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Khaled Mahmoud El-Shami

Khaled Mahmoud El-Shami, MBCHB, MS, PhD

Leukemia

Lymphoma

Hematologic Malignancy

Accepting New Patients
5.0 of 5 stars230 ratings, 92 reviews

Highlights

Languages

  • Arabic
  • English

Gender

Male

Johns Hopkins Affiliations:

  • Johns Hopkins School of Medicine Faculty

About Khaled Mahmoud El-Shami

Primary Academic Title

Assistant Professor of Oncology

Background

Khaled M. El-Shami, M.B.Ch.B., Ph.D., is a medical oncologist at Johns Hopkins Kimmel Cancer Center at Sibley Memorial Hospital, as well as an assistant professor of oncology in the Division of Hematologic Malignancies at Johns Hopkins University School of Medicine.

Listen to Dr. El-Shami's Cancer Matters podcast episode to learn more about his work.

Dr. El-Shami's clinical interests are in hematologic malignancies, including leukemias, lymphomas and myelomas..

Dr. El-Shami graduated from Alexandria University Faculty of Medicine in Alexandria, Egypt, where he did a residency in the Department of Neurosurgery. He was a Chevening Scholar as a M.S. student in molecular genetics at the University of Sussex in the United Kingdom, as well as a Sam Cohen Windhoek Scholar as a Ph.D. student in cancer immunology at the Weizmann Institute in Israel. Dr. El-Shami also completed a residency in internal medicine at George Washington University School of Medicine, a fellowship in tumor immunology and biology at the National Cancer Institute, and a fellowship in medical oncology at Johns Hopkins University School of Medicine. Dr. El-Shami previously served as faculty at Georgetown University and George Washington University.

Dr. El-Shami has been named a Top Doctor by Washingtonian Magazine for several years.

Dr. El-Shami is a member of the American Association for Advancement of Science, the American Association of Cancer Research, the American Association of Immunologists, the American Society for Gene Therapy and the American Society of Clinical Oncology.

Dr. El-Shami's research focus is on hematologic malignancies, including acute and chronic leukemias, myelodysplastic syndromes, myeloprolifetive neplasms and lymphomas. He has received the National Institutes of Health Clinical Research Scholars Award, an American Medical Association Seed Grant and an American Society of Clinical Oncology Merit Award. 

Recent News Articles and Media Coverage

Research Interests

Lymphomas, Acute Leukemias, Chronic Leukemias, Drug Development in lymphoid Malignancies, Hematologic Malignancies.

Selected Publications

  • El-Shami, K., Oeffinger, K.C., Erb, N.L., Willis, A., Bretsch, J.K., Pratt-Chapman, M.L., Cannady, R.S., Wong, S.L., Rose, J., Barbour, A.L., Stein, K.D., Sharpe, K.B., Brooks, D.D., Cowens-Alvarado, R.L. "American Cancer Society Colorectal Cancer Survivorship Care Guidelines." CA Cancer J Clin. 2015 Nov-Dec;65(6):428-55. doi: 10.3322/caac.21286. Epub 2015 Sep 8. Review.

  • El-Shami, K., Stone, R.M., Smith, B.D. "FLT3 inhibitors in acute myeloid leukemia." Expert Rev Hematol. 2008 Dec;1(2):153-60. doi: 10.1586/17474086.1.2.153. Review.

  • Hossain, A., Rafei, H., Jariwala, A., El-Shami, K. "A rare breed: Wild-type braf and ighv expression in a 29 year old lady with classical hairy cell leukemia." Leuk Res Rep. 2017 Jan 24;7:20-22. doi: 10.1016/j.lrr.2017.01.001. eCollection 2017.

  • Parikh, S.A., Kantarjian, H., Schimmer, A., Walsh, W., Asatiani, E., El-Shami, K., Winton, E., Verstovsek, S. "Phase II study of obatoclax mesylate (GX15-070), a small-molecule BCL-2 family antagonist, for patients with myelofibrosis." Clin Lymphoma Myeloma Leuk. 2010 Aug;10(4):285-9. doi: 10.3816/CLML.2010.n.059.

