Brain Health Program

The Johns Hopkins / University of Texas Southwestern Brain Health Program is a multi-specialty team of experts from the Johns Hopkins School of Medicine, Whiting School of Engineering, the Bloomberg School of Public Health and the University of Texas Southwestern Medical Center. In the hope of revealing new directions for therapies, we study molecular biomarkers identified from tissue and brain imaging that are associated with memory problems related to HIV infection, aging, dementia, mental illness and traumatic brain injury.

We are implementing novel clinical assessments and developing new mathematical models to put our findings into action. The team seeks to advance policies and practices to optimize brain health in vulnerable populations while destigmatizing these brain disorders.

Our Team

Our team is led by Leah H. Rubin, Ph.D., MPH and Jennifer Coughlin, M.D., and includes investigators, graduate and undergraduate clinical research coordinators, volunteers and other collaborators passionate about our mission.

Our Clinical Research Studies

Our team is conducting several clinical studies that are recruiting participant. If you are interested in participating in a study, please call 443-287-4701 or email [email protected].

You may be eligible to participate in a study if you answer yes to any of the items below. When you email or call about participating, please include what applies to you from these lists.

Do you fall into any of the following groups?

  • A person living with a mental health condition
    • Mood disorder (depression, bipolar)
    • Anxiety disorder
    • Post-traumatic stress disorder (PTSD)
    • Psychosis (schizophrenia)
  • A person living with significant memory problems
    • Mild cognitive impairment
    • Alzheimer’s disease
  • A person with a history of substance misuse who has abstained for at least three months
  • A person living with long COVID
  • A person living with HIV

Are you interested in participating in a research study that focuses on brain health?

  • Are you willing to complete paper and pencil and computerized assessments of memory and other mental abilities and mood assessments?
  • Are you willing to have your blood drawn?
  • Are you willing to undergo an MRI (brain scan)?
  • Are you willing to undergo a PET scan (requires an arterial line; an option for participants at UT Southwestern)?
  • Are you willing to have a lumbar puncture (optional)?

Support the Brain Health Program

We are grateful for your support of the Brain Health Program. Your gift creates impact and helps fuel our important work to improve cognitive and mental health for all individuals in vulnerable populations.