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Ami Shah

Ami Shah, MD

Rheumatology

Accepting New Patients
Johns Hopkins Affiliations:
  • Johns Hopkins School of Medicine Faculty

Languages

  • Gujarati
  • English

14 Insurances Accepted

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Gender

Female

About Ami Shah

Professional Titles

  • Director, Division of Rheumatology, Department of Medicine
  • Co-Director, Johns Hopkins Scleroderma Center
  • Deputy Director, Rheumatology Precision Medicine Centers of Excellence Clinical Programs

Primary Academic Title

Professor of Medicine

Background

Dr. Ami Shah is an Associate Professor of Medicine and Director of the Division of Rheumatology at the Johns Hopkins University School of Medicine. Dr. Shah also serves as the Co-Director of the Johns Hopkins Scleroderma Center. Her areas of clinical expertise include rheumatology, particularly scleroderma and Raynaud's phenomenon. 

She is a graduate of the Massachusetts Institute of Technology and Johns Hopkins University School of Medicine. She completed her internal medicine residency training at Stanford University Hospital & Clinics and rheumatology post-doctoral fellowship at Johns Hopkins.  During her fellowship training, she earned her Master of Health Science in Clinical Investigation at the Johns Hopkins Bloomberg School of Public Health.

Dr. Shah’s clinical practice is focused on the broad spectrum of patients with scleroderma and related disorders, and her expertise includes management of complications such as Raynaud’s phenomenon, digital ischemia, pulmonary hypertension, cardiac dysfunction, myopathy, aggressive skin disease and concomitant cancer. Dr. Shah teaches post-doctoral fellows in her clinic about the evaluation and management of scleroderma. 

Dr. Shah’s research program has focused on the interface between cancer and autoimmunity in scleroderma, myositis and the newly emerging area of immune-related adverse events due to immune checkpoint inhibitor therapy. In highly collaborative studies, her group has published seminal observations linking cancer with the development of autoimmunity in scleroderma, with implications for cancer screening strategies in this population and the potential to shed insight into the pathogenesis of paraneoplastic rheumatic disease. In addition to her work in cancer and autoimmunity, Dr. Shah has an active research program in other clinical and therapeutic aspects of scleroderma, including early detection of cardiopulmonary complications and improving outcome measures and therapeutics for Raynaud's phenomenon. Dr. Shah also directs rheumatology precision medicine initiatives through the Johns Hopkins Individualized Health (inHealth) Initiative. The division’s program seeks to harness technological resources for comprehensive data collection and harmonization, strengthen novel data analytic approaches including defining unique patient subgroups, and accelerate the incorporation of discoveries into the delivery of clinical care.

Dr. Shah has been a recipient of the ACR Research and Education Foundation Clinical Investigator Fellowship Award. In 2018, her research contributions were recognized at the 5th Systemic Sclerosis World Congress with receipt of the Edith Busch Prize for Young Investigators. In 2020, she was honored to receive the prestigious Henry Kunkel Young Investigator Award from the American College of Rheumatology. She is a member of the American College of Rheumatology.

Centers and Institutes

Scleroderma Center

Research Interests

Cancer Immune Related Adverse Events, Connection Between Cancer and Autoimmunity in the Rheumatic Diseases, Methods to Detect Cardiopulmonary Complications in Scleroderma, Scleroderma and Raynaud’s Phenomenon

Lab Website

Ami Shah Lab - Lab Website

  • Researchers in the Ami Shah Lab study scleroderma and Raynaud's phenomenon. We examine the relationship between cancer and scleroderma, with a focus on how and if cancer causes scleroderma to develop in some patients. We are currently conducting clinical research to study ways to detect cardiopulmonary complications in patients with scleroderma, biological and imaging markers of Raynaud's phenomenon, and drugs that improve aspects of scleroderma.

Research Summary

Dr. Shah has an active research program studying various aspects of scleroderma and Raynaud’s phenomenon. She is investigating the connection between cancer and scleroderma, as her early data suggest cancer may drive the development of scleroderma in some patients. She also conducts epidemiological studies and participates in clinical trials to examine 1) methods to detect cardiopulmonary complications in scleroderma, 2) biological and imaging markers of Raynaud’s severity and 3) drugs that may improve various aspects of the disease (such as skin, lung or vascular complications).

Selected Publications

  • Shah AA, Casciola-Rosen L, Rosen A. Cancer-induced Autoimmunity in the Rheumatic Diseases. Arthritis Rheumatol. 2015 Feb;67(2):317-26. PMID: 25371098.

  • Shah AA, Laiho M, Rosen A, Casciola-Rosen L. Protective Effect Against Cancer of Antibodies to the Large Subunits of Both RNA polymerases-I and -III in Scleroderma. Arthritis Rheumatol. 2019;71(9):1571-9. PMID: 30888702

  • Shah AA, Rosen A, Hummers L, Wigley F, Casciola-Rosen L. Close Temporal Relationship Between Onset of Cancer and Scleroderma in Patients with RNA Polymerase I/III Antibodies. Arthritis Rheum. 2010 Sep; 62(9): 2787-95. PMID: 20506513

  • Igusa T, Hummers LK, Visvanathan K, Richardson C, Wigley FM, Casciola-Rosen L, Rosen A, Shah AA. Autoantibodies and scleroderma phenotype define subgroups at high-risk and low-risk for cancer. Ann Rheum Dis. 2018;77(8):1179-1186. doi: 10.1136/annrheumdis-2018-212999. PMID: 296788941

  • Joseph CG, Darrah E, Shah AA, Skora AD, Casciola-Rosen LA, Wigley FM, Boin F, Fava A, Thoburn C, Kinde I, Jiao Y, Papadopoulos N, Kinzler KW, Vogelstein B, Rosen A. Association of the autoimmune disease scleroderma with an immunologic response to cancer. Science. 2014 Jan 10;343(6167):152-7. PMID: 24310608.

