Activation (Stage 3) Clinical Research Lifecycle
From receipt of protocol approval(s) through initiation of participant screening
![Research Lifecycle diagram with Activation (step three) highlighted](/-/media/migration/all-childrens-hospital/images/academics/research/clinical-research-lifecycle/03-activation/03-activation.png)
During this busy stage the research team and participating departments ensure all internal processes are in place in order to be able to execute the protocol. Including, but limited to:
- Finalizing data collection instruments
- Finalizing funding sources
- Executing contract
- Training team(s) on the protocol
- Communicating with and among centralized support groups / shared services.
CTRO research professionals can assist the PI in fulfilling his/her responsibility to ensure that all pre-activation activities are complete prior to screening and enrolling participants
During this stage the following centralized support groups / shared services may be engaged:
- Research Operations
- Clinical Research Unit (CRU)
- Investigational Drug Services (IDS)
- Biorepository
- Research & Grants Administration
- Post Award Activities
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- Training and Re-Consent Assessment
- Protocol Training Documentation
- Protocol Training / Transition Form Part A
- Protocol Training / Transition form Part B
- Protocol Training Agenda
- Training Attendance Sign-in Sheet
- Self-Study Training Documentation
- DOA Log
- DOA Log Sub-Site
- Delegation of Research Tasks Key
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Phase 2: Submission & Review
From submission through approval by all applicable internal and external committees.
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Phase 4: Conduct
From screening of first participant through completion of last participant last visit (LPLV)