Laura Ensign-Hodges, PhD
- Johns Hopkins School of Medicine Faculty
Languages
- English
Gender
FemaleAbout Laura Ensign-Hodges
Professional Titles
- Marcella E. Woll Professor of Ophthalmology
Primary Academic Title
Professor of Ophthalmology
Background
Laura Ensign, Ph.D., is the Vice Chair for Research and the Marcella E. Woll Professor of Ophthalmology at the Wilmer Eye Institute (Nanomedicine Division). Dr. Ensign has secondary appointments in Chemical and Biomolecular Engineering, Biomedical Engineering, Pharmacology and Molecular Sciences, Gynecology and Obstetrics, Infectious Diseases, and Oncology. Her research interests are in the area of nanomedicine. Her laboratory focuses on the characterization of biological barriers in health and disease in order to design more effective formulations for prophylactic and therapeutic drug delivery.
Centers and Institutes
Recent News Articles and Media Coverage
Game-Changer: How a Simple Quest Led to a Discovery That Promises to Change Lives, Wilmer Insider (Mar. 2021)
Additional Academic Titles
Professor of Gynecology and Obstetrics, Professor of Pharmacology and Molecular Sciences, Professor of Biomedical Engineering, Professor of Oncology, Professor of Medicine
Contact for Research Inquiries
400 N. Broadway
Smith 6015
Baltimore, MD 21287
Phone: (410) 614-9854
Research Interests
Drug delivery systems, Nanomedicine
Selected Publications
Hsueh TH, Chou RT, Rai U, Liyanage WS, Appell MB, Davison C, Kolodziejski P, Mozzer A, Leo KT, Kwon HY, Kim YC, Pitha I, Hanes J, Cummings MP, Ensign LM. Machine learning-driven multifunctional peptide engineering for sustained ocular drug delivery, Nat Comm, 2023;14:2509
Hsueh TH, Kim YC, Pitha I, Shin MD, Berlinicke CA, Chou RT, Kimball E, Schaub J, Quillen S, Leo KT, Han H, Xiao A, Kim Y, Appell MB, Rai U, Kwon H, Kolodziejski P, Ogunnaike L, Anders NA, Hemingway A, Jefferys J, Date AA, Eberhart C, Johnson TV, Quigley HA, Zack DJ, Hanes J, Ensign LM. Ion-complex microcrystal formulation provides sustained delivery of a multimodal kinase inhibitor from the subconjunctival space for protection of retinal ganglion cells, Pharmaceutics, 2021; 13(5):647
Josyula A, Omiadze R, Parikh KS, Kanvinde P, Appel MB, Patel P, Saeed H, Sutar Y, Anders NA, He P, Rudek M, McDonnell PJ, Hanes J, Date A, Ensign LM. An ion-paired moxifloxacin nanosuspension eye drop provides improved prevention and treatment of ocular infection, BioTM, 2021; 6(3):e10238
Kim YC, Shin M, Hackett S, Hsueh TH, Lima e Silva R, Date A, Han H, Kim BJ, Xiao A, Kim Y, Ogunnaike L, Anders NA, Hemingway A, He P, Jun AS, McDonnell PJ, Eberhart C, Pitha I, Zack DJ, Campochiaro PA, Hanes J, Ensign LM. Gelling hypotonic polymer solution for extended topical drug delivery to the eye, Nature Biomedical Engineering, 2020; 4(11):1053-1062
Patents
- US Patents 9,056,057; 9,393,212; 9.393,213; 9,415,020; 9,532,955; 9,737,491; 10,092,509; 10,058,511; 10,485,757; 10,646,434B2; 10,668,025; 10,736,854B2
- AU2011323250B2; CN104936620A; AU2013209452B2; RU2598627C2; K101811918B1; AU2016200707B2; CA2863632C; AU2016211696; AU2013256130B2; JP6360039B2; EP2635254B1; EP2804632B1; CA2816997C; CA2974715A1; AU2018201772B2; JP6816065B2
Honors
- Controlled Release Society Young Investigator Award
- Controlled Release Society College of Fellows
- Controlled Release Society Rising Women in Science Award
- AIMBE Fellow, American Institute of Medical and Biological Engineering, 3/30/20
- NAI Fellow, National Academy of Inventors, 12/1/19
- Outstanding Engineering Alumni Award, Texnikoi (Ohio State University Engineering Alumni Association), 10/6/19
- Maryland E-Nnovation Initiative Fund (MEIF) Award, State of Maryland, 6/1/18
- RPB Sybil B. Harrington Special Scholar Award, Research to Prevent Blindness, 6/1/17
- Maryland Outstanding Young Engineer, Maryland Academy of Sciences, 10/1/15
Graduate Program Affiliations
Chemical and Biomolecular Engineering; Biomedical Engineering; Pharmacology and Molecular Sciences