Honors

  • Edith Busch Prize for Young Investigators, Edith Busch Foundation and 5th Systemic Sclerosis World Congress
  • Henry Kunkel Young Investigator Award, American College of Rheumatology
  • Career Development Bridge Funding Award, American College of Rheumatology Research and Education Foundation and Arthritis Foundation, 1/1/11
  • Delta Omega Alpha, Johns Hopkins Bloomberg School of Public Health, 1/1/10
  • Clinical Investigator Fellowship Award, American College of Rheumatology Research and Education Foundation, 1/1/09
  • Alpha Omega Alpha, Johns Hopkins University School of Medicine, 1/1/03
  • Phi Beta Kappa, Massachusetts Institute of Technology, 1/1/99
  • Burchard's Scholar, Massachusetts Institute of Technology, 1/1/98

Memberships

  • American College of Rheumatology

Locations

  1. Johns Hopkins Bayview Medical Center
    • 5501 Hopkins Bayview Circle, Floor 1, Baltimore, MD 21224

    Expertise

    Education

    Johns Hopkins Bloomberg School of Public Health

    Graduate School

    Johns Hopkins University School of Medicine

    Fellowship, Rheumatology, 2009

    Stanford University School of Medicine

    Residency, Internal Medicine, 2006

    Johns Hopkins University School of Medicine

    Medical Education, MD, 2003

    Board Certifications

    Rheumatology

    American Board of Internal Medicine, 2009

    Internal Medicine

    American Board of Internal Medicine, 2006

    Insurance

    Johns Hopkins providers accept various commercial health insurance plans. However, they may not be included in all of an insurance company's plans or offerings. This may include Exchange, Medicaid, Medicare, and specific limited benefit plans. Exceptions to participation also exist based on your employer’s benefits package and the provider's location or specialty. Please contact your insurer directly to make sure your doctor is covered by your plan. For more details, please review our Insurance Information.
    Search plans
    • Aetna
    • CareFirst
    • Cigna
    • First Health
    • Geisinger Health Plan
    • HealthSmart/Accel
    • Humana
    • Johns Hopkins Health Plans
    • MultiPlan
    • Pennsylvania's Preferred Health Networks (PPHN)
    • Point Comfort Underwriters
    • Private Healthcare Systems (PHCS)
    • UnitedHealthcare
    • Veteran Affairs Community Care Network (Optum-VACCN)

    Ratings & Reviews

    4.8 out of 5

    45 ratings, 14 reviews

    The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

    Overall Rating by Patient
    Average provider Overall Rating by Patient rating 4.8 out of 5 stars
    Provider Listened Carefully
    Average provider Provider Listened Carefully rating 4.9 out of 5 stars
    Provider Explained Things Clearly
    Average provider Provider Explained Things Clearly rating 4.9 out of 5 stars
    Provider Knew Medical History
    Average provider Provider Knew Medical History rating 4.9 out of 5 stars
    Provider Showed Respect
    Average provider Provider Showed Respect rating 4.9 out of 5 stars
    Provider Spent Enough Time
    Average provider Provider Spent Enough Time rating 4.7 out of 5 stars
    Search reviews
      5 out of 5 stars
      Reviewed on 1/7/2025

      Dr. Shah is thorough, informative, and concerned. She makes appropriate suggestions and when I leave I feel like I have control over my illness.

      5 out of 5 stars
      Reviewed on 12/10/2024

      The most expert in my condition. She is always concerned

      5 out of 5 stars
      Reviewed on 12/3/2024

      Dr Shah has been excellent in helping me to continue improving.

      5 out of 5 stars
      Reviewed on 11/26/2024

      She is always positive toward me, my current treatment, my future, all the aspects of my life ending disease. She always makes me feel better about myself and hopeful about tomorrow.

      5 out of 5 stars
      Reviewed on 11/26/2024

      Dr. Shah is an outstanding doctor. She is always thorough, compassionate and knowledgeable.

      5 out of 5 stars
      Reviewed on 10/15/2024

      Dr. Shah is fantastic! I continue to feel very grateful that she is my doctor. She is so knowledgeable about the disease and has always worked with me to achieve the best results possible. I feel very well cared for.

      5 out of 5 stars
      Reviewed on 10/8/2024

      Extremely caring, professional, completely in touch with my disease, symptoms, and conerns.

      5 out of 5 stars
      Reviewed on 10/8/2024

      She is kind, courteous and very thorough. I feel she is an excellent physician

      5 out of 5 stars
      Reviewed on 9/24/2024

      Dr. Shah is a real gem. She is very thorough, dedicated, sensitive to patient needs, and listens carefully.

      5 out of 5 stars
      Reviewed on 6/18/2024

      Dr. Shah is outstanding in every respect.

      5 out of 5 stars
      Reviewed on 6/4/2024

      Very professional, very caring, very knowledgeable

      5 out of 5 stars
      Reviewed on 5/21/2024

      I have been Dr. Shah's patient for many years traveling back and forth from Florida for my appointments before retiring in Delaware. Her knowledge and compassionate care exceeded my expectations. She stays in communication with my other Hopkins providers and works as a team with them to provide the best care to me. She is an excellent example of the exceptional care that Johns Hopkins is known for.

      5 out of 5 stars
      Reviewed on 3/19/2024

      Dr shah is very thorough and professional. She goes over all my concerns and discusses solutions to my problems.

      5 out of 5 stars
      Reviewed on 2/27/2024

      Dr Shah provided an excellent service.