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Arvind Pathak

Arvind Pathak, PhD

Johns Hopkins Affiliations:
  • Johns Hopkins School of Medicine Faculty

Languages

  • English

Gender

Male

About Arvind Pathak

Primary Academic Title

Professor of Radiology and Radiological Science

Background

Dr. Pathak is Professor of Radiology, Oncology, Biomedical Engineering and Electrical Engineering at Johns Hopkins University (JHU). He is a member of the Sidney Kimmel Comprehensive Cancer Center, the Institute for NanoBioTechnology (INBT), the Institute for Computational Medicine (ICM), and the Translational Tissue Engineering Center (TTEC). He directs the Image-based Systems Biology Laboratory whose mission is to “transform lives via power of images”.

Dr. Pathak received his BS in Electronics Engineering from the University of Poona, India. He then received his PhD from the joint program in Functional Imaging between the Medical College of Wisconsin and Marquette University, where he was a Whitaker Foundation Fellow. He completed a postdoctoral fellowship in Molecular Imaging in the Dept. of Radiology at the Johns Hopkins University School of Medicine. He is a globally recognized expert on functional and molecular imaging, and his high-impact research has been recognized by multiple awards such as the Bill Negendank Award from the International Society for Magnetic Resonance in Medicine (ISMRM), and the Career Catalyst Award from the Susan Komen Breast Cancer Foundation, to name a few.

Dr. Pathak has served in multiple leadership roles spearheading imaging initiatives, review panels for national and international funding agencies, and journal editorial boards. He has mentored over a 100 award-winning students, staff and junior faculty. He has served on multiple diversity initiatives and is dedicated to mentoring the next generation of thought leaders in imaging. He was the recipient of the ISMRM’s Outstanding Teacher Award and recognized as a 125 Hopkins Hero by the JHU School of Medicine for his “outstanding dedication to the educational and research values of Johns Hopkins University”.

Recent News Articles and Media Coverage

  • Mini Microscope is the New GoPro for Studies of Brain Disease in Living Mice, Johns Hopkins Medicine News Releases (03/27/2019)

    ‘Google Maps’ for Cancer: Image-Based Computer Model Reveals Finer Details of Tumor Blood Flow Behavior, Johns Hopkins Medicine News Releases (05/06/2019)

    New contrast agent combination could usher in a new era of vascular systems biology, Phys.org (September 16, 2019)

    Scientists Develop Free Computer Program to Map Blood Flow ‘Landscape’ in Tumors, Johns Hopkins Medicine (March 05, 2020)

    Making the Invisible Visible: A Clearer ‘Picture’ of Blood Vessels in Health and Disease Thanks to New Imaging Approach, Johns Hopkins Medicine (February 28, 2022

Additional Academic Titles

Professor of Biomedical Engineering, Professor of Oncology

Research Interests

 Functional & Molecular Imaging, Image-based Biomarkers for Precision Medicine, Image-based Systems Biology,  Neuroimaging, Image-informed Tissue Engineering.

Lab Website

Pathak Laboratory - Lab Website

  • The Pathak Lab is an interdisciplinary program that works at the intersection of engineering, medicine, and design to develop new hardware, software, and 'wetware' tools that provide insights into disease, enable biomarker discovery, and impact health and society.

Research Summary

The Pathak Lab is an interdisciplinary research and educational program at the intersection of engineering, medicine and design develops new hardware, software and tools for gaining insights into disease, enabling biomarker discovery, and impacting health and society. Our goal is to transform lives via the power of imaging. Our interdisciplinary research encompasses the following areas: 1. Functional & Molecular Imaging; 2. Biomarkers for Precision Medicine; 3. Image-based Systems Biology; 4. Neuroimaging; 5. Image-informed Tissue Engineering.

Selected Publications

  • Bhargava A, Monteagudo B, Kushwaha P, Senarathna J, Ren Y, Riddle RC, Aggarwal M, Pathak AP. VascuViz: a multimodality and multiscale imaging and visualization pipeline for vascular systems biology. Nat Methods. 2022 Feb;19(2):242-254. doi: 10.1038/s41592-021-01363-5. Epub 2022 Feb 10. PMID: 35145319; PMCID: PMC8842955

  • Bhargava A, Popel AS, Pathak AP. Vascular phenotyping of the invasive front in breast cancer using a 3D angiogenesis atlas. Microvasc Res. 2023 May 29;149:104555. doi: 10.1016/j.mvr.2023.104555. Epub ahead of print. PMID: 37257688

  • Ren Y, Senarathna J, Grayson WL, Pathak AP. State-of-the-art techniques for imaging the vascular microenvironment in craniofacial bone tissue engineering applications. Am J Physiol Cell Physiol. 2022 Nov 1;323(5):C1524-C1538. doi: 10.1152/ajpcell.00195.2022. Epub 2022 Oct 3. PMID: 36189973; PMCID: PMC9829486

  • Senarathna J, Prasad A, Bhargava A, Gil S, Thakor NV, Pathak AP. HemoSYS: A Toolkit for Image-based Systems Biology of Tumor Hemodynamics. Sci Rep. 2020 Feb 11;10(1):2372. doi: 10.1038/s41598-020-58918-3. PMID: 32047171; PMCID: PMC7012876

  • Senarathna J, Yu H, Deng C, Zou AL, Issa JB, Hadjiabadi DH, Gil S, Wang Q, Tyler BM, Thakor NV, Pathak AP. A miniature multi-contrast microscope for functional imaging in freely behaving animals. Nat Commun. 2019 Jan 9;10(1):99. doi: 10.1038/s41467-018-07926-z. PMID: 30626878; PMCID: PMC6327063

Honors

  • Provost's Undergraduate Research Award, Johns Hopkins University
  • Junior Faculty Pilot Project Award, Johns Hopkins Institute for Nanobiotechnology, 1/1/10
  • Susan Komen Career Catalyst Award in Breast Cancer, 1/1/09
  • Elmer L. Lindseth Lectureship, Case Western Reserve University, 1/1/05
  • The Andrew Moissoff Young Investigator Award, Lymphatic Research Foundation, 1/1/04
  • Young Investigator Scholarship/Awarded by the Lymphatic Research Foundation, The Susan G. Komen Breast Cancer Foundation, 1/1/04
  • The Bill Negendank Young Investigator Award First Place for Outstanding Young Investigators in the Field of Cancer MR, Awarded by the International Society for Magnetic Resonance in Medicine, 1/1/02
  • Journal Publication Award, Medical College of Wisconsin Cancer Center Trainee Paper Competition, 1/1/01
  • Student Stipend Awards, International Society for Magnetic Resonance in Medicine, 1/1/98
  • Whitaker Foundation Functional Imaging Fellowship, Marquette University and Biophysics Research Institute, 1/1/97
  • Student Travel Award, Bioengineering Section of the American Society of Mechanical Engineering, 1/1/96
  • Research Assistantship, Marquette University, 1/1/94

Graduate Program Affiliations

  • Biomedical Engineering and Electrical Engineering

Memberships

  • World Molecular Imaging Society
  • International Society for Magnetic Resonance in Medicine (ISMRM)

Additional Training

Radiological Sciences, Johns Hopkins University, Baltimore, MD, 2003, Postdoctoral Fellowship

Expertise

Education

Medical College of Wisconsin - Milwaukee

Ph.D., 2001