Kay Li, MD, PhD
Anatomic Pathology
Highlights
Johns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Kay Li
Primary Academic Title
Professor of Pathology
Background
Dr. Qing Kay Li is a professor of pathology and oncology at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include surgical pathology and cytopathology.
Dr. Li received her medical degree from Tianjin Medical University, and completed her pathology resident training at Albany Medical College, surgical pathology fellowship at University Hospital of Cleveland, and cytopathology fellowship at the University of Michigan Hospital. She also had a Ph.D. and cell biology fellowship training at the Cleveland Clinic Foundation.
Dr. Li is also a faculty member and co-PI at the Johns Hopkins Biomarker Discovery Center, and NIH/NCI Clinical Proteomic Tumor Analysis Consortium (CPTAC). Her research interests focus on the application of advanced cellular and molecular techniques to the field of cytopathology and cancer biology, particularly in the field of proteogenomic characterization of lung, stomach and prostate cancer.
Dr. Li serves as editorial board member and associated editors for several journals, committee member of the American Society of Cytopathology, and study sections of government agents and private organizations. She has more than 140 publications, including book chapters and books. Her work has been presented at many national/international meetings.
Additional Academic Titles
Professor of Oncology
Contact for Research Inquiries
600 N Wolfe Street, PATH 404
Department of Pathology
Baltimore, MD 21287
Phone: (410) 955-1180
Research Interests
Early detection of lung, stomach and prostate cancer, Genetic biomarkers, Lung and stomach cancer
Research Summary
Dr. Qing Kay Li’s research focuses on the early detection of lung, stomach and prostate cancers and ways to separate aggressive from non-aggressive tumors using state-of-the-art molecular tools.
Recently, Dr. Li and her team identified hundreds of proteins and genetic biomarkers in the airway fluid (bronchoalveolar lavage) from lung cancer patients. Their preliminary data shows that these protein and genetic biomarkers have the potential to improve the accuracy of current lung cancer screening tests and could play a role in the early detection of lung cancers, particularly in patients with small lung nodules.
Google Scholar
https://scholar.google.com/citations?hl=en&user=eZpNCggAAAAJ&view_op=list_works&cstart=
Selected Publications
Gillette MA, Satpathy S, Cao S, Dhanasekaran SM, Vasaikar S, Krug K, Petralia F, Li Y, Liang WW, Reva B, Krek A, Ji J, Song X, Liu W, Hong R, Yao L, Blumenberg L, Savage S, Wendl M, Wen B, Li K, Tang L, MacMullanM, Avanessian S, Kane HM, Newton C, Kothadia RB, Ma W, Yoo S, Mannan R, Vats P, Kawaler E, Omelchenko T, Colaprico A, Geffen Y, Maruvka Y, Leprevost F, Veluswamy R, Hostetter G, Heiman D, Wyczalkowski MA, Kinsinger CR, Boja ES, Omenn GS, Chinnaiyan AM, Rodriguez H, Li QK, Jewell S, Thiagarajan M, Getz G, Zhang B, Fenyo D, Ruggles K, Cieslik M, Robles A, Clauser KC, Govindan R, Wang P, Nesvizhskii A, Ding L, Mani DR, Carr SA. CPTAC. Proteogenomic characterization reveals therapeutic vulnerabilities in lung adenocarcinoma. Cell. 2020;182:200-225
Hoti N, Lih TS, Pan JB, Zhou YY, Yang GL, Deng A, Chen LJ, Dong MM, Yang RB, Tu CF, Haffner MC, Li QK, Zhang H. A comprehensive analysis of FUT8 overexpressing prostate cancer cells reveals the role of EGFR in castration resistance. Cancers. 2020;12:468
Zhou YY, Lih TSM, Höti N,Dong MM, Cao LW, Hu YW, Cho KC, Chen SY, Equez RV, Gabrielson E, Chan DW, Zhang H, Li QK. Proteomic signatures of 16 major types of human cancer reveal universal and cancer-specific proteins for the identification of potential therapeutic targets. Journal of Hematology & Oncology. 2020;13(1):170
Zhou YY, Lih TSM, Yang GL, Chen SY, Chen LJ, Zhang H, Li QK*. An integrated workflow for global, glycol- and phospho-proteomic analysis of tissue tissues. Anal. Chem. 2020;92:1842-1849
Zhou YY, Yang WM, Ao MH, Hoti N, Gabrielson E, Chan DW, Zhang H, Li QK*. Proteomic analysis of the Air-way fluid in lung cancer. Detection of periostin in bronchoalveolar lavage (BAL). Front Oncol. 2020;10:1072
Locations
- Johns Hopkins Bayview Medical Center
- 4940 Eastern Avenue, Baltimore, MD 21224
- phone: 410-550-0100
- fax: 410-550-0101
- The Johns Hopkins Hospital
- 1800 Orleans Street, Baltimore, MD 21287
- phone: 410-955-5000
- fax: 410-955-5001
Expertise
Education
University Hospitals Cleveland Medical Center
Fellowship, Pathology, 2006University of Michigan Medicine
Fellowship, Cytopathology, 2005Albany Medical Center
Residency, Pathology, 2004Cleveland State University
Graduate School, Biology, PhD, 1996Tianjin Medical University
Fellowship, Internal Medicine, 1988Tianjin Medical University
Residency, Internal Medicine, 1987Tianjin Medical University
Medical Education, MD, 1983Board Certifications
Cytopathology
American Board of Pathology, 2007Anatomic Pathology
American Board of Pathology, 2005Clinical Pathology
American Board of Pathology, 2005Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Humana
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- UnitedHealthcare
- Veteran Affairs Community Care Network (Optum-VACCN)