Manisha Aggarwal, MSE, PhD
Highlights
Languages
- English
Gender
FemaleJohns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Manisha Aggarwal
Primary Academic Title
Associate Professor of Radiology and Radiological Science
Background
Manisha Aggarwal, Ph.D., is an Associate Professor in the Department of Radiology and Radiological Science at the Johns Hopkins University School of Medicine.
Dr. Aggarwal is an investigator whose research focuses on high-field magnetic resonance imaging (MRI) techniques, advanced diffusion micro-imaging and acquisition methods, pre-clinical MRI, and the applications of these techniques for brain imaging.
Dr. Aggarwal earned Ph.D. and M.S.E. degrees in biomedical engineering from the Johns Hopkins University School of Medicine. She holds a Bachelor of Technology (Honors) degree in instrumentation engineering and a minor in electronics and electrical communication engineering from the Indian Institute of Technology, Kharagpur. She completed her post-doctoral research in Radiology at Johns Hopkins University.
Dr. Aggarwal is a Siebel Scholar and a Junior Fellow of the International Society for Magnetic Resonance in Medicine.
Contact for Research Inquiries
720 Rutland Avenue
217 Traylor Building
Baltimore, MD 21205
Research Interests
Brain Atlases, Diffusion MRI, High-field MRI Acquisition Techniques, Neurodegenerative Diseases, Neuroimaging, Oscillating Gradient Diffusion MRI, Pre-clinical MRI, Susceptibility Imaging
Research Summary
Dr. Aggarwal's research focuses on advanced magnetic resonance imaging (MRI) techniques and their applications to mapping of brain tissue microstructure in the human brain and in pre-clinical models. Her primary research areas include:
1. High-field diffusion micro-imaging techniques and pulse sequences
2. Characterization of brain tissue microstructure using diffusion and susceptibility MR methods
3. Oscillating gradient diffusion MRI and its applications to animal models of neurological disorders
4. High-resolution neuroimaging and development of computational brain atlases
Selected Publications
Aggarwal M., Jones MV., Calabresi PA., Mori S., Zhang J. Probing mouse brain microstructure using oscillating gradient diffusion MRI. Magn Reson Med. 2012 Jan 67(1):98-109.
Aggarwal M., Nauen DW., Troncoso JC., Mori S. Probing region-specific microstructure of human cortical areas using high angular and spatial resolution diffusion MRI. Neuroimage. 2015 Jan 15;105:198-207.
Aggarwal M., Zhang J., Pletnikova O., Crain B., Troncoso J., Mori S. Feasibility of creating a high-resolution 3D diffusion tensor imaging based atlas of the human brainstem: a case study at 11.7 T. Neuroimage. 2013 Jul 1;74:117-27.
Aggarwal M., Kageyama Y., Li X., van Zijl P. B0-orientation dependent magnetic susceptibility-induced white matter contrast in the human brainstem at 11.7T. Magn Reson Med. 2016 Jun;75(6):2455-66
Aggarwal M., Smith MD, Calabresi PA. Diffusion-time dependence of diffusional kurtosis in the mouse brain. Magn Reson Med. 2020;84(3):1564-1578
Honors
- Outstanding Junior Faculty Research Award, Johns Hopkins Radiology, 2019
- Junior Fellow, International Society for Magnetic Resonance in Medicine (ISMRM), 2013
- Siebel Scholar, 2012
- Phi Beta Kappa, 2012
- Finalist, ISMRM I. I. Rabi Young Investigator Award, 2010
Lectures & Presentations
- Application of diffusion MRI in animal models, Educational course, ISMRM Annual Meeting, 4/22/17
- Diffusion microimaging and brain tissue microstructure, Invited lecture - ICMRM Annual Meeting, 8/4/21
- How small is small? Probing very small compartment size - short diffusion time, Educational course, ISMRM Annual Meeting, 6/17/18
- Mesoscale imaging to micro-imaging and beyond: probing length scales in the brain with diffusion MRI, Lecture - Oxford University Autumn School in Neuroscience, 9/29/20
- Pre-clinical and postmortem diffusion imaging, Educational course - Organization for Human Brain Mapping (OHBM) Annual Meeting, 6/14/15
Memberships
- International Society for Magnetic Resonance in Medicine
- Organization for Human Brain Mapping
- Society for Neuroscience
Professional Activities
- Associate Editor - Frontiers in Oncology, 2020-
- Member, ISMRM Trainee Advisory Working Group, 2013 - 2014
- Program Committee Member, MICCAI Workshop on Computational Diffusion MRI, 2018 - 2020