  • Zheng, L., Edil, B.H., Soares, K.C., El-Shami, K., Uram, J.N., Judkins, C., Zhang, Z., Onners, B., Laheru, D., Pardoll, D., Jaffee, E.M., Schulick, R.D. "A safety and feasibility study of an allogeneic colon cancer cell vaccine administered with a granulocyte-macrophage colony stimulating factor-producing bystander cell line in patients with metastatic colorectal cancer." Ann Surg Oncol. 2014 Nov;21(12):3931-7. doi: 10.1245/s10434-014-3844-x. Epub 2014 Jun 19.

Honors

  • Top Doctor, Washingtonian Magazine
  • Merit Award, American Society of Clinical Oncology
  • Attending of the Year Award, George Washington University School of Medicine
  • Clinical Research Scholars Award, National Institutes of Health

Memberships

  • American Association for Advancement of Science,

    Member

  • American Association of Cancer Research,

    Member

  • American Association of Immunologists,

    Member

  • American Society for Gene Therapy,

    Member

  • American Society of Clinical Oncology,

    Member

Locations

  1. Sibley Memorial Hospital
    • 5255 Loughboro Road Northwest, Building B, Washington, DC 20016

    Expertise

    Education

    Johns Hopkins University School of Medicine

    Fellowship, Oncology, 2008

    The George Washington University School of Medicine

    Residency, Internal Medicine, 2005

    Weizmann Institute Weinberg Graduate School

    Graduate School, PhD, 2000

    University of Sussex

    Graduate School, BioChemistry, MS, 1993

    Alexandria University Hospital

    Residency, Surgery, 1992

    Alexandria University Faculty of Medicine

    Medical Education, MBChB MS, 1987

    Insurance

    Johns Hopkins providers accept various commercial health insurance plans. However, they may not be included in all of an insurance company's plans or offerings. This may include Exchange, Medicaid, Medicare, and specific limited benefit plans. Exceptions to participation also exist based on your employer’s benefits package and the provider's location or specialty. Please contact your insurer directly to make sure your doctor is covered by your plan. For more details, please review our Insurance Information.
    Search plans
    • Aetna
    • CareFirst
    • Cigna
    • First Health
    • Geisinger Health Plan
    • HealthSmart/Accel
    • Humana
    • Johns Hopkins Health Plans
    • MultiPlan
    • Pennsylvania's Preferred Health Networks (PPHN)
    • Point Comfort Underwriters
    • Private Healthcare Systems (PHCS)
    • UnitedHealthcare
    • Veteran Affairs Community Care Network (Optum-VACCN)

    Ratings & Reviews

    5 out of 5

    230 ratings, 92 reviews

    The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

    Overall Rating by Patient
    Average provider Overall Rating by Patient rating 4.9 out of 5 stars
    Provider Listened Carefully
    Average provider Provider Listened Carefully rating 5 out of 5 stars
    Provider Explained Things Clearly
    Average provider Provider Explained Things Clearly rating 5 out of 5 stars
    Provider Knew Medical History
    Average provider Provider Knew Medical History rating 5 out of 5 stars
    Provider Showed Respect
    Average provider Provider Showed Respect rating 5 out of 5 stars
    Provider Spent Enough Time
    Average provider Provider Spent Enough Time rating 5 out of 5 stars
    Search reviews
      5 out of 5 stars
      Reviewed on 3/19/2025

      Excellent

      5 out of 5 stars
      Reviewed on 2/17/2025

      Dr. El-Shami is the finest doctor I've ever been treated by.

      5 out of 5 stars
      Reviewed on 2/14/2025

      Dr. El-Shami is an outstanding specialist.I am very fortunate to be his patient.

      5 out of 5 stars
      Reviewed on 2/12/2025

      He is very knowledgeable and is able to translate his knowledge to my specific case

      5 out of 5 stars
      Reviewed on 2/10/2025

      I am very pleased with this doctor. He take his time to hear my concern and provides answer. An excellent doctor he does rush to get you out of his office.

