
Ahizechukwu Eke, MBCHB, MPH, PhD
Maternal and Fetal Medicine
Obstetrics
- Johns Hopkins School of Medicine Faculty
About Ahizechukwu Eke
Professional Titles
- Director of Research, Division of Maternal Fetal Medicine
Primary Academic Title
Associate Professor of Gynecology and Obstetrics
Background
Ahizechukwu C Eke, M.B. ChB., Ph.D., M.P.H., is a specialist in maternal-fetal medicine with areas of clinical and research expertise in medical and surgical complications of pregnancy with a focus on prediction and prevention of preterm birth, pharmacokinetics, pharmacodynamics, pharmacoepidemiology, pharmacogenomics, pharmacomicrobiomics, maternal-fetal medicine, multiple pregnancies, obstetric ultrasound and HIV in pregnancy.
Dr. Eke earned his undergraduate degree from Federal Government College, Wukari, Taraba State, Nigeria, and his medical degree from the College of Medicine, University of Calabar, Nigeria. He completed two obstetrics and gynecology residencies – at the Nnamdi Azikiwe University Teaching Hospital, Nigeria (2005-2010) and at Michigan State University/Sparrow Hospital, which he completed in 2016, and then completed Maternal-Fetal Medicine and Clinical Pharmacology fellowships at the Johns Hopkins University School of Medicine in Baltimore, Maryland in 2019. He earned an MPH from the Harvard University School of Public Health in 2011, and a PhD in Clinical Investigation from the Johns Hopkins University School of Public Health Graduate Training Program in Clinical Investigation (GTPCI) in 2021. He joined the Johns Hopkins faculty in 2019.
Dr. Eke serves on a number of national and international boards and committees. He is a member of Alpha Omega Alpha (AOA), Delta Omega Alpha (DOA), the American College of Obstetrics and Gynecology (ACOG), the American Medical Association (AMA), the American Society for Clinical Investigation (ASCI), the Society of Maternal-Fetal Medicine (SMFM), the American Public Health Association (APHA), the West African College of Surgeons (FWACS), and the Infectious Disease Society of Obstetrics and Gynecology. He currently serves on the Committee on Practice Bulletins (CPG) of ACOG, and is a member of the National Academies of Sciences, Engineering and Medicine (NASEM) committee on 'Developing a framework to address legal, ethical, regulatory, and policy issues for research specific to pregnant and lactating Persons'. Dr. Eke is an editorial board member of Obstetrics and Gynecology (the Green Journal) and the New England Journal of Medicine (NEJM Evidence). He is an active member of NIH study sections.
Dr. Eke has published several articles in obstetrics and maternal-fetal medicine journals, and written numerous textbook chapters. He is a journal reviewer for several peer-reviewed journals in his specialty, including Obstetrics & Gynecology (Green Journal), American Journal of Obstetrics and Gynecology (Gray Journal), and the International Journal of Obstetrics and Gynecology.
Centers and Institutes
Clinical Trial Keywords
Pharmacoepidemiology, Pharmacokinetics, Pharmacodynamics, Pharmacogenomics, Pharmacomicrobiomics, Preterm birth
Recent News Articles and Media Coverage
Winning the 2017 Kenneth Warren Prize, Cochrane Collaboration (February 22, 2018)
Pharmacologic research in pregnant women – Time to get it right, Global News (April 21, 2019)
Examining adverse pregnancy outcomes in people living with HIV, Managed Healthcare Executive (Mar 21, 2023)
New study affirms link between sickle cell disease and risk of increased mortality in pregnant people, NewsWise (Feb 2, 2023)
Contact for Research Inquiries
600 N Wolfe Street
Phipps 228
Baltimore, MD 21287
Research Interests
HIV in pregnancy, Maternal Health Policy, Medical and Surgical Complications in Pregnancy, Pharmacodynamics, Pharmacoepidemiology, Pharmacogenomics, Pharmacokinetics, Pharmacomicrobiomics, Preterm birth
Lab Website
Maternal-Fetal Medicine Research - Lab Website
- The Division of Maternal-Fetal Medicine is engaged in clinical, basic bench and epidemiological research as one of its primary missions. Our strength lies in the expertise and diverse interests of our faculty, as well as in the collaborations with multiple other disciplines and departments throughout the School of Medicine, The Bloomberg School of Public Health, and the School of Biomedical Engineering. The strong research infrastructure of the Johns Hopkins University forms a solid foundation for the success of our integrated research program for Maternal-Fetal Medicine.
