It is estimated that nearly 10,000 men will develop testis cancer each year in the United States. The chance of developing testis cancer is about one in 270. Fortunately, the cure rate is excellent (greater than 95 percent for all men with testis cancer). Only about 400 men will die from testis cancer each year (the chance of death from testis cancer is better than one in 5,000). Because of the excellent cure rate, about 20,000 are surviving with cancer and 200,000 have been cured at any given time in the United States.

Testis cancer is most common in men in their late 20s and early 30s, with an average age of diagnosis of 33 years old. In fact, testis cancer is the most common malignancy among men 20 to 40 years old. However, testis cancer can occur at any age: It is the second most common malignancy in young men 15 to 19 years old (leukemia is the most common.), with approximately 6 percent of cases occurring in children and teens, and about 7 percent occurring in men over the age of 55.

In the United States, testis cancer is most common in white (Caucasian) men compared to other races, but is not exclusive to Caucasians. The incidence of testicular cancer among Hispanic or Latino men is on the rise and may present at a younger age, yet more advanced stage, underscoring the importance of awareness, access to care, early diagnosis and prompt treatment. Worldwide, the risk of developing testis cancer is highest in the United States and Europe and lowest among men living in Africa or Asia.