      5 out of 5 stars
      Reviewed on 2/10/2025

      Dr El-Shami is kind, thoughtful, friendly, concerned and excellent.

      5 out of 5 stars
      Reviewed on 2/7/2025

      Excellent

      5 out of 5 stars
      Reviewed on 2/7/2025

      Dr. El-Shami Is a superb provider. I was impressed with his understanding of my current and former health history. He met my expectations and more, which were quite high for that visit. I felt he was open minded and tuned into some of my questions and concerns. He instilled a sense of confidence of guiding me firmly, but with consideration of who I am as a person.

      5 out of 5 stars
      Reviewed on 2/5/2025

      Excellent care

      5 out of 5 stars
      Reviewed on 2/3/2025

      Very,very good

      5 out of 5 stars
      Reviewed on 1/31/2025

      The best! Very knowledgeable and empathetic

      5 out of 5 stars
      Reviewed on 1/29/2025

      A very competent doctor.

      5 out of 5 stars
      Reviewed on 1/24/2025

      The medical oncology center at Sibley is just fantastic. So is Dr. El-Shami.

      5 out of 5 stars
      Reviewed on 1/15/2025

      Dr. El-Shami is the best! My life is in his hands and I trust him implicitly.

      5 out of 5 stars
      Reviewed on 1/15/2025

      Frienclly, helpful

      5 out of 5 stars
      Reviewed on 1/15/2025

      Dr El-Shami is excellent. He makes me feel very comfortable when discussing my health. 5 stars plus

      5 out of 5 stars
      Reviewed on 1/13/2025

      Dr. El-Shami is both brilliant and compassionate. I trust him implicitly with my care.

      5 out of 5 stars
      Reviewed on 1/10/2025

      I am confident re the care and advice provided to me by Dr. El-Shami.

      5 out of 5 stars
      Reviewed on 12/30/2024

      A+

      5 out of 5 stars
      Reviewed on 12/23/2024

      Good

      5 out of 5 stars
      Reviewed on 12/20/2024

      He's terrific: explains what the health issue is, how I am-health wise-, anything I should or shouldn't do. He is patient, helpful, and knowledgeable.

      5 out of 5 stars
      Reviewed on 12/20/2024

      I appreciate my provider El his patience and willing to listen

      5 out of 5 stars
      Reviewed on 12/16/2024

      Very knowledgeable and experienced and very friendly and caring about the patient.

      5 out of 5 stars
      Reviewed on 12/13/2024

      Dr is really excellent

      5 out of 5 stars
      Reviewed on 12/9/2024

      As long as I am benefiting from their service and they continue to be professional I will continue to use them

      5 out of 5 stars
      Reviewed on 12/6/2024

      Very trustworthy, kind, thorough

      5 out of 5 stars
      Reviewed on 12/6/2024

      There are no words to thank - [staff] and Dr. El-Shami For their expertise care and guidance through my journey of non-Hodgkin's lymphoma.

      5 out of 5 stars
      Reviewed on 12/2/2024

      Dr El-Shami helped me understand about my illness and made me feel very confident about the treatment.

      5 out of 5 stars
      Reviewed on 11/27/2024

      Extremely attentive to my somewhat unusual situation and plan of action to manage my cancer.

      5 out of 5 stars
      Reviewed on 11/22/2024

      Exceptional compassion, warmth & care.

      5 out of 5 stars
      Reviewed on 11/18/2024

      Dr. El-Shami always makes sure I understand exactly what he says.

      5 out of 5 stars
      Reviewed on 11/14/2024

      Dr El-Shami asked, listened and showed care about my current situation.

      5 out of 5 stars
      Reviewed on 11/13/2024

      Dr. El-Shami is an excellent doctor. Not only is he very knowledgeable, he also has a awesome bedside manner. He is very thoughtful, kind and concerned about me having the best of care.

      5 out of 5 stars
      Reviewed on 11/8/2024

      Dr. El Shami is an excellent and caring physician.

