: Techniques, current neuro applications, and challenging issues. J. Magn. Reson. Imaging. 50, 347-364 (2019). PMC6625919.
Shanshan Jiang, Charles G. Eberhart, Michael Lim, Alfredo Quinones-Hinojosa, Huamin Qin, Hye-Young Heo, Yi Zhang, Lindsay Blair, Zhibo Wen, Matthias Holdhoff, Peng Huang, Jon D. Weingart, Peter B. Barker, Martin G. Pomper, John Laterra, Peter C.M. van Zijl, Jaishri O. Blakeley, and Jinyuan Zhou. Identifying Recurrent Malignant Glioma after Treatment Using Amide Proton Transfer-Weighted MR Imaging: A Validation Study with Image-Guided Stereotactic Biopsy. Clin. Cancer Res. 25, 552-561 (2019). PMC6335169.
Shanshan Jiang, Charles G. Eberhart, Yi Zhang, Hye-Young Heo, Zhibo Wen, Lindsay Blair, Huamin Qin, Michael Lim, Alfredo Quinones-Hinojosa, Jon D. Weingart, Peter B. Barker, Martin G. Pomper, John Laterra, Peter C.M. van Zijl, Jaishri O. Blakeley, and Jinyuan Zhou. Amide Proton Transfer-Weighted MR Image-Guided Stereotactic Biopsy in Patients with Newly Diagnosed Gliomas. Eur. J. Cancer. 83, 9-18 (2017). PMC5572540.
Shanshan Jiang, Tianyu Zou, Charles G. Eberhart, Maria A.V. Villalobos, Hye-Young Heo, Yi Zhang, Yu Wang, Xianlong Wang, Hao Yu, Yongxing Du, Peter C.M. van Zijl, Zhibo Wen, Jinyuan Zhou. Predicting IDH mutation status in grade II gliomas using amide proton transfer-weighted (APTw) MRI. Magn. Reson. Med. 78, 1100-1109 (2017). PMC5561497.
Guo P, Wang P, Yasarla R, Zhou J, Patel VM, Jiang S. Anatomic and molecular MR image synthesis using confidence guided CNNs. _IEEE Trans Med Imagi_ng. 40, 2832-2844 (2021). PMC8543492.

Honors

The most cited papers in 2016 J. Magn. Reson. Imaging: Bo Ma, et al. 44, 452-462 (2016), 27th ISMRM Annual Meeting, 1/1/19
Featured in the social media spotlight, Academy for Radiology & Biomedical Imaging Research, 1/1/19
One oral presentation (p. 0894) awarded the Summa Cum Laude Merit Award (top 3%) and one oral presentation (p. 0410) awarded the Magna Cum Laude Merit Award (top 15%), 26th ISMRM Annual Meeting, 1/1/18
Junior Fellow, International Society of Magnetic Resonance in Medicine (ISMRM), 1/1/18
1st Place Abstract Award in Radiology Department Research Day, Johns Hopkins University School of Medicine, 1/1/17
One oral presentation (p. 2316) awarded the Magna Cum Laude Merit Award (top 15%), 25th ISMRM Annual Meeting, 1/1/17
2nd Place Award in MR in Drug Development Study Group for one oral presentation (p. 0720), 25th ISMRM Annual Meeting, 1/1/17
Winner of the student travel award for young investigators, 102nd Radiological Society of North America (RSNA) Annual Meeting, 1/1/16
Two oral presentations (p. 0230 and p. 0805) awarded the Summa Cum Laude Merit Award (top 3%) and one oral presentation (p. 0288) awarded the Magna Cum Laude Merit Award (top 15%), 24th ISMRM Annual Meeting, 1/1/16
Travel Grant, XXII World Congress of Neurology (MCN 2015), 1/1/15
Student Stipend, International Society of Magnetic Resonance in Medicine (ISMRM), 1/1/15
Yale-China Association Scholarship, Xiangya School of Medicine, 1/1/04

Memberships

Radiological Society of North America (RSNA)
International Society of Magnetic Resonance in Medicine (ISMRM)
American College of Radiology (ACR)
National Neurotrauma Society (NNS)
Institute of Electrical and Electronics Engineers (IEEE)