Highlights
Johns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Laura Cappelli
Professional Titles
- Co-Director, Immune-Related Toxicity Team
Primary Academic Title
Associate Professor of Medicine
Background
Dr. Laura Cappelli is an Associate Professor of Medicine and Oncology at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include rheumatology and adverse effects from cancer immunotherapy.
Dr. Cappelli earned her M.D. from Johns Hopkins. She completed her residency in internal medicine and performed a fellowship in rheumatology at the Johns Hopkins Hospital. She has a MHS in Clinical Investigation from the Johns Hopkins Bloomberg School of Public Health.
Dr. Cappelli focuses on immune related adverse events due to cancer immunotherapy and all forms of inflammatory arthritis. She co-directs the Immune-related toxicity team which provides clinical, research and educational support for immune related adverse events. Her primary research interest is inflammatory arthritis due to immune checkpoint inhibitor therapy. She also studies rheumatoid arthritis.
Recent News Articles and Media Coverage
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Patient Care at the Intersection of Rheumatology and Neurology, Rheumatology Advisor (February 11, 2022)
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5 Tips for Getting the Most Out of Your next Rheumatoid Arthritis Appointment, Self.com (3/10/2021)
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What to Ask a Doctor if You Get a Rheumatoid Arthritis Diagnosis, People.com (9/25/2020)
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Ultrasound Provides Insights into Immune Checkpoint Inhibitor-Induced Inflammatory Arthritis, The Rheumatologist (10/12/2020)
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Arthritis Emerges After Cancer Immunotherapy, Medpage Today, (June 17, 2016)
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Checkpoint Inhibitors Linked to Inflammatory Arthritis, Medscape (June 29, 2016)
Additional Academic Titles
Associate Professor of Oncology
Contact for Research Inquiries
5501
Hopkins Bayview Circle, Suite 1B1
Baltimore, MD 21224
Research Interests
Arthritis, Inflammation, Rheumatology
Research Summary
Dr. Cappelli has started a research program to evaluate the rheumatologic adverse effects of cancer immunotherapy. Immune checkpoint inhibitors, work to boost patients’ own immune systems to fight their cancer, leading to great advances in treatment. However, they can also lead to adverse events as a result of their mechanism of action. Rheumatologists are seeing patients with inflammatory arthritis, immune-mediated dry mouth and dry eyes, myositis, vasculitis and other adverse events due to cancer immunotherapy. Dr. Cappelli is investigating several different aspects of these adverse events including the clinical characteristics, epidemiology, impact on patients, and the biologic mechanisms. Her work involves collaborations with oncologists and laboratory investigators in rheumatology and oncology. Through this research, guidelines for evaluation and management of adverse events can be developed and those at greatest risk for adverse events may be identified.
Dr. Cappelli also has a research interest in rheumatoid arthritis. She focuses on the use of autoantibodies as biomarkers and on patients with seronegative rheumatoid arthritis.
PubMed
Selected Publications
Cappelli LC, Bingham CO 3rd. Spectrum and impact of checkpoint inhibitor-induced irAEs. Nat Rev Rheumatol. 2021 Feb;17(2):69-70. doi: 10.1038/s41584-020-00546-2. PubMed PMID: 33235330
Cappelli LC, Gutierrez AK, Baer AN, Albayda J, Manno RL, Haque U, Lipson EJ, Bleich KB, Shah AA, Naidoo J, Brahmer JR, Le D, Bingham CO 3rd. Inflammatory arthritis and sicca syndrome induced by nivolumab and ipilimumab. Ann Rheum Dis. 2017 Jan;76(1):43-50. doi: 10.1136/annrheumdis-2016-209595. Epub 2016 Jun 15. PubMed PMID: 27307501; PubMed Central PMCID: PMC5333990
Cappelli LC, Konig MF, Gelber AC, Bingham CO 3rd, Darrah E. Smoking is not linked to the development of anti-peptidylarginine deiminase 4 autoantibodies in rheumatoid arthritis. Arthritis Res Ther. 2018 Mar 23;20(1):59. doi: 10.1186/s13075-018-1533-z. PubMed PMID: 29566742; PubMed Central PMCID: PMC5865363
Braaten TJ, Brahmer JR, Forde PM, Le D, Lipson EJ, Naidoo J, Schollenberger M, Zheng L, Bingham CO, Shah AA, Cappelli LC. Immune checkpoint inhibitor-induced inflammatory arthritis persists after immunotherapy cessation. Ann Rheum Dis. 2020 Mar;79(3):332-338. doi: 10.1136/annrheumdis-2019-216109. Epub 2019 Sep 20. PubMed PMID: 31540935; PubMed Central PMCID: PMC7031780
Naidoo J, Zhang J, Lipson EJ, Forde PM, Suresh K, Moseley KF, Mehta S, Kwatra SG, Parian AM, Kim AK, Probasco JC, Rouf R, Thorne JE, Shanbhag S, Riemer J, Shah AA, Pardoll DM, Bingham CO, Brahmer JR, Cappelli LC. A Multidisciplinary Toxicity Team for Cancer Immunotherapy-Related Adverse Events. J Natl Compr Canc Netw. 2019 Jun 1;17(6):712-720. doi: 10.6004/jnccn.2018.7268. PubMed PMID: 31200355
Memberships
- American College of Rheumatology
Locations
- Johns Hopkins Bayview Medical Center
- 4940 Eastern Avenue, Bayview Medical Offices, Level 01 (G), Clinic 5, Baltimore, MD 21224
- phone: 443-997-1552
- fax: 410-550-1033
Expertise
Education
Johns Hopkins University School of Medicine
Fellowship, Rheumatology, 2016Johns Hopkins Bloomberg School of Public Health
Graduate School, MHS, 2015Johns Hopkins University School of Medicine
Residency, Internal Medicine, 2013Johns Hopkins University School of Medicine
Medical Education, MD, 2010Board Certifications
Rheumatology
American Board of Internal Medicine, 2016Internal Medicine
American Board of Internal Medicine, 2013Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Humana
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- UnitedHealthcare
- Veteran Affairs Community Care Network (Optum-VACCN)
Ratings & Reviews
5 out of 5
62 ratings, 28 reviewsThe Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
- 5 out of 5 starsReviewed on 2/19/2025
Doctor was very thorough and caring.
