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Ami Shah, MD
Rheumatology
- Johns Hopkins School of Medicine Faculty
4.8 of 5 stars
45 Ratings, 14 ReviewsLanguages
- Gujarati
- English
14 Insurances Accepted
View allGender
FemaleAbout Ami Shah
Professional Titles
- Director, Division of Rheumatology, Department of Medicine
- Co-Director, Johns Hopkins Scleroderma Center
- Deputy Director, Rheumatology Precision Medicine Centers of Excellence Clinical Programs
Primary Academic Title
Professor of Medicine
Background
Dr. Ami Shah is an Associate Professor of Medicine and Director of the Division of Rheumatology at the Johns Hopkins University School of Medicine. Dr. Shah also serves as the Co-Director of the Johns Hopkins Scleroderma Center. Her areas of clinical expertise include rheumatology, particularly scleroderma and Raynaud's phenomenon.
She is a graduate of the Massachusetts Institute of Technology and Johns Hopkins University School of Medicine. She completed her internal medicine residency training at Stanford University Hospital & Clinics and rheumatology post-doctoral fellowship at Johns Hopkins. During her fellowship training, she earned her Master of Health Science in Clinical Investigation at the Johns Hopkins Bloomberg School of Public Health.
Dr. Shah’s clinical practice is focused on the broad spectrum of patients with scleroderma and related disorders, and her expertise includes management of complications such as Raynaud’s phenomenon, digital ischemia, pulmonary hypertension, cardiac dysfunction, myopathy, aggressive skin disease and concomitant cancer. Dr. Shah teaches post-doctoral fellows in her clinic about the evaluation and management of scleroderma.
Dr. Shah’s research program has focused on the interface between cancer and autoimmunity in scleroderma, myositis and the newly emerging area of immune-related adverse events due to immune checkpoint inhibitor therapy. In highly collaborative studies, her group has published seminal observations linking cancer with the development of autoimmunity in scleroderma, with implications for cancer screening strategies in this population and the potential to shed insight into the pathogenesis of paraneoplastic rheumatic disease. In addition to her work in cancer and autoimmunity, Dr. Shah has an active research program in other clinical and therapeutic aspects of scleroderma, including early detection of cardiopulmonary complications and improving outcome measures and therapeutics for Raynaud's phenomenon. Dr. Shah also directs rheumatology precision medicine initiatives through the Johns Hopkins Individualized Health (inHealth) Initiative. The division’s program seeks to harness technological resources for comprehensive data collection and harmonization, strengthen novel data analytic approaches including defining unique patient subgroups, and accelerate the incorporation of discoveries into the delivery of clinical care.
Dr. Shah has been a recipient of the ACR Research and Education Foundation Clinical Investigator Fellowship Award. In 2018, her research contributions were recognized at the 5th Systemic Sclerosis World Congress with receipt of the Edith Busch Prize for Young Investigators. In 2020, she was honored to receive the prestigious Henry Kunkel Young Investigator Award from the American College of Rheumatology. She is a member of the American College of Rheumatology.
Centers and Institutes
Research Interests
Cancer Immune Related Adverse Events, Connection Between Cancer and Autoimmunity in the Rheumatic Diseases, Methods to Detect Cardiopulmonary Complications in Scleroderma, Scleroderma and Raynaud’s Phenomenon
Lab Website
Ami Shah Lab - Lab Website
- Researchers in the Ami Shah Lab study scleroderma and Raynaud's phenomenon. We examine the relationship between cancer and scleroderma, with a focus on how and if cancer causes scleroderma to develop in some patients. We are currently conducting clinical research to study ways to detect cardiopulmonary complications in patients with scleroderma, biological and imaging markers of Raynaud's phenomenon, and drugs that improve aspects of scleroderma.
Research Summary
Dr. Shah has an active research program studying various aspects of scleroderma and Raynaud’s phenomenon. She is investigating the connection between cancer and scleroderma, as her early data suggest cancer may drive the development of scleroderma in some patients. She also conducts epidemiological studies and participates in clinical trials to examine 1) methods to detect cardiopulmonary complications in scleroderma, 2) biological and imaging markers of Raynaud’s severity and 3) drugs that may improve various aspects of the disease (such as skin, lung or vascular complications).
Selected Publications
Shah AA, Casciola-Rosen L, Rosen A. Cancer-induced Autoimmunity in the Rheumatic Diseases. Arthritis Rheumatol. 2015 Feb;67(2):317-26. PMID: 25371098.
