
Jim C. Fackler, MD
Pediatric Anesthesiology
Pediatric Critical Care Medicine
- Johns Hopkins School of Medicine Faculty
About Jim C. Fackler
Primary Academic Title
Professor of Anesthesiology and Critical Care Medicine
Background
Dr. James Fackler is a professor of anesthesiology and critical care medicine at the Johns Hopkins University School of Medicine. His areas of clinical expertise include acute respiratory distress syndrome, novel respiratory therapies, and critical care informatics.
Dr. Fackler received his undergraduate degree in biology from the University of Illinois and earned his M.D. from Rush Medical College in Chicago. He completed his residencies in pediatrics and anesthesiology and then fellowships in pediatric intensive care and pediatric anesthesia at the Johns Hopkins University School of Medicine. His first faculty position was at the Children's Hospital in Boston where he was an early leader in use of the internet for health data exchange and critical care monitoring.
Dr. Fackler returned to the Johns Hopkins faculty in 1996 to run the Extracorporeal Membrane Oxygenation program and Respiratory Therapy.
He took a "sabbatical" from 2002 to 2006 and worked for the Cerner Corporation developing their critical care and device integration solutions. He has founded three health care informatics-based startups and consults for other device and information integration companies.
Dr. Fackler's research interests include optimizing team performance in pediatric critical care. He has mentored pediatric residents, critical care fellows, and biomedical engineering undergrads, Masters and PhD students. His current major focus is on sepsis.
He serves as an associate editor for Pediatric Critical Care Medicine and as an ad hoc journal reviewer for many notable publications including New England Journal of Medicine and Critical Care Medicine. He is a member of American Association of Artificial Intelligence, American Medical Informatics Association and the Society for Critical Care Medicine. He helped found, and is on the Board of the non-profit, Machine Learning for Healthcare.
Dr. Fackler is a frequent lecturer and panelist on the subject of critical care informatics. He is an expert in data integration and its use.
Centers and Institutes
Research Interests
Machine and Reinforcement Learning in Critical Care, Team Performance Optimization
Lab Website
James Fackler Lab - Lab Website
Research Summary
Dr. Fackler is interested in data acquisition and data mining in the operating room and intensive care unit. In the ICU, each patient has 300–350 associated data elements. Blood pressure, heart rate, potassium concentration and hemoglobin level are just a few examples. Studies have shown that the human brain can comprehend seven individual parcels of data at once. If the data can be sorted into patterns, an individual may be able to manage seven individual patterns. Dr. Fackler hopes to identify patterns among the patient data and establish recognizable trends that occur over time. The understanding of such patterns and trends could help clinical professionals to make more educated, evidence-based decisions on patient care.
Selected Publications
Liu R, Greenstein JL, Fackler JC, Bergmann J, Bembea MM, Winslow RL. Prediction of impending septic shock in children with sepsis. Crit Care Explor. 2021 Jun 15;3(6):e0442.
Liu R, Greenstein JL, Granite SJ, Fackler JC, Bembea MM, Sarma SV, Winslow RL. Data-driven discovery of a novel sepsis pre-shock state predicts impending septic shock in the ICU. Sci Rep 2019;9(1):6145.
Liu R, Greenstein JL, Granite SJ, Fackler JC, Bembea MM, Sarma SV, Winslow RL. Spectral Clustering of Risk Score Trajectories Stratifies Sepsis Patients by Clinical Outcome and Interventions Received. eLife. 2020;9:e58142 DOI: 10.7554/eLife.58142
Woods-Hill C, Fackler J*, Nelson McMillan K, Ascenzi J, Martinez D, Toerper M, Voskertchian A, Colantuoni E, Klaus S, Levin S, Aaron Milstone. Association of a clinical practice guideline with blood culture use in critically ill children. JAMA Pediatr. 2017;171(2):157-64.
Woods-Hill CZ, Koontz DW, Voskertchian A, Xie A, Shay J, Miller MR, Fackler JC, Milstone AM, and the BrightStar Authorship group. Consensus recommendations for blood culture use in critically ill children: a modified Delphi approach. Pediatr Crit Care Med. 2021 Sep 1;v22(9):774-784. doi: 10.1097/PCC.0000000000002749. PMID: 33899804; PMCID: PMC8416691.
Honors
Alpha Omega Alpha, Rush Medical College, 1/1/79
Memberships
- American Academy of Pediatrics
- American Association of Artificial Intelligence
- American Medical Association
- American Medical Informatics Association
- American Society of Anesthesiologists
- American Telemedicine Association
- American Thoracic Society
- Association of University Anesthesiologists
- Committee on Information Technologies, Member
- Electronic Communication Committee
- Extracorporeal Life Support Organization
- Industry Partner, Coalition for Critical Care Excellence
- Massachusetts Medical Society
- Massachusetts Society of Anesthesiologists
- Member Steering Committee
- Society for Critical Care Medicine
- Suffolk District Medical Society
Professional Activities
- Cardiopulmonary Corp, Founder, 1/1/09
- Chest, Ad hoc reviewer
- Critical Care Medicine, Ad hoc reviewer
- Electronic Communication Committee, Vice Chairman, 1/1/01 - 1/1/02
- Electronic Communication Committee, Vice Chairman, 1/1/00 - 1/1/01
- House of Delegates, Delegate, 1/1/94 - 1/1/95
- Intensive Care Medicine, Ad hoc reviewer
- International Journal of Medical Informatics, Ad hoc reviewer
- New England Journal of Medicine, Ad hoc reviewer
- Oak Clinical Informatics Systems, 1/1/08
- Pediatric Critical Care Medicine, Editor, 1/1/01
- Protocols Committee, Chairman, 1/1/94 - 1/1/97
- Transactions on Modeling and Computer Simulation, Ad hoc reviewer
Locations
- The Johns Hopkins Hospital
- 1800 Orleans Street, Baltimore, MD 21287
- phone: 410-955-5000
- fax: 410-955-5001
Expertise
Education
Johns Hopkins University School of Medicine
Residency, Anesthesiology, 1986Johns Hopkins University School of Medicine
Residency, Pediatrics, 1983Rush Medical College
Medical Education, MD, 1980Board Certifications
Pediatric Critical Care Medicine
American Board of Pediatrics, 1992Anesthesiology
American Board of Anesthesiology, 1991Pediatrics
American Board of Pediatrics, 1986Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Humana
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- UnitedHealthcare
- Veteran Affairs Community Care Network (Optum-VACCN)