Jeff W. Bulte, MS, PhD
Highlights
Languages
- English
Gender
MaleJohns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Jeff W. Bulte
Professional Titles
- Director of Cellular Imaging, The Johns Hopkins Institute for Cell Engineering
- Inaugural Director of Scientific Communications, Department of Radiology
Primary Academic Title
Professor of Radiology and Radiological Science
Background
Dr. Jeff W. M. Bulte is a Professor in the Johns Hopkins Departments of Radiology, Oncology, Biomedical Engineering, and Chemical & Biomolecular Engineering. He serves as the Inaugural Director of Scientific Communications in the Department of Radiology, and is Director of Cellular Imaging at the Johns Hopkins Institute for Cell Engineering. He specializes in molecular and cellular imaging.
Dr. Bulte has pioneered methods to label cells magnetically, making them visible by magnetic resonance imaging (MRI) and magnetic particle imaging (MPI). His team is developing in vivo cell tracking techniques, reporter genes and immunoprotective semi-permeable microcapsules detectable by MRI, MPI, computed tomography, ultrasound, and bioluminescent imaging.
Dr. Bulte received his undergraduate degree in biology and a master's in medical biology from the Free University of Amsterdam in The Netherlands. He earned his Ph.D. in medicine summa cum laude from the University of Groningen in the Netherlands in 1991. He subsequently spent 10 years with the National Institutes of Health, first as a postdoctoral fellow and then a staff scientist in the Laboratory of Diagnostic Radiology Research. Dr. Bulte joined the Johns Hopkins faculty as an Assistant Professor in 2001, became an Associate Professor in 2002, and a Professor in 2006.
He is a Fellow and Gold Medal awardee of the International Society of Magnetic Resonance in Medicine, a Fellow of the World Molecular Imaging Society, a Fellow of the American Institute of Medical BioEngineering, and a Distinguished Investigator of the Academy of Radiology Research. He has published over 300 peer-reviewed articles and 50 book chapters, and serves on the editorial boards of Radiology, WIREs Nanomedicine and Nanobiotechnology, Molecular Imaging, the Journal of Magnetic Resonance Imaging, and Tomography.
Centers and Institutes
Clinical Trial Keywords
Breast cancer, radiation-induced fibrosis, stem cells, dendritic cells, immunotherapy, cancer vaccination
Clinical Trials Summary
19F Hot Spot MRI of Human Adipose-derived Stem Cells for Breast Reconstruction (CS-1000)
Videos
Recent News Articles and Media Coverage
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Mouse Experiments Show How Sugar Molecules Can Be Used to Track Stem Cells, Johns Hopkins Medicine (February 7, 2022)
Ranked #4 world-wide as expert in molecular imaging, Expertscape (2021)
Magnetic Insight installs new HYPER localized magnetic theranostic system at Johns Hopkins University, Magnetic Insight (August 11, 2021)
New Magnetic Particle Imager Offers New Opportunities in Molecular and Cellular Imaging Research, Johns Hopkins Institute for NanoBioTechnology (June 29, 2021)
New Momentum Magnetic Particle Imaging Scanner to be installed in Baltimore, PR Newswire (August 29, 2019)
Additional Academic Titles
Professor of Biomedical Engineering, Professor of Oncology
Contact for Research Inquiries
Johns Hopkins Institute for Cell Engineering
733 N. Broadway
MRB 659
Baltimore, MD 21205-2109
jwmbulte@mri.jhu.edu
Research Interests
CEST, Contrast Agents, Molecular and Cellular Imaging, MPI, MRI, Nanoparticles, Reporter Genes, Stem Cells, Theranostics
Lab Website
Jeff Bulte Lab
The Bulte Lab has developed methods to label cells magnetically using tiny superparamagnetic iron oxide nanoparticles in order to make them visible by magnetic resonance imaging; this technology has now been introduced in the clinic for several cell therapy applications. The lab has examined MRI cell tracking in animal models of dysmyelination, multiple sclerosis, brain tumors, spinal cord, stroke, and diabetes.
Research Summary
New contrast agent and theranostics development as applied to molecular and cellular imaging, with particular emphasis on in vivo cell tracking.
Honors
- Fellow, American Institute for Medical Bioengineering, 1/1/21
- Fellow, World Molecular Imaging Society, 9/5/19
- Thorsten Almen Award for Pioneering Research in Contrast Media Research, CMR, 9/9/15
- Gold Medal, International Society for Magnetic Resonance, 5/12/14
- Distinguished Investigator, Academy of Radiology Research, 9/16/12
- EUREKA Award, NIH, 7/1/08
- Fellow, International Society for Magnetic Resonance in Medicine, 5/5/08
- Semi-Finalist, HHMI Investigator Tri-Annual Open Competition, 1/25/08
- PhD "Summa Cum Laude", 12/18/91
Graduate Program Affiliations
Additional Training
- Postdoctoral Fellow, Laboratory of Diagnostic Radiology Research (NIH), 1992-1995