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Jon Ling

Jon Ling, PhD

Highlights

Languages

  • English

Gender

Male

Johns Hopkins Affiliations:

  • Johns Hopkins School of Medicine Faculty

About Jon Ling

Primary Academic Title

Assistant Professor of Pathology

Background

Dr. Ling is an Assistant Professor of Pathology at The Johns Hopkins School of Medicine. His research combines bioinformatics and genetic engineering to develop therapeutic strategies for age-related neurodegenerative diseases and monogenic disorders. He employs large-scale computational analyses of next-generation sequencing data to identify novel disease mechanisms, with the goal of translating these discoveries to the clinic.

Dr. Ling received his undergraduate degree from Johns Hopkins University. He earned his Ph.D. from The Johns Hopkins School of Medicine and completed his postdoctoral fellowship at the JHU Kavli Neuroscience Discovery Institute. Dr. Ling joined the Johns Hopkins faculty in 2020.

Selected Publications

  • *Jeong YH, *Ling JP, *Lin SZ, Donde AN, Braunstein KE, Majounie E, Traynor BJ, LaClair KD, Lloyd TE, Wong PC. Tdp-43 cryptic exons are highly variable between cell types. Mol Neurodegener. 2017 Feb 2;12(1):13. PMCID: PMC5289002. 

  • Ling JP, Chhabra R, Merran JD, Schaughency PM, Wheelan SJ, Corden JL, Wong PC. PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons. Cell Rep. 2016 Sep 27;17(1):104–13. PMCID: PMC5082185

  • Ling JP, Pletnikova O, Troncoso JC, Wong PC. TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD. Science. 2015 Aug 7;349(6248):650-5. PMCID: PMC4825810

  • Ling JP, Wilks C, Charles R, Leavey PJ, Ghosh D, Jiang L, Santiago CP, Pang B, Venkataraman A, Clark BS, Nellore A, Langmead B, Blackshaw S. ASCOT identifies key regulators of neuronal subtype-specific splicing. Nat Commun. 2020 Jan 9;11(1):137

  • McClory SP, Lynch KW, Ling JP. HnRNP L represses cryptic exons. RNA. 2018 Jun;24(6):761-768. PMID: 29581412

Honors

  • Kavli NDI Postdoctoral Fellowship, 1/1/17
  • Mette Strand Award, Johns Hopkins University School of Medicine, 1/1/16

Memberships

  • Society for Neuroscience
  • Association for Research in Vision and Ophthalmology
  • RNA Society

Expertise

Education

Johns Hopkins University School of Medicine

Ph.D., 2017

Johns Hopkins University

B.S., 2010