We were close to finalizing the feature stories in this issue of Hopkins Medicine magazine when our world — seemingly overnight — was turned upside down by COVID-19, the global pandemic that has shut down countries; caused untold anxiety, suffering and death; and put health care workers on the front lines of a grueling, life-and-death battle that could stretch on for months. In the special section that follows, a late-breaking supplement to the other content in this issue that had been completed pre-pandemic, you’ll read about just some of the ways that people at Johns Hopkins Medicine are rising to the unprecedented challenges posed by COVID-19: in the lab, at the bedside and in the community.