      5 out of 5 stars
      Reviewed on 11/6/2024

      Amazing Dr. El- Shami!!!

      5 out of 5 stars
      Reviewed on 11/4/2024

      Dr. El-Shami is unformly excellent in his care and attention to my medical issues.

      5 out of 5 stars
      Reviewed on 11/1/2024

      Always very informative and supportive related to my condition and related test results

      5 out of 5 stars
      Reviewed on 11/1/2024

      Dr. El-Shami is the best. He saved my life.

      5 out of 5 stars
      Reviewed on 10/28/2024

      Dr el-shami is a treasure. A fantastic doctor and a great person.

      5 out of 5 stars
      Reviewed on 10/28/2024

      Very courteous and understanding

      5 out of 5 stars
      Reviewed on 10/25/2024

      Dr. El-Shami is an excellent Dr. With a tremendous knowledge in his field.

      5 out of 5 stars
      Reviewed on 10/25/2024

      Outstanding

      5 out of 5 stars
      Reviewed on 10/25/2024

      Dr El Shami is kind, listens attentively, makes excellent eye contact, thoughtful and reassuring.

      5 out of 5 stars
      Reviewed on 10/2/2024

      Excellent

      5 out of 5 stars
      Reviewed on 10/2/2024

      Very knowledgeable and was easy to communicate with

      5 out of 5 stars
      Reviewed on 9/30/2024

      Great

      5 out of 5 stars
      Reviewed on 9/25/2024

      Dr. El-Shami is the best

      5 out of 5 stars
      Reviewed on 9/18/2024

      During my ongoing period of care via Dr. El Shami, I feel confident that I have received good care.

      5 out of 5 stars
      Reviewed on 9/16/2024

      Superb physician an excellent clinician & a very humane wonderful person the best I have ever met in my life.

      5 out of 5 stars
      Reviewed on 9/16/2024

      He was very understanding and informative about my condition. He made me feel that I was in good hands.

      5 out of 5 stars
      Reviewed on 9/11/2024

      Super doc who listens

      5 out of 5 stars
      Reviewed on 9/9/2024

      Outstanding. He cares and is very interested in.my continued recovery from the lymphoma he treated me for.

      5 out of 5 stars
      Reviewed on 9/9/2024

      Dr ElShami is outstanding, very kind and makes me feel safe

      5 out of 5 stars
      Reviewed on 8/30/2024

      Excellent and knowledgeable professional. Answered all questions precisely. Totally explained my situation and procedure going forward

      5 out of 5 stars
      Reviewed on 8/28/2024

      Dr El Shami has been caring for me for 10 years and is absolutely the best

      5 out of 5 stars
      Reviewed on 8/26/2024

      Dr El-Shami has always listened to my concerns and has answered them to my satisfaction and understanding

      5 out of 5 stars
      Reviewed on 8/26/2024

      Very good support

      5 out of 5 stars
      Reviewed on 8/19/2024

      Dr El-Shami is a #1 physician, caring, listening, providing information.

      5 out of 5 stars
      Reviewed on 8/16/2024

      Excellent provider

      5 out of 5 stars
      Reviewed on 8/16/2024

      He's great; knowledgeable, patient, understanding, thorough.

      5 out of 5 stars
      Reviewed on 8/9/2024

      Dr. El-Shami is very knowledgeable and caring. He takes all the time required to listen and answer any questions.

      5 out of 5 stars
      Reviewed on 7/29/2024

      Extremely knowledgeable and caring. Saved my life--probably twice!

      5 out of 5 stars
      Reviewed on 7/22/2024

      Dr. El Shami displayed a thorough understanding of my condition, provided in depth explanations of the treatment options, and helped me make a we informed decision. He presents as knowledgeable, compassionate, caring and unhurried. I would definitely seek his advice again and would wholeheartedly recommend him.

      5 out of 5 stars
      Reviewed on 7/19/2024

      Provider allowed us time to discuss [Patient] results and further treatment

      5 out of 5 stars
      Reviewed on 7/17/2024

      Dr. El-Shami has been fabulous. I feel like I am getting the best possible care for my condition.

