Elena MacFarlane, PhD
- Johns Hopkins School of Medicine Faculty
Languages
- English
Gender
FemaleAbout Elena MacFarlane
Primary Academic Title
Assistant Professor of Genetic Medicine
Background
Dr. Elena Gallo MacFarlane is an Assistant Professor in the McKusick-Nathans Institute of Genetic Medicine. She studies the genetic, epigenetic and biochemical mechanisms that account for susceptibility to signaling perturbations in vascular disease, with particular focus on hereditary forms of aneurysm.
She received a bachelor’s degree from the University of Milan, Italy and a PhD from Stanford University School of Medicine before joining the faculty. She is a member of the American Society for Human Genetics, the American Heart Association and the North American Vascular Biology Organization.
Additional Academic Titles
Assistant Professor of Surgery
Contact for Research Inquiries
733 N. Broadway
Miller Research Building
Baltimore, MD 21205
Phone: (410) 955-4134
Selected Publications
Gallo EM, Loch DC, Habashi JP, Calderon JF, Chen Y, Bedja D, van Erp C, Gerber EE, Parker SJ, Sauls K, Judge DP, Cooke SK, Lindsay ME, Rouf R, Myers L, ap Rhys CM, Kent KC, Norris RA, Huso DL and Dietz HC. (2014). Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. J Clinical Investigation, 124(1): 448-460
Gallo MacFarlane E, Haupt J, Dietz HC, Shore E (2017). TGF-beta Family Signaling in Connective Tissue and Skeletal Diseases. Cold Spring Harb Perspect Biol. 2017 Nov 1;9(11); a022269.
Gallo MacFarlane E, Parker SJ, Shin JY, Ziegler SG, Creamer TJ, Bagirzadeh R, Bedja D, Chen Y, Calderon SF, Weissler K., Guerrerio PA, Lindsay ME, Habashi JP and Dietz HC. (2019) Lineage-specific events underlie aortic root aneurysm pathogenesis in Loeys-Dietz syndrome”. The Journal of Clinical Investigation, Epub 2019/01/08