Vision
Understand the factors that underlie the pathobiology of COVID-19, the progression to severe illness or death, and the effectiveness of therapeutic interventions in order to provide personalized care to patients infected with SARS-CoV-2.
Mission
Improve the care of patients infected with SARS-CoV-2 by learning about COVID-19 pathobiology, likelihood of disease progression and impact of specific therapeutic interventions. We aim to provide this information to clinicians, patients and family members at the point of care.
COVID-19 Research and Precision Medicine
The research aims that inform us on how to best care for patients include:
COVID-19 Disease Trajectory
Characterize the longitudinal trajectories of patients infected with SARS-CoV-2 to inform research questions and clinical care.
![hexagon pattern](/-/media/inhealth/images/icons/big-data-icon.jpg?h=440&iar=0&w=640&hash=6BFFC6DFB02622E4B34C835C0FD1E3D8)
Prediction Modeling
Develop prediction models of COVID-19 severe disease and death that can be used at the point of care to inform treatment decisions, resource allocation and discussions with patients and families.
![microscope](/-/media/inhealth/images/icons/innovation.jpg?h=440&iar=0&w=640&hash=600526BAA95460B268E98E486862349D)
Effectiveness of Therapeutic Interventions
Examine the impact of different treatment interventions on COVID-19 outcomes.
![clipboard](/-/media/inhealth/images/icons/clipboard.jpg?h=440&iar=0&w=640&hash=85E6C6583DA046C3C242AD1E1331B1D6)
Racial and Social Inequities
Explore racial and social inequities in COVID-19 diagnosis and management.
![doctor with stethoscope](/-/media/inhealth/images/icons/icon-doctor-stethoscope-patient.jpg?h=440&iar=0&w=640&hash=0CE903DB696A658BF44E64AEA43B2E1D)
Developed by Our Team
COVID-19 Precision Medicine Analytics Platform Registry (JH-CROWN)
Johns Hopkins has created the JH-CROWN registry to gather information on all of the patients who have been seen at our health system with suspected or confirmed COVID-19. It will be used to learn about the pathobiology of COVID-19 and to better understand patient outcomes.
COVID Inpatient Risk Calculator (CIRC)
The COVID Inpatient Risk Calculator (CIRC) uses factors on admission to the hospital to predict the likelihood that a patient admitted with COVID-19 will progress to severe disease or death within 7 days of arrival. We are excited that it is now also available on MDCalc.
Severe COVID-19 Adaptive Risk Predictor (SCARP)
The COVID-19 adaptive risk predictor (SCARP) is a tool that calculates the 1-day and 7-day risk of progression to severe disease or death for adult patients (18 years and older) who are hospitalized with COVID-19.
Selected Sample of Peer-Reviewed Manuscripts
- Racial and Ethnic Discrepancy in Pulse Oximetry and Delayed Identification of Treatment Eligibility Among Patients With COVID-19
- Patient Trajectories Among Persons Hospitalized for COVID-19 : A Cohort Study
- Development of Severe COVID-19 Adaptive Risk Predictor (SCARP), a Calculator to Predict Severe Disease or Death in Hospitalized Patients With COVID-19
- Clinical Outcomes Associated With Overestimation of Oxygen Saturation by Pulse Oximetry in Patients Hospitalized With COVID-19
- Real-World Effectiveness Of Remdesivir In Adults Hospitalized With Covid-19
- Sex and gender differences in testing, hospital admission, clinical presentation, and drivers of severe outcomes from COVID-19
- The Effectiveness of High-Flow Nasal Cannula in Coronavirus Disease 2019 Pneumonia: A Retrospective Cohort Study
- IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function
Coronavirus Research
Johns Hopkins Medicine researchers are working tirelessly to find ways to better understand, treat and eventually eliminate COVID-19 and the illness that results from infection. In addition, Johns Hopkins researchers are conducting a variety of clinical trials to find new ways to detect, prevent and treat COVID-19.
Patient Care for COVID-19
The Johns Hopkins biocontainment unit is a state-of-the art-facility designed to care for patients affected by high-consequence infectious diseases such as COVID-19. The unit is a multidisciplinary collaboration of experts from across the Johns Hopkins Health System and around the world. Find out more about the biocontainment unit.