Research Summary
Preterm birth, Pharmacokinetics, Pharmacodynamics, Pharmacoepidemiology, Pharmacogenomics, Pharmacomicrobiomics, HIV in pregnancy, Maternal Health Policy, medical and surgical complications in pregnancy.
Research Gate
Selected Publications
Eke AC, Chakhtoura N, Kashuba A, Best BM, Sykes C, Wang J, Stek AM, Smith E, Calabrese S, Capparelli EV, Mirochnick M; IMPAACT P1026s Protocol Team. Rilpivirine Plasma and Cervicovaginal Concentrations in Women During Pregnancy and Postpartum. J Acquir Immune Defic Syndr. 2018; 78(3):308-313.
Eke AC, Dooley KE, Sheffield JS. Pharmacologic Research in Pregnant Women - Time to Get It Right. N Engl J Med. 2019; 380(14):1293-1295.
Eke AC, McCormack SA, Best BM, Stek AM, Wang J, Kreitchmann R, Shapiro D, Smith E, Mofenson LM, Capparelli EV, Mirochnick M; IMPAACT P1026s Protocol Team. Pharmacokinetics of Increased Nelfinavir Plasma Concentrations in Women During Pregnancy and Postpartum. J Clin Pharmacol. 2019; 59(3):386-393.
Eke AC, Mirochnick M, Lockman S. Antiretroviral Therapy and Adverse Pregnancy Outcomes in People Living with HIV. N Engl J Med. 2023; 388(4):344-356.
Bienstock JL, Eke AC, Hueppchen NA. Postpartum Hemorrhage. N Eng J Med. 2021; 384(17):1635-1645.
Honors
- Inductee, Delta Omega Alpha (DOA) Honor Public Health Society
- ASCI Young Physician Scientist Award, The American Society for Clinical Investigation (ASCI), 4/20/23
- AGOS Presidential Travel Award, The American Gynecological Obstetrical Society (AGOS), 6/18/22
- Distinguished Teaching Society (DTS) of the JHU SOM, Johns Hopkins University School of Medicine, 4/18/21
- American College of Obstetrics & Gynecology (ACOG) Warren Pearse Health Policy Award, American College of Obstetrics & Gynecology, 5/4/19
- Society for Reproductive Investigation (SRI) Pfizer Presidential Award, Society for Reproductive Investigation, 3/15/19
- Cochrane Kenneth Warren Prize for best high quality methodological review, Cochrane Collaboration, Cochrane Collaboration, 9/15/17
- Paul Leitman's Global Health Fellowship Travel Award, Johns Hopkins University School of Medicine, Johns Hopkins University School of Medicine, 4/18/17
- Society for Reproductive Investigation (SRI) award for Best New Investigator poster presentation, Society for Reproductive Investigation, 3/16/17
- Michigan State University Outstanding Award for Best Medical Student/Resident Educator, Michigan State University, 6/17/16
- American Congress of Obstetricians and Gynecologists (ACOG) Donald Richardson's Paper Prize National Award, American Congress of Obstetricians and Gynecologists, 5/15/16
- Ephraim McDowell Award for best Junior Fellow research paper in ACOG District V, American College of Obstetrics & Gynecology, 9/19/15
- National Institute of Health (NIH)/National Medical Association Scholar, National Medical Association, 8/2/15
- Society for Maternal Fetal Medicine (SMFM) Resident Award for Excellence in Obstetrics, Society for Maternal Fetal Medicine, 5/7/15
- Michigan State University Outstanding Award for Best Medical Student/Resident Educator, Michigan State University, 3/20/15
- American Congress of Obstetricians and Gynecologists (ACOG) Junior Fellow Rising Star in Advocacy National Award, American Congress of Obstetricians and Gynecologists, 3/9/15
- Society for Maternal Fetal Medicine (SMFM) Quilligan Scholar, Society for Maternal Fetal Medicine, 2/5/15