Shah AA, Laiho M, Rosen A, Casciola-Rosen L. Protective Effect Against Cancer of Antibodies to the Large Subunits of Both RNA polymerases-I and -III in Scleroderma. Arthritis Rheumatol. 2019;71(9):1571-9. PMID: 30888702
Shah AA, Rosen A, Hummers L, Wigley F, Casciola-Rosen L. Close Temporal Relationship Between Onset of Cancer and Scleroderma in Patients with RNA Polymerase I/III Antibodies. Arthritis Rheum. 2010 Sep; 62(9): 2787-95. PMID: 20506513
Igusa T, Hummers LK, Visvanathan K, Richardson C, Wigley FM, Casciola-Rosen L, Rosen A, Shah AA. Autoantibodies and scleroderma phenotype define subgroups at high-risk and low-risk for cancer. Ann Rheum Dis. 2018;77(8):1179-1186. doi: 10.1136/annrheumdis-2018-212999. PMID: 296788941
Joseph CG, Darrah E, Shah AA, Skora AD, Casciola-Rosen LA, Wigley FM, Boin F, Fava A, Thoburn C, Kinde I, Jiao Y, Papadopoulos N, Kinzler KW, Vogelstein B, Rosen A. Association of the autoimmune disease scleroderma with an immunologic response to cancer. Science. 2014 Jan 10;343(6167):152-7. PMID: 24310608.
Honors
- Edith Busch Prize for Young Investigators, Edith Busch Foundation and 5th Systemic Sclerosis World Congress
- Henry Kunkel Young Investigator Award, American College of Rheumatology
- Career Development Bridge Funding Award, American College of Rheumatology Research and Education Foundation and Arthritis Foundation, 1/1/11
- Delta Omega Alpha, Johns Hopkins Bloomberg School of Public Health, 1/1/10
- Clinical Investigator Fellowship Award, American College of Rheumatology Research and Education Foundation, 1/1/09
- Alpha Omega Alpha, Johns Hopkins University School of Medicine, 1/1/03
- Phi Beta Kappa, Massachusetts Institute of Technology, 1/1/99
- Burchard's Scholar, Massachusetts Institute of Technology, 1/1/98
Memberships
- American College of Rheumatology
Locations
- Johns Hopkins Bayview Medical Center
- 5501 Hopkins Bayview Circle, Floor 1, Baltimore, MD 21224
- phone: 443-997-1552
- fax: 410-550-1033
Expertise
Education
Johns Hopkins Bloomberg School of Public Health
Graduate SchoolJohns Hopkins University School of Medicine
Fellowship, Rheumatology, 2009Stanford University School of Medicine
Residency, Internal Medicine, 2006Johns Hopkins University School of Medicine
Medical Education, MD, 2003Board Certifications
Rheumatology
American Board of Internal Medicine, 2009Internal Medicine
American Board of Internal Medicine, 2006Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Humana
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- UnitedHealthcare
- Veteran Affairs Community Care Network (Optum-VACCN)
Ratings & Reviews
4.8 out of 5
45 ratings, 14 reviewsThe Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
- 5 out of 5 starsReviewed on 1/7/2025
Dr. Shah is thorough, informative, and concerned. She makes appropriate suggestions and when I leave I feel like I have control over my illness.
- 5 out of 5 starsReviewed on 12/10/2024
The most expert in my condition. She is always concerned
- 5 out of 5 starsReviewed on 12/3/2024
Dr Shah has been excellent in helping me to continue improving.
- 5 out of 5 starsReviewed on 11/26/2024
She is always positive toward me, my current treatment, my future, all the aspects of my life ending disease. She always makes me feel better about myself and hopeful about tomorrow.
- 5 out of 5 starsReviewed on 11/26/2024
Dr. Shah is an outstanding doctor. She is always thorough, compassionate and knowledgeable.
- 5 out of 5 starsReviewed on 10/15/2024
Dr. Shah is fantastic! I continue to feel very grateful that she is my doctor. She is so knowledgeable about the disease and has always worked with me to achieve the best results possible. I feel very well cared for.
- 5 out of 5 starsReviewed on 10/8/2024
Extremely caring, professional, completely in touch with my disease, symptoms, and conerns.
- 5 out of 5 starsReviewed on 10/8/2024
She is kind, courteous and very thorough. I feel she is an excellent physician
- 5 out of 5 starsReviewed on 9/24/2024
Dr. Shah is a real gem. She is very thorough, dedicated, sensitive to patient needs, and listens carefully.
- 5 out of 5 starsReviewed on 6/18/2024
Dr. Shah is outstanding in every respect.
- 5 out of 5 starsReviewed on 6/4/2024
Very professional, very caring, very knowledgeable
- 5 out of 5 starsReviewed on 5/21/2024
I have been Dr. Shah's patient for many years traveling back and forth from Florida for my appointments before retiring in Delaware. Her knowledge and compassionate care exceeded my expectations. She stays in communication with my other Hopkins providers and works as a team with them to provide the best care to me. She is an excellent example of the exceptional care that Johns Hopkins is known for.
- 5 out of 5 starsReviewed on 3/19/2024
Dr shah is very thorough and professional. She goes over all my concerns and discusses solutions to my problems.
- 5 out of 5 starsReviewed on 2/27/2024
Dr Shah provided an excellent service.