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Elena MacFarlane

Elena MacFarlane, PhD

Johns Hopkins Affiliations:
  • Johns Hopkins School of Medicine Faculty

Languages

  • English

Gender

Female

About Elena MacFarlane

Primary Academic Title

Assistant Professor of Genetic Medicine

Background

Dr. Elena Gallo MacFarlane is an Assistant Professor in the McKusick-Nathans Institute of Genetic Medicine. She studies the genetic, epigenetic and biochemical mechanisms that account for susceptibility to signaling perturbations in vascular disease, with particular focus on hereditary forms of aneurysm.

She received a bachelor’s degree from the University of Milan, Italy and a PhD from Stanford University School of Medicine before joining the faculty. She is a member of the American Society for Human Genetics, the American Heart Association and the North American Vascular Biology Organization.

Additional Academic Titles

Assistant Professor of Surgery

Contact for Research Inquiries

733 N. Broadway
Miller Research Building
Baltimore, MD 21205

Phone: (410) 955-4134

Selected Publications

  • Gallo EM, Loch DC, Habashi JP, Calderon JF, Chen Y, Bedja D, van Erp C, Gerber EE, Parker SJ, Sauls K, Judge DP, Cooke SK, Lindsay ME, Rouf R, Myers L, ap Rhys CM, Kent KC, Norris RA, Huso DL and Dietz HC. (2014). Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. J Clinical Investigation, 124(1): 448-460

  • Gallo MacFarlane E, Haupt J, Dietz HC, Shore E (2017). TGF-beta Family Signaling in Connective Tissue and Skeletal Diseases. Cold Spring Harb Perspect Biol. 2017 Nov 1;9(11); a022269.

  • Gallo MacFarlane E, Parker SJ, Shin JY, Ziegler SG, Creamer TJ, Bagirzadeh R, Bedja D, Chen Y, Calderon SF, Weissler K., Guerrerio PA, Lindsay ME, Habashi JP and Dietz HC. (2019) Lineage-specific events underlie aortic root aneurysm pathogenesis in Loeys-Dietz syndrome”. The Journal of Clinical Investigation, Epub 2019/01/08

Expertise

Education

Stanford University School of Medicine

Ph.D., 2008

University of Milan

B.S., 2002