- 5 out of 5 starsReviewed on 2/19/2025
Dr Cappelli is an excellent provider, she is genuine and sympathetic yet firm and gentle
- 5 out of 5 starsReviewed on 2/5/2025
Dr. Cappelli is a delight. She's pleasant kind and explains everything well and in a way that is easy to understand. She offers options and genuinely shows care and concern.
- 5 out of 5 starsReviewed on 2/5/2025
Courteous and thorough
- 5 out of 5 starsReviewed on 1/29/2025
Dr Cappelli is outstanding! Her attention to detail, listening and showing her care for my well being is the best care I've received from any doctor. I come from York, PA because Dr. Cappelli is a great doctor.
- 5 out of 5 starsReviewed on 1/22/2025
Dr, Cappelli is a wonderful doctor and an asset to Hopkins. She is a pleasure to work with.
- 5 out of 5 starsReviewed on 1/22/2025
Dr. Cappelli has helped me thru difficult times. I trust her. She Is one of my best docs. She is always available for questions and adjustments and advice between visits. She is sympathetic, knowledgeable and empowered me to manage my conditoon.
- 5 out of 5 starsReviewed on 12/20/2024
So grateful I'm able to see Dr Cappelli. She's wonder.
- 5 out of 5 starsReviewed on 12/11/2024
The BEST rheumatologist I've ever had through many doctors in decades. Can't say enough wonderful things about her. Her knowledge of my numerous complex issues is always exactly right!! She truly listens and answer's every question and concern. I recommend and speak of her in such high regard through out almost two decades of being her patient. All students should learn how to treat their patients the way she does.She is so respectful, kind & compassionate to me. I have 100% faith in her over my health.
- 5 out of 5 starsReviewed on 11/20/2024
I've been seeing Dr Cappelli for the past 8 yrs and she has always been extremely attentive to my issues and answered all my questions about my condition and she has provided excellent care.
- 5 out of 5 starsReviewed on 11/20/2024
She is excellent and very knowledgable. Willing to work with the team of doctors to figure out my difficult diagnosis for the condition and numerous symptoms.
- 5 out of 5 starsReviewed on 11/6/2024
Dr Cappelli is wonderful. A very thorough doctor, caring, knowledgeable.
- 5 out of 5 starsReviewed on 10/23/2024
Always excellent, extremely professional, knowledgeable and caring.
- 5 out of 5 starsReviewed on 9/18/2024
Dr Cappelli is very knowledgeable and has a wonderful bedside manner. She is genuine and sincere.
- 5 out of 5 starsReviewed on 9/11/2024
Dr Laura Cappelli is excellent provider. She is very compassionate and she takes time to listen to your concerns and involves me in decision about my health care plan! I drive 7 hours to see this provider!
- 5 out of 5 starsReviewed on 9/4/2024
Dr. Capelli is very helpful and caring. She is a great doctor.
- 5 out of 5 starsReviewed on 8/28/2024
Dr. Capelli was thorough in her examination and discussed future treatment
- 5 out of 5 starsReviewed on 8/7/2024
Excellent feedback about alternatives
- 5 out of 5 starsReviewed on 7/31/2024
She listened to my concerns and actually heard what I was saying
- 5 out of 5 starsReviewed on 7/24/2024
She is great. A credit to Hopkins. Keep her
- 5 out of 5 starsReviewed on 7/3/2024
She is the best physician I have ever had. She is a brilliant creative scientist. These qualities are enhanced by her heartfelt empathy and connection to her patients. She is a rolemodel physician. I am privileged that she is my physician.
- 5 out of 5 starsReviewed on 6/19/2024
Dr Cappelli listened to my concerns and took it seriously by ordering follow up tests and helping me get into other specialists.
- 5 out of 5 starsReviewed on 5/29/2024
She is an excellent and very caring doctor
- 5 out of 5 starsReviewed on 5/15/2024
I am getting the care I expect
- 5 out of 5 starsReviewed on 5/15/2024
She has always been attentive when I ask questions, answers all of them. Dies a thorough exam of my joints and follows through when or if I have an issue with getting my medication.
- 5 out of 5 starsReviewed on 5/8/2024
Dr Cappelli is so compassionate, she takes time to give you the best care! I drive 4 hours to see her.
- 5 out of 5 starsReviewed on 5/1/2024
Dr. CAPPELLI is the best.
- 5 out of 5 starsReviewed on 3/27/2024
Dr Cappelli is very thorough in her exams and personable.