      5 out of 5 stars
      Reviewed on 7/17/2024

      Thorough, knowledgeable, conscientious, polite and caring. I am fortunate to have him caring for me

      5 out of 5 stars
      Reviewed on 6/28/2024

      EXCELLENT!

      5 out of 5 stars
      Reviewed on 6/26/2024

      Consistently excellent care

      5 out of 5 stars
      Reviewed on 6/26/2024

      Dr. El Shami is the best doctor I have ever had and I've had many.

      5 out of 5 stars
      Reviewed on 6/26/2024

      Dr El Shami is always attentive and professional. He spends time explaining test results and therapies. I feel like I'm in good hands.

      5 out of 5 stars
      Reviewed on 6/26/2024

      Dr El-Shami is extremely smart and focused on his patient.

      5 out of 5 stars
      Reviewed on 6/24/2024

      Excellent. Could not be bettrer.

      5 out of 5 stars
      Reviewed on 6/7/2024

      Terrific Dr.

      5 out of 5 stars
      Reviewed on 5/29/2024

      Doctor El-Shami was great, in terms of being very professional and knew the reason I was there. He clearly explained everything to me and made sure I understood.

      5 out of 5 stars
      Reviewed on 5/24/2024

      Highly pleased

      5 out of 5 stars
      Reviewed on 5/24/2024

      I'm thankful to God Almighty for the doctor El Sharmi is very understanding and very patient and he sit and talk to me and treated me with respect and making sure that I understood what he was telling me about my health I'm grateful

      5 out of 5 stars
      Reviewed on 5/22/2024

      Dr El-Shami is the best!!!!!

      5 out of 5 stars
      Reviewed on 5/21/2024

      Very knowledgeable about my disease and condition. Excellent about reviewing my overall health.

      5 out of 5 stars
      Reviewed on 5/20/2024

      Dr. Elshami is professional, compassionate, knowledgeable, and effectively saved my life recommending Car tea therapy

      5 out of 5 stars
      Reviewed on 5/15/2024

      He is very attentive and compassionate. I felt that he had put in the time familiarizing himself with my medical history before our appointment.

      5 out of 5 stars
      Reviewed on 5/15/2024

      Dr. El-Shami is the most professional, warn, compassionate & caring doctor. He listens & makes me feel very comfortable & confident with my treatments.

      5 out of 5 stars
      Reviewed on 5/15/2024

      Dr. El-Shami is great. He explains every issue that comes up in understandable detail. He took the time to explain something that is tangential to the condition I see him about, as well as details of other medical issues with which I deal.

      5 out of 5 stars
      Reviewed on 5/15/2024

      Compassionate caring and informative Dr. He sees my mind at ease and takes time to explain everything

      5 out of 5 stars
      Reviewed on 5/10/2024

      Doctor Khalid El- Shami

      5 out of 5 stars
      Reviewed on 5/8/2024

      He's the best oncologist in DC! He's keeping me alive! I'd follow him anywhere!

      5 out of 5 stars
      Reviewed on 5/8/2024

      Great working with Dr. El Shami

      5 out of 5 stars
      Reviewed on 4/23/2024

      The doctor has been has been diligent in my healing process. I feel as though he genuinely cares about my health in getting rid of this cancer.

      5 out of 5 stars
      Reviewed on 4/22/2024

      It was actually my first visit with Dr. El-Shahimi, though I've seen other providers in this office for several years. He was truly excellent.

      5 out of 5 stars
      Reviewed on 4/19/2024

      Dr El-Shami is in absolutely the best Dr. Very much the expert with a great bedside manner.

      5 out of 5 stars
      Reviewed on 4/16/2024

      Superb ! Excellent! Compassionate & Caring one of the very BEST physicians I have ever encountered in my own life as a physician of 37 years experience .

      5 out of 5 stars
      Reviewed on 4/3/2024

      Dr. El Shami is excellent, kind, careful, caring and explains clearly what's going on and how to handle it

      5 out of 5 stars
      Reviewed on 4/2/2024

      Very good