- American Medical Association (AMA) Foundation National Excellence in Medicine Leadership Award for outstanding leadership skills, American Medical Association, 6/9/14
- Inductee, Alpha Omega Alpha (AOA) Honor Medical Society, Michigan State University, Alpha Omega Alpha (AOA) Honor Medical Society, 5/21/14
- Winning oral presentation, ACOG Junior fellow District V Resident research day, Louisville Kentucky, American College of Obstetricians & Gynecologists, 10/11/13
- HIVMA travel Scholarship, 2012 to the World's AIDS Conference, Washington DC., HIVMA, 7/23/12
- Diversity Minority Fellowship Award, Barnes Jewish Hospital, St Louis, Barnes Jewish Hospital, St Louis, 7/11/12
- Fellow, West African College of Surgeons (FWACS), 4/3/12
- Nominated for the Albert Schweitzer Award, the highest accolade for students graduating from the HSPH, Harvard School of Public Health, 5/16/11
- A.G. Leventis Scholarship Award for Academic Excellence, Harvard School of Public Health, Harvard School of Public Health, 4/13/11
- Essay winner, Global Forum for Health Research/Lancet International Essay Competition, 2007, Global Forum for Health Research, 5/10/07
Graduate Program Affiliations
Director, Maternal-Fetal Medicine Research
Memberships
- Society for Maternal Fetal Medicine
- American College of Obstetricians and Gynecologists (ACOG)
- West African College of Surgeons (WACS)
- National Postgraduate Medical College of Nigeria
- Royal College of Obstetricians & Gynecologists
- Cochrane Collaboration
- American Public Health Association
- American Medical Association
- Nigerian Medical Association
- International College of Surgeons (ICS)
- International Leadership Association (ILA)
Professional Activities
- American Board of Clinical Pharmacology, Diplomate, 5/9/20
- American College of Obstetricians & Gynecologists (ACOG), Fellow, 11/9/17
- West African College of Surgeons, Fellow, 4/3/12
Additional Training
- MPH: Harvard T H Chan School of Public Health (2011)
- PhD: Johns Hopkins Bloomberg School of Public Health (2021)
Locations
- Gynecology and Obstetrics - Nelson/Harvey Building
- 1800 Orleans Street, Nelson BLDG, 2 Floor Ste 2-150, Baltimore, MD 21287
- phone: 410-502-3200
- fax: 410-367-2911
- Johns Hopkins Community Physicians - Johns Hopkins Health Care & Surgery Center, White Marsh
- 4924 Campbell Boulevard, Suite 225, Nottingham, MD 21236
- phone: 443-997-0400
- fax: 410-367-3320
Expertise
Education
Johns Hopkins Bloomberg School of Public Health
Graduate School, Clinical Investigation, PhD, 2021Johns Hopkins University School of Medicine
Fellowship, Maternal & Fetal Medicine, 2019University of Michigan Health Sparrow
Residency, Obstetrics and Gynecology, 2016Harvard T H Chan School of Public Health
Graduate School, Public Health, MPH, 2011Nnamdi Azikiwe University Teaching Hospital
Residency, Obstetrics and Gynecology, 2010University of Calabar College of Medical Sciences
Medical Education, MBChB, 2003Board Certifications
Maternal and Fetal Medicine
American Board of Obstetrics and Gynecology, 2021Clinical Pharmacology
American Board of Clinical Pharmacology, 2020Obstetrics and Gynecology
American Board of Obstetrics and Gynecology, 2017Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Humana
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- UnitedHealthcare
- Veteran Affairs Community Care Network (Optum-VACCN)