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David McConkey

David McConkey, PhD

Johns Hopkins Affiliations:
  • Johns Hopkins School of Medicine Faculty

Languages

  • English

Gender

Male

About David McConkey

Professional Titles

  • Director, Johns Hopkins Greenberg Bladder Cancer Institute

Primary Academic Title

Professor of Urology

Background

David J. McConkey, Ph.D., is the inaugural director of the Johns Hopkins Greenberg Bladder Cancer Institute and professor in the Department of Urology at Johns Hopkins Medicine. His mission is to make the Institute a hub of an institutional and international community of researchers who share a commitment to advancing the scientific understanding of bladder cancer and improving its treatment.

Additional Academic Titles

Professor of Oncology

Selected Publications

  • McConkey DJ, Choi W, Shen Y, Lee IL, Porten S, Matin SF, Kamat AM, Corn P, Milikan RE, Dinney C, Czerniak B, Siefker-Radtke AO. A prognostic gene expression signature in the molecular classification of chemotherapy-naïve urothelial cancer is predictive of clinical outcomes from neoadjuvant chemotherapy: A phase 2 trial of dose-dense methotrexate, vinblastine, doxorubicin, and cisplatin with bevacizumab in urothelial cancer. Eur Urol. 2016:69(5):855-62. PMCID: PMC4775435

  • Choi W, Porten S, Kim SH, Roth B, Cheng T, Willis D, Tran MN, Lee IL, Melquist J, Bondaruk JE, McConkey DJ. Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy. Cancer Cell. 2014:25(2):152-65. PMCID: PMC4011497

  • Guo CC, Dadhania V, Zhang L, Majewski , Bondaruk J, Sykulski M, Wronowska W, Gambin A, Wang Y, Zhang S, Fuentes-Mattei E, Kamat AM, Dinney C, Siefker-Radtke A, Choi W, Baggerly KA, McConkey D, Weinstein JN, Czerniak B. Gene expression profile of the clinically aggressive micropapillary variant of bladder cancer.  Eur. Urol. 2016. e-Pub ahead of print. PMID: 26988609

  • Plimack ER, Dunbrack RL, Brennan TA, Andrake MD, Zhou Y, McConkey DJ, Miller VA, et al. Defects in DNA repair genes predict response to neoadjuvant cisplatin-based chemotherapy in muscle-invasiv bladder cancer. Eur Urol. 2015:68(6):959-67. e-Pub ahead of print. PMCID: PMC4764095

  • The Cancer Genome Atlas research network contributed collectively to this study: Weinstein JN, Akbani R, Broom BM, Wang W, …McConkey DJ…. Comprehensive molecular characterization of urothelial carcinoma of the bladder. Nature. 2014:507(7492):315-22. PMCID: PMC3962515.

Honors

  • Sowell-Huggins Professor and Fellow in Cancer Research, 1/1/16
  • Robert F. Fly Professorship of Surgical Oncology, 1/1/14
  • Reappointed to GSBS Faculty with Highest Commendation, 1/1/13
  • Award for Research Excellence, UT M.D. Anderson Cancer Center, 1/1/03
  • Finalist, Julie and Ben Rogers Award for Excellence, 1/1/03
  • Educator of the Month, M. D. Anderson Cancer Center, 1/1/02
  • HSC Honors Convocation Recipient, 1/1/01
  • John P. McGowen Outstanding Teacher Award, University of Texas Health Science Center, GSBS, 1/1/01
  • Cancer Research Institute Fellowship, 1/1/91
  • American Scandinavian Foundation Fellowship, 1/1/86

Memberships

  • American Association for Cancer Research
  • Gulf Coast Society of Toxicology
  • Society of Toxicology
  • American Association of Immunologists
  • American Society of Hematology
  • American Urological Society
  • Society of Basic Urological Research, Houston, TX
  • Society of Urologic Oncology
  • American Society of Clinical Oncology Member

Professional Activities

  • Conflict of Interest Committee, Member., 1/1/01 - 1/1/05
  • Department of Urology Chairman Search Committee, Member, 1/1/03 - 1/1/04
  • Executive Committee of the Faculty Senate, Member, 1/1/00 - 1/1/03
  • Executive Committee of the Science Faculty, Member, 1/1/08 - 1/30/08
  • Executive Committee, Bladder Cancer SPORE, Member, 1/1/01
  • Executive Committee, Pancreatic Cancer SPORE, Member, 1/1/04 - 1/1/08
  • Experimental Therapeutics Advisory Committee, Member, 1/1/00 - 1/1/03
  • Faculty Senate, Member, 1/1/99 - 1/1/04
  • Institutional Research Executive Committee, Member, 1/1/12 - 1/1/14
  • Internal Advisory Committee, AML P01 (PI: Andreeff),, Member, 1/1/99
  • Internal Advisory Committee, Lymphoma SPORE (PI: Younes), Member, 1/1/08 - 1/30/08
  • Postdoctoral Advisory Committee, Member, 1/1/08 - 1/30/08
  • Research Laboratory Space Subcommittee, Member, 1/1/02 - 1/1/05
  • UTMDACC CTDP Study Section, Member, 1/1/01

Expertise

Education

Karolinska Institutet

Ph.D., 1989

Brown University